Identification
HMDB Protein ID CDBP03705
Secondary Accession Numbers Not Available
Name NTF2-related export protein 1
Description Not Available
Synonyms
  1. Protein p15
Gene Name NXT1
Protein Type Enzyme
Biological Properties
General Function Involved in transport
Specific Function Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5
GO Classification
Component
cell part
intracellular
Process
establishment of localization
transport
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 20p12-p11.2
SNPs NXT1
Gene Sequence
>423 bp
ATGGCATCTGTGGATTTCAAGACCTATGTGGATCAGGCCTGCAGAGCTGCTGAGGAGTTT
GTCAATGTCTACTACACCACCATGGATAAGCGGCGGCGTTTGCTGTCCCGCCTGTACATG
GGCACAGCCACCCTGGTCTGGAATGGCAATGCTGTTTCAGGACAAGAATCCTTGAGTGAG
TTTTTTGAAATGTTGCCTTCCAGCGAGTTCCAAATCAGCGTGGTAGACTGCCAGCCTGTT
CATGATGAAGCCACACCAAGCCAGACCACGGTCCTTGTTGTCATCTGTGGATCAGTGAAG
TTTGAGGGGAACAAACAACGGGACTTCAACCAGAACTTCATCCTGACCGCCCAGGCCTCA
CCCAGCAACACAGTGTGGAAGATCGCAAGTGACTGCTTCCGCTTCCAGGACTGGGCCAGC
TAG
Protein Properties
Number of Residues 140
Molecular Weight 15846.7
Theoretical pI 4.66
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NTF2-related export protein 1
MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
PSNTVWKIASDCFRFQDWAS
GenBank ID Protein 5880865
UniProtKB/Swiss-Prot ID Q9UKK6
UniProtKB/Swiss-Prot Entry Name NXT1_HUMAN
PDB IDs
GenBank Gene ID AF156957
GeneCard ID NXT1
GenAtlas ID NXT1
HGNC ID HGNC:15913
References
General References Not Available