| Identification |
|---|
| HMDB Protein ID
| CDBP03643 |
| Secondary Accession Numbers
| Not Available |
| Name
| GTPase IMAP family member 8 |
| Description
| Not Available |
| Synonyms
|
- IAN-9
- Immune-associated nucleotide-binding protein 9
- Protein IanT
|
| Gene Name
| GIMAP8 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections |
| GO Classification
|
| Function |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
|
| Cellular Location
|
- Mitochondrion
- Golgi apparatus
- Endoplasmic reticulum
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q36.1 |
| SNPs
| GIMAP8 |
| Gene Sequence
|
>1998 bp
ATGTCAGAGCAGAGCTGCCAGATGTCCGAACTGCGGCTCCTCCTCCTGGGGAAATGCCGC
TCGGGAAAAAGTGCCACAGGAAATGCCATTCTGGGCAAACATGTGTTCAAGTCCAAGTTC
AGTGATCAGACAGTGATCAAAATGTGCCAGAGAGAGAGTTGGGTCCTGAGAGAAAGGAAG
GTTGTGGTAATTGACACCCCTGACCTTTTCTCCTCAATAGCTTGTGCTGAAGACAAGCAA
CGCAACATCCAACACTGCTTGGAGCTCTCTGCTCCCAGCCTCCATGCTCTGCTCTTGGTA
ATTGCCATCGGCCATTTCACAAGGGAGGATGAGGAAACAGCCAAGGGCATCCAACAAGTG
TTTGGAGCTGAAGCCAGGAGGCACATCATTATTGTCTTCACTCGGAAGGATGATTTGGGG
GATGACTTGCTGCAAGATTTCATTGAAAAAAACAAACCTCTCAAGCAGTTGGTTCAAGAC
TATGAGGGCCGATACTGCATTTTCAACAACAAGACCAATAGTAAGGATGAGCAGATCACC
CAGGTGTTGGAGCTCCTTCGCAAGGTTGAGTCTTTGGTGAATACGAACGGAGGACCCTAT
CATGTGAACTTCAAAACTGAAGGCAGCAGGTTTCAAGATTGTGTGAATGAAGCTGCATCT
CAAGAGGGAGACAAGCCACAGGGCCCAAGGGAAAGGCAGCTGCAGTCCACAGGACCCGAG
CAGAATCCGGGGACATCAGAACTGACAGTCCTCCTTGTGGGGAAACGCGGTGCTGGAAAA
AGTGCAGCAGGAAACAGCATTCTGGGGAGGCAGGCCTTTCAGACCGGATTTAGTGAGCAG
TCAGTAACCCAGAGCTTCTTGTCTGAGAGCAGAAGCTGGAGAAAAAAGAAAGTTTCGATC
ATTGATGCTCCGGACATCTCATCTTTAAAGAACATTGACTCAGAAGTTAGAAAACACATC
TGTACAGGCCCCCATGCCTTCCTGCTGGTGACACCACTGGGCTTTTACACTAAGAATGAT
GAGGCAGTGCTGAGCACCATCCAAAACAATTTTGGAGAAAAATTCTTTGAGTACATGATC
ATACTTCTTACCAGGAAAGAAGATTTAGGGGATCAGGATCTAGATACGTTCTTAAGAAAC
AGCAATAAAGCTCTCTATGGTCTCATCCAGAAGTGTAAAAACAGATATAGTGCCTTCAAC
TACCGGGCAACAGGAGAAGAAGAGCAAAGGCAGGCGGACGAGCTCCTGGAAAAAATTGAG
AGCATGGTGCATCAGAATGGGAACAAGCATTGCGTTTTCAGAGAAAAAGAAACCCTGAAC
ATTGTCCTTGTGGGGAGAAGCGGGACTGGGAAGAGTGCGACCGGGAACTCTATCCTGGGG
AGCCTCGTCTTCACCTCTCGGCTCCGGGCCCAGCCAGTCACCAAGACCAGCCAGAGTGGC
AGGAGGACATGGGACGGACAGGAGGTGGTGGTTGTGGACACTCCTTCCTTCAACCAGATG
CTGGATGTCGAAAAGGACCCATCCCGGTTAGAAGAGGAGGTCAAGCGCTGTTTGTCCTGC
TGTGAAAAAGGGGACACATTTTTTGTCCTGGTGTTCCAGCTGGGACGATTCACTGAAGAG
GACAAAACAGCTGTGGCGAAACTGGAGGCCATCTTTGGAGCAGACTTTACGAAATACGCG
ATTATGCTGTTCACCCGGAAGGAAGACCTAGGGGCGGGGAATTTGGAAGACTTCATGAAG
AACTCAGATAACAAAGCCCTTCGGCGCATTTTTAAAAAGTGTGGGCGGCGAGTTTGTGCT
TTTAACAACAAAGAAACAGGCCAGGCCCAGGAAACCCAGGTGAAAGCTCTTTTAACAAAG
GTCAATGATCTGAGAAAAGAAAGTGGGTGGTCCGGGTATCCCCATACACAGGAGAACGTC
AGCAAACTAATTAAAAATGTCCAGGAAATGTCCCAAGCCGAAAAACTCCTTAAAAATTTA
ATAGGTATTTTACAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 665 |
| Molecular Weight
| 74889.6 |
| Theoretical pI
| 8.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>GTPase IMAP family member 8
MSEQSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKFSDQTVIKMCQRESWVLRERK
VVVIDTPDLFSSIACAEDKQRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQQV
FGAEARRHIIIVFTRKDDLGDDLLQDFIEKNKPLKQLVQDYEGRYCIFNNKTNSKDEQIT
QVLELLRKVESLVNTNGGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRERQLQSTGPE
QNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQTGFSEQSVTQSFLSESRSWRKKKVSI
IDAPDISSLKNIDSEVRKHICTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFGEKFFEYMI
ILLTRKEDLGDQDLDTFLRNSNKALYGLIQKCKNRYSAFNYRATGEEEQRQADELLEKIE
SMVHQNGNKHCVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLRAQPVTKTSQSG
RRTWDGQEVVVVDTPSFNQMLDVEKDPSRLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEE
DKTAVAKLEAIFGADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKALRRIFKKCGRRVCA
FNNKETGQAQETQVKALLTKVNDLRKESGWSGYPHTQENVSKLIKNVQEMSQAEKLLKNL
IGILQ
|
| External Links |
|---|
| GenBank ID Protein
| 77680753 |
| UniProtKB/Swiss-Prot ID
| Q8ND71 |
| UniProtKB/Swiss-Prot Entry Name
| GIMA8_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ633686 |
| GeneCard ID
| GIMAP8 |
| GenAtlas ID
| GIMAP8 |
| HGNC ID
| HGNC:21792 |
| References |
|---|
| General References
| Not Available |