Identification |
HMDB Protein ID
| CDBP03705 |
Secondary Accession Numbers
| Not Available |
Name
| NTF2-related export protein 1 |
Description
| Not Available |
Synonyms
|
- Protein p15
|
Gene Name
| NXT1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in transport |
Specific Function
| Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5 |
GO Classification
|
Component |
cell part |
intracellular |
Process |
establishment of localization |
transport |
|
Cellular Location
|
- Nucleus
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 20p12-p11.2 |
SNPs
| NXT1 |
Gene Sequence
|
>423 bp
ATGGCATCTGTGGATTTCAAGACCTATGTGGATCAGGCCTGCAGAGCTGCTGAGGAGTTT
GTCAATGTCTACTACACCACCATGGATAAGCGGCGGCGTTTGCTGTCCCGCCTGTACATG
GGCACAGCCACCCTGGTCTGGAATGGCAATGCTGTTTCAGGACAAGAATCCTTGAGTGAG
TTTTTTGAAATGTTGCCTTCCAGCGAGTTCCAAATCAGCGTGGTAGACTGCCAGCCTGTT
CATGATGAAGCCACACCAAGCCAGACCACGGTCCTTGTTGTCATCTGTGGATCAGTGAAG
TTTGAGGGGAACAAACAACGGGACTTCAACCAGAACTTCATCCTGACCGCCCAGGCCTCA
CCCAGCAACACAGTGTGGAAGATCGCAAGTGACTGCTTCCGCTTCCAGGACTGGGCCAGC
TAG
|
Protein Properties |
Number of Residues
| 140 |
Molecular Weight
| 15846.7 |
Theoretical pI
| 4.66 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>NTF2-related export protein 1
MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
PSNTVWKIASDCFRFQDWAS
|
External Links |
GenBank ID Protein
| 5880865 |
UniProtKB/Swiss-Prot ID
| Q9UKK6 |
UniProtKB/Swiss-Prot Entry Name
| NXT1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF156957 |
GeneCard ID
| NXT1 |
GenAtlas ID
| NXT1 |
HGNC ID
| HGNC:15913 |
References |
General References
| Not Available |