Identification
HMDB Protein ID CDBP03652
Secondary Accession Numbers Not Available
Name GTP-binding protein 1
Description Not Available
Synonyms
  1. G-protein 1
  2. GP-1
  3. GP1
Gene Name GTPBP1
Protein Type Enzyme
Biological Properties
General Function Involved in GTPase activity
Specific Function Not Available
GO Classification
Function
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q13.1
SNPs GTPBP1
Gene Sequence
>2010 bp
ATGGCGACGGAGCGCAGTCGCTCCGCGATGGACTCGCCGGTCCCGGCCTCTATGTTCGCC
CCCGAGCCCAGCTCCCCGGGGGCGGCCAGGGCCGCGGCGGCCGCCGCCCGACTCCACGGC
GGCTTTGACTCGGACTGCAGCGAGGACGGCGAGGCGCTCAACGGCGAGCCAGAGCTGGAC
CTCACCAGCAAGCTGGTTCTAGTGAGCCCTACATCAGAGCAGTATGACAGCCTACTTCGG
CAGATGTGGGAGAGGATGGACGAGGGATGCGGAGAGACCATATATGTCATTGGGCAGGGA
TCAGATGGGACTGAGTATGGGCTGAGTGAAGCTGACATGGAGGCCTCCTACGCCACAGTG
AAGAGCATGGCGGAACAGATAGAGGCCGATGTCATCCTTCTGCGGGAACGGCAAGAAGCT
GGGGGCCGCGTGCGTGATTACCTGGTCCGGAAACGAGTAGGAGACAATGACTTCCTGGAG
GTCAGGGTAGCAGTGGTGGGCAACGTGGATGCTGGCAAAAGCACGCTTCTGGGGGTCCTG
ACACATGGGGAGCTGGACAATGGCCGAGGCTTTGCCCGCCAGAAACTCTTCCGCCACAAA
CATGAAATTGAATCTGGTCGCACCAGCAGTGTGGGCAACGACATTCTGGGCTTTGACAGT
GAAGGCAATGTAGTGAACAAGCCTGACAGCCACGGCGGCAGCCTGGAGTGGACCAAGATC
TGTGAGAAGTCCACGAAAGTCATTACCTTCATCGACTTGGCTGGTCATGAGAAGTACCTG
AAAACCACTGTCTTCGGCATGACAGGCCATCTGCCTGACTTCTGCATGCTCATGGTGGGC
AGCAATGCTGGCATCGTGGGGATGACCAAAGAACACCTGGGCTTGGCACTGGCACTCAAT
GTACCTGTCTTTGTGGTAGTCACCAAGATTGACATGTGTCCTGCCAACATCCTGCAAGAA
ACCCTGAAGCTGTTACAGCGCCTGCTGAAGTCACCAGGCTGCCGGAAGATCCCCGTGCTG
GTGCAGAGCAAAGATGATGTGATTGTCACAGCCTCCAACTTCAGCTCTGAAAGGATGTGC
CCGATATTCCAGATCTCCAACGTTACAGGCGAGAACCTAGATCTGCTGAAGATGTTCCTC
AACCTCCTCTCCCCCCGCACCAGCTACAGGGAGGAGGAGCCTGCTGAGTTTCAGATTGAT
GACACCTACTCCGTCCCGGGTGTGGGGACAGTGGTTTCGGGGACAACACTGAGAGGCCTG
ATCAAGCTGAATGACACGCTGCTGCTGGGCCCAGACCCCTTGGGTAACTTCCTGTCCATT
GCTGTCAAATCCATCCATCGCAAGCGCATGCCTGTCAAGGAGGTGCGGGGTGGCCAGACA
GCATCCTTTGCGCTGAAGAAGATCAAGCGCTCGTCCATCCGGAAGGGCATGGTGATGGTT
TCCCCACGTTTGAATCCCCAAGCCTCCTGGGAGTTTGAGGCCGAGATTCTCGTCCTCCAC
CACCCCACCACAATTAGCCCGCGCTACCAGGCCATGGTGCACTGTGGGAGCATCAGGCAG
ACAGCCACCATTCTGAGCATGGACAAGGACTGTCTGCGCACTGGGGACAAGGCCACTGTA
CACTTCCGCTTCATCAAGACCCCTGAGTACCTGCACATAGACCAGCGGCTGGTGTTCCGG
GAAGGCCGCACCAAGGCTGTCGGCACCATCACCAAGCTCCTCCAGACCACCAACAACTCC
CCAATGAACTCCAAGCCGCAGCAGATTAAAATGCAGTCGACGAAAAAGGGCCCCCTGACG
AAACGAGACGAGGGGGGCCCGTCTGGTGGGCCAGCAGTAGGAGCACCCCCACCTGGAGAT
GAAGCCTCCTCTGTAGGGGCAGGGCAACCAGCTGCGTCCAGCAATCTCCAGCCTCAGCCT
AAGCCCAGCAGTGGAGGCCGGCGACGAGGGGGCCAGCGCCACAAGGTGAAGTCCCAGGGG
GCCTGTGTGACTCCTGCCAGCGGCTGCTGA
Protein Properties
Number of Residues 669
Molecular Weight 72453.3
Theoretical pI 8.47
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>GTP-binding protein 1
MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELD
LTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATV
KSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVL
THGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKI
CEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALN
VPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMC
PIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGL
IKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMV
SPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATV
HFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLT
KRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQG
ACVTPASGC
GenBank ID Protein 123228951
UniProtKB/Swiss-Prot ID O00178
UniProtKB/Swiss-Prot Entry Name GTPB1_HUMAN
PDB IDs Not Available
GenBank Gene ID AL021707
GeneCard ID GTPBP1
GenAtlas ID GTPBP1
HGNC ID HGNC:4669
References
General References Not Available