Cannabis Compound Database: Showing Protein Kinesin-like protein KIF20A (CDBP03688)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03688

Secondary Accession Numbers

Not Available

Name

Kinesin-like protein KIF20A

Description

Not Available

Synonyms

GG10_2
Rab6-interacting kinesin-like protein
Rabkinesin-6

Gene Name

KIF20A

Protein Type

Enzyme

Biological Properties

General Function

Involved in microtubule motor activity

Specific Function

Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility

GO Classification

Function
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
binding
catalytic activity
hydrolase activity
motor activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
microtubule motor activity
Process
cellular process
microtubule-based process
microtubule-based movement

Cellular Location

Golgi apparatus

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:5

Locus

5q31

SNPs

KIF20A

Gene Sequence

>2673 bp
ATGTCGCAAGGGATCCTTTCTCCGCCAGCGGGCTTGCTGTCCGATGACGATGTCGTAGTT
TCTCCCATGTTTGAGTCCACAGCTGCAGATTTGGGGTCTGTGGTACGCAAGAACCTGCTA
TCAGACTGCTCTGTCGTCTCTACCTCCCTAGAGGACAAGCAGCAGGTTCCATCTGAGGAC
AGTATGGAGAAGGTGAAAGTATACTTGAGGGTTAGGCCCTTGTTACCTTCAGAGTTGGAA
CGACAGGAAGATCAGGGTTGTGTCCGTATTGAGAATGTGGAGACCCTTGTTCTACAAGCA
CCCAAGGACTCGTTTGCCCTGAAGAGCAATGAACGGGGAATTGGCCAAGCCACACACAGG
TTCACCTTTTCCCAGATCTTTGGGCCAGAAGTGGGACAGGCATCCTTCTTCAACCTAACT
GTGAAGGAGATGGTAAAGGATGTACTCAAAGGGCAGAACTGGCTCATCTATACATATGGA
GTCACTAACTCAGGGAAAACCCACACGATTCAAGGTACCATCAAGGATGGAGGGATTCTC
CCCCGGTCCCTGGCGCTGATCTTCAATAGCCTCCAAGGCCAACTTCATCCAACACCTGAT
CTGAAGCCCTTGCTCTCCAATGAGGTAATCTGGCTAGACAGCAAGCAGATCCGACAGGAG
GAAATGAAGAAGCTGTCCCTGCTAAATGGAGGCCTCCAAGAGGAGGAGCTGTCCACTTCC
TTGAAGAGGAGTGTCTACATCGAAAGTCGGATAGGTACCAGCACCAGCTTCGACAGTGGC
ATTGCTGGGCTCTCTTCTATCAGTCAGTGTACCAGCAGTAGCCAGCTGGATGAAACAAGT
CATCGATGGGCACAGCCAGACACTGCCCCACTACCTGTCCCGGCAAACATTCGCTTCTCC
ATCTGGATCTCATTCTTTGAGATCTACAACGAACTGCTTTATGACCTATTAGAACCGCCT
AGCCAACAGCGCAAGAGGCAGACTTTGCGGCTATGCGAGGATCAAAATGGCAATCCCTAT
GTGAAAGATCTCAACTGGATTCATGTGCAAGATGCTGAGGAGGCCTGGAAGCTCCTAAAA
GTGGGTCGTAAGAACCAGAGCTTTGCCAGCACCCACCTCAACCAGAACTCCAGCCGCAGT
CACAGCATCTTCTCAATCAGGATCCTACACCTTCAGGGGGAAGGAGATATAGTCCCCAAG
ATCAGCGAGCTGTCACTCTGTGATCTGGCTGGCTCAGAGCGCTGCAAAGATCAGAAGAGT
GGTGAACGGTTGAAGGAAGCAGGAAACATTAACACCTCTCTACACACCCTGGGCCGCTGT
ATTGCTGCCCTTCGTCAAAACCAGCAGAACCGGTCAAAGCAGAACCTGGTTCCCTTCCGT
GACAGCAAGTTGACTCGAGTGTTCCAAGGTTTCTTCACAGGCCGAGGCCGTTCCTGCATG
ATTGTCAATGTGAATCCCTGTGCATCTACCTATGATGAAACTCTTCATGTGGCCAAGTTC
TCAGCCATTGCTAGCCAGCTTGTGCATGCCCCACCTATGCAACTGGGATTCCCATCCCTG
CACTCGTTCATCAAGGAACATAGTCTTCAGGTATCCCCCAGCTTAGAGAAAGGGGCTAAG
GCAGACACAGGCCTTGATGATGATATTGAAAATGAAGCTGACATCTCCATGTATGGCAAA
GAGGAGCTCCTACAAGTTGTGGAAGCCATGAAGACACTGCTTTTGAAGGAACGACAGGAA
AAGCTACAGCTGGAGATGCATCTCCGAGATGAAATTTGCAATGAGATGGTAGAACAGATG
CAACAGCGGGAACAGTGGTGCAGTGAACATTTGGACACCCAAAAGGAACTATTGGAGGAA
ATGTATGAAGAAAAACTAAATATCCTCAAGGAGTCACTGACAAGTTTTTACCAAGAAGAG
ATTCAGGAGCGGGATGAAAAGATTGAAGAGCTAGAAGCTCTCTTGCAGGAAGCCAGACAA
CAGTCAGTGGCCCATCAGCAATCAGGGTCTGAATTGGCCCTACGGCGGTCACAAAGGTTG
GCAGCTTCTGCCTCCACCCAGCAGCTTCAGGAGGTTAAAGCTAAATTACAGCAGTGCAAA
GCAGAGCTAAACTCTACCACTGAAGAGTTGCATAAGTATCAGAAAATGTTAGAACCACCA
CCCTCAGCCAAGCCCTTCACCATTGATGTGGACAAGAAGTTAGAAGAGGGCCAGAAGAAT
ATAAGGCTGTTGCGGACAGAGCTTCAGAAACTTGGTGAGTCTCTCCAATCAGCAGAGAGA
GCTTGTTGCCACAGCACTGGGGCAGGAAAACTTCGTCAAGCCTTGACCACTTGTGATGAC
ATCTTAATCAAACAGGACCAGACTCTGGCTGAACTGCAGAACAACATGGTGCTAGTGAAA
CTGGACCTTCGGAAGAAGGCAGCATGTATTGCTGAGCAGTATCATACTGTGTTGAAACTC
CAAGGCCAGGTTTCTGCCAAAAAGCGCCTTGGTACCAACCAGGAAAATCAGCAACCAAAC
CAACAACCACCAGGGAAGAAACCATTCCTTCGAAATTTACTTCCCCGAACACCAACCTGC
CAAAGCTCAACAGACTGCAGCCCTTATGCCCGGATCCTACGCTCACGGCGTTCCCCTTTA
CTCAAATCTGGGCCTTTTGGCAAAAAGTACTAA

Protein Properties

Number of Residues

890

Molecular Weight

100277.1

Theoretical pI

6.91

Pfam Domain Function

Kinesin (PF00225 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Kinesin-like protein KIF20A
MSQGILSPPAGLLSDDDVVVSPMFESTAADLGSVVRKNLLSDCSVVSTSLEDKQQVPSED
SMEKVKVYLRVRPLLPSELERQEDQGCVRIENVETLVLQAPKDSFALKSNERGIGQATHR
FTFSQIFGPEVGQASFFNLTVKEMVKDVLKGQNWLIYTYGVTNSGKTHTIQGTIKDGGIL
PRSLALIFNSLQGQLHPTPDLKPLLSNEVIWLDSKQIRQEEMKKLSLLNGGLQEEELSTS
LKRSVYIESRIGTSTSFDSGIAGLSSISQCTSSSQLDETSHRWAQPDTAPLPVPANIRFS
IWISFFEIYNELLYDLLEPPSQQRKRQTLRLCEDQNGNPYVKDLNWIHVQDAEEAWKLLK
VGRKNQSFASTHLNQNSSRSHSIFSIRILHLQGEGDIVPKISELSLCDLAGSERCKDQKS
GERLKEAGNINTSLHTLGRCIAALRQNQQNRSKQNLVPFRDSKLTRVFQGFFTGRGRSCM
IVNVNPCASTYDETLHVAKFSAIASQLVHAPPMQLGFPSLHSFIKEHSLQVSPSLEKGAK
ADTGLDDDIENEADISMYGKEELLQVVEAMKTLLLKERQEKLQLEMHLRDEICNEMVEQM
QQREQWCSEHLDTQKELLEEMYEEKLNILKESLTSFYQEEIQERDEKIEELEALLQEARQ
QSVAHQQSGSELALRRSQRLAASASTQQLQEVKAKLQQCKAELNSTTEELHKYQKMLEPP
PSAKPFTIDVDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHSTGAGKLRQALTTCDD
ILIKQDQTLAELQNNMVLVKLDLRKKAACIAEQYHTVLKLQGQVSAKKRLGTNQENQQPN
QQPPGKKPFLRNLLPRTPTCQSSTDCSPYARILRSRRSPLLKSGPFGKKY

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

O95235

UniProtKB/Swiss-Prot Entry Name

KI20A_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF070672

GeneCard ID