Cannabis Compound Database: Showing Protein tRNA modification GTPase GTPBP3, mitochondrial (CDBP03654)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03654

Secondary Accession Numbers

Not Available

Name

tRNA modification GTPase GTPBP3, mitochondrial

Description

Not Available

Synonyms

GTP-binding protein 3
Mitochondrial GTP-binding protein 1

Gene Name

GTPBP3

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs (Probable)

GO Classification

Component
cell part
intracellular
Function
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
Process
rna metabolic process
ncrna metabolic process
trna metabolic process
trna processing
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
trna modification

Cellular Location

Mitochondrion

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

19p13.11

SNPs

GTPBP3

Gene Sequence

>1479 bp
ATGTGGCGGGGGCTTTGGACCCTGGCGGCCCAAGCGGCACGTGGGCCTCGCAGATTGTGC
ACGCGCCGGAGCAGCGGCGCACCAGCCCCCGGCTCCGGCGCCACCATCTTCGCGCTAAGC
TCTGGCCAAGGCCGCTGCGGCATCGCAGTGATCCGGACCAGCGGCCCCGCCAGCGGCCAC
GCCCTCCGAATTCTCACAGCACCCCGAGACCTGCCCCTTGCTCGCCACGCCAGCCTGCGC
CTGCTCAGCGATCCCCGCTCCGGGGAGCCTCTGGACCGCGCACTGGTGCTCTGGTTCCCA
GGTCCCCAGAGTTTCACCGGTGAGGACTGCGTGGAGTTCCACGTGCATGGAGGCCCGGCA
GTGGTGAGCGGCGTCCTGCAGGCCTTGGGCAGCGTGCCAGGGCTTCGACCGGCGGAGGCA
GGCGAGTTCACCAGACGGGCGTTCGCCAATGGGAAGCTGAACCTGACCGAAGTGGAGGGG
CTGGCGGACCTTATCCACGCGGAAACAGAGGCGCAGCGGCGGCAGGCCCTCAGGCAGCTG
GACGGAGAGCTGGGCCACCTCTGCCGTGGCTGGGCCGAGACCCTCACCAAAGCTCTGGCC
CACGTGGAGGCCTATATCGATTTCGGCGAGGATGACAACCTGGAGGAGGGGGTCCTGGAG
CAAGCCGACATCGAAGTACGGGCACTGCAGGTGGCCCTGGGTGCACATCTACGAGATGCC
AGGCGCGGGCAGAGGCTCCGCTCAGGGGTGCACGTAGTGGTCACTGGACCCCCCAATGCG
GGCAAGAGCAGCCTAGTGAACCTGCTCAGTCGGAAGCCTGTGTCCATCGTGTCCCCGGAG
CCAGGGACCACCCGTGACGTGCTGGAGACCCCAGTCGACCTGGCCGGATTTCCTGTGCTG
CTGAGCGACACGGCTGGGTTGCGGGAGGGCGTGGGGCCCGTGGAGCAGGAGGGCGTGCGG
CGCGCCCGGGAGAGGCTAGAGCAGGCTGACCTCATTCTGGCCATGCTGGATGCTTCTGAC
CTGGCCTCTCCCTCCAGTTGCAACTTCCTGGCCACCGTCGTAGCCTCTGTGGGAGCCCAG
AGCCCCAGTGACAGCAGCCAGCGCCTCCTCCTGGTGCTGAACAAGTCGGACCTGCTGTCC
CCGGAGGGCCCAGGTCCCGGTCCTGACCTGCCCCCGCACCTGCTGCTGTCCTGTCTGACG
GGAGAGGGGCTGGACGGCCTCCTGGAGGCGCTGAGGAAGGAGCTAGCTGCAGTGTGTGGG
GACCCGTCCACAGATCCCCCGCTGCTGACCCGAGCAAGGCACCAGCACCACCTCCAGGGT
TGCCTGGATGCCCTCGGCCACTACAAGCAGTCAAAAGACCTGGCCCTGGCGGCAGAGGCG
CTGCGGGTGGCCCGGGGTCACCTGACCCGGCTCACAGGTGGAGGGGGTACCGAGGAGATC
CTGGACATCATCTTCCAGGACTTCTGTGTGGGCAAGTGA

Protein Properties

Number of Residues

492

Molecular Weight

52029.5

Theoretical pI

6.46

Pfam Domain Function

MMR_HSR1 (PF01926 )
TrmE_N (PF10396 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>tRNA modification GTPase GTPBP3, mitochondrial
MWRGLWTLAAQAARGPRRLCTRRSSGAPAPGSGATIFALSSGQGRCGIAVIRTSGPASGH
ALRILTAPRDLPLARHASLRLLSDPRSGEPLDRALVLWFPGPQSFTGEDCVEFHVHGGPA
VVSGVLQALGSVPGLRPAEAGEFTRRAFANGKLNLTEVEGLADLIHAETEAQRRQALRQL
DGELGHLCRGWAETLTKALAHVEAYIDFGEDDNLEEGVLEQADIEVRALQVALGAHLRDA
RRGQRLRSGAHVVVTGPPNAGKSSLVNLLSRKPVSIVSPEPGTTRDVLETPVDLAGFPVL
LSDTAGLREGVGPVEQEGVRRARERLEQADLILAMLDASDLASPSSCNFLATVVASVGAQ
SPSDSSQRLLLVLNKSDLLSPEGPGPGPDLPPHLLLSCLTGEGLDGLLEALRKELAAVCG
DPSTDPPLLTRARHQHHLQGCLDALGHYKQSKDLALAAEALRVARGHLTRLTGGGGTEEI
LDIIFQDFCVGK

External Links

GenBank ID Protein

193082991

UniProtKB/Swiss-Prot ID

Q969Y2

UniProtKB/Swiss-Prot Entry Name

GTPB3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_032620.3

GeneCard ID