| Identification |
|---|
| HMDB Protein ID
| CDBP03647 |
| Secondary Accession Numbers
| Not Available |
| Name
| Guanine nucleotide-binding protein-like 3-like protein |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| GNL3L |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| Required for normal processing of ribosomal pre-rRNA. Required for cell proliferation. Binds GTP |
| GO Classification
|
| Component |
| intracellular |
| cell part |
| Function |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
|
| Cellular Location
|
- Nucleus
- nucleolus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| GNL3L |
| Gene Sequence
|
>1749 bp
ATGATGAAACTTAGACACAAAAATAAAAAGCCAGGTGAAGGTTCCAAGGGCCACAAGAAG
ATAAGTTGGCCCTACCCTCAGCCTGCAAAGCAAAATGGGAAGAAAGCAACCTCCAAAGTG
CCCTCTGCACCTCATTTTGTTCACCCCAATGATCATGCCAATCGAGAGGCTGAATTAAAG
AAGAAGTGGGTTGAGGAGATGAGGGAGAAGCAGCAAGCCGCCCGGGAGCAAGAAAGACAA
AAACGCAGGACCATTGAGAGCTACTGTCAGGATGTCCTAAGACGCCAGGAGGAGTTTGAG
CATAAGGAGGAAGTTTTGCAGGAATTAAATATGTTTCCTCAGCTGGATGACGAGGCCACG
AGGAAGGCTTATTACAAGGAGTTCCGTAAGGTGGTGGAATACTCTGATGTGATTCTGGAA
GTCCTGGATGCCAGAGACCCATTAGGCTGCCGCTGCTTCCAAATGGAGGAGGCTGTCCTG
CGAGCACAAGGCAACAAGAAGCTGGTCCTGGTCTTGAACAAGATTGACCTGGTCCCCAAG
GAGGTTGTGGAGAAATGGCTGGATTACCTTCGGAATGAGTTGCCAACCGTGGCTTTCAAG
GCCAGTACCCAGCATCAGGTCAAAAACCTGAATCGTTGCAGTGTGCCAGTAGATCAGGCC
TCTGAGTCACTGCTGAAAAGCAAAGCCTGCTTTGGAGCTGAAAACCTCATGAGGGTTCTG
GGGAACTATTGCCGCCTTGGTGAAGTGCGCACCCACATTCGTGTGGGTGTTGTGGGTCTT
CCCAATGTTGGGAAGAGCAGCCTGATCAATAGCCTGAAGCGCAGCCGCGCATGCAGCGTG
GGAGCTGTTCCTGGAATTACCAAATTCATGCAGGAGGTCTACCTGGACAAGTTCATCCGG
CTCTTGGATGCTCCAGGCATTGTCCCAGGGCCCAACTCAGAGGTGGGCACCATCCTGCGT
AACTGCGTCCACGTGCAGAAGCTGGCAGACCCTGTGACCCCAGTGGAGACCATCCTGCAG
CGCTGCAACCTGGAGGAGATTTCCAACTATTATGGCGTCTCTGGGTTCCAGACCACTGAG
CACTTTCTGACGGCAGTGGCCCACCGTTTGGGGAAGAAGAAGAAGGGAGGCTTATATAGT
CAGGAACAGGCGGCCAAAGCTGTCCTAGCTGACTGGGTGAGCGGGAAGATCAGCTTCTAT
ATACCACCACCAGCCACTCACACTCTGCCCACCCATCTCAGTGCTGAGATCGTTAAGGAA
ATGACCGAGGTCTTTGACATCGAGGATACTGAGCAGGCCAATGAAGACACCATGGAATGC
TTGGCCACCGGAGAATCTGATGAGCTGTTGGGTGACACGGACCCACTTGAAATGGAGATC
AAGTTGCTCCATTCTCCGATGACGAAAATAGCAGATGCCATTGAAAATAAAACCACCGTG
TATAAGATTGGAGATCTCACTGGGTATTGCACCAATCCAAACCGTCATCAGATGGGGTGG
GCTAAACGCAATGTGGACCACCGCCCTAAGAGCAACAGTATGGTGGATGTCTGCTCAGTG
GACCGCCGCTCAGTGCTGCAGAGGATCATGGAGACGGACCCCCTGCAACAGGGCCAGGCT
CTGGCATCTGCCCTGAAAAATAAGAAGAAGATGCAGAAACGTGCAGATAAAATCGCCAGC
AAGCTGTCTGATTCCATGATGTCTGCTCTCGACCTCTCTGGCAATGCTGATGATGGTGTT
GGTGACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 582 |
| Molecular Weight
| 65572.7 |
| Theoretical pI
| 8.62 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Guanine nucleotide-binding protein-like 3-like protein
MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELK
KKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEAT
RKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPK
EVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVL
GNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIR
LLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTE
HFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKE
MTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTV
YKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQA
LASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD
|
| External Links |
|---|
| GenBank ID Protein
| 7022755 |
| UniProtKB/Swiss-Prot ID
| Q9NVN8 |
| UniProtKB/Swiss-Prot Entry Name
| GNL3L_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK001475 |
| GeneCard ID
| GNL3L |
| GenAtlas ID
| GNL3L |
| HGNC ID
| HGNC:25553 |
| References |
|---|
| General References
| Not Available |