Cannabis Compound Database: Showing Protein ADP-ribosylation factor-binding protein GGA3 (CDBP03636)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03636

Secondary Accession Numbers

Not Available

Name

ADP-ribosylation factor-binding protein GGA3

Description

Not Available

Synonyms

Golgi-localized, gamma ear-containing, ARF-binding protein 3

Gene Name

GGA3

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein binding

Specific Function

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif

GO Classification

Component
clathrin adaptor complex
membrane coat
golgi apparatus part
cell part
intracellular part
macromolecular complex
protein complex
cytoplasmic part
ap-type membrane coat adaptor complex
intracellular
Function
binding
protein binding
Process
establishment of localization
transport
protein transport
intracellular protein transport
vesicle-mediated transport

Cellular Location

Peripheral membrane protein
Peripheral membrane protein
Endosome membrane
Golgi apparatus
trans-Golgi network membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

17q25.1

SNPs

GGA3

Gene Sequence

>2172 bp
ATGGCGGAGGCGGAAGGGGAAAGCCTGGAGTCCTGGCTCAATAAAGCCACCAATCCTTCC
AACCGCCAGGAGGACTGGGAATACATAATTGGCTTCTGTGATCAGATCAACAAGGAGCTG
GAAGGGCCACAGATCGCCGTCCGACTGCTGGCCCACAAGATCCAGTCCCCACAGGAATGG
GAGGCGCTCCAGGCCCTGACGGTGCTGGAGGCATGCATGAAGAACTGTGGGAGGAGATTT
CATAACGAAGTGGGGAAGTTCCGCTTTTTGAATGAGTTAATCAAAGTCGTCTCTCCAAAG
TACCTGGGGGACAGGGTGTCTGAGAAAGTGAAGACCAAGGTTATTGAGCTGCTGTACAGC
TGGACCATGGCCCTGCCAGAAGAAGCAAAGATCAAAGACGCCTACCACATGCTGAAGAGA
CAGGGCATAGTGCAGTCTGACCCACCAATTCCTGTGGATAGGACGCTGATCCCCTCTCCA
CCACCTCGTCCCAAAAACCCTGTTTTTGATGATGAGGAGAAGTCCAAGCTTTTAGCCAAG
CTGCTGAAAAGCAAAAACCCAGATGACCTGCAGGAGGCCAACAAGCTCATCAAGTCCATG
GTGAAGGAAGACGAGGCACGGATCCAGAAGGTGACCAAGCGTCTGCACACGTTAGAGGAA
GTTAACAACAACGTGAGACTGCTCAGTGAGATGCTGCTTCATTACAGCCAGGAGGACTCT
TCGGACGGGGACAGAGAGCTGATGAAGGAGCTGTTTGATCAGTGTGAGAACAAGAGGCGG
ACTTTATTTAAACTCGCCAGTGAGACTGAGGACAATGATAACAGTTTGGGGGACATCCTG
CAAGCCAGTGACAACCTCTCCCGGGTCATCAACTCTTACAAAACAATTATTGAAGGGCAG
GTCATCAATGGCGAGGTGGCTACCTTAACCCTGCCTGACTCGGAAGGAAACAGTCAGTGC
AGTAACCAAGGCACGCTCATCGACCTTGCGGAGCTGGACACGACCAACAGTTTGTCCTCC
GTGTTGGCCCCAGCACCTACTCCACCCTCCTCAGGCATCCCAATCCTCCCTCCACCACCC
CAGGCCTCAGGACCTCCACGGAGCCGCTCCTCTAGCCAGGCCGAGGCCACCCTGGGGCCC
AGCAGCACAAGCAACGCCCTCTCCTGGCTGGACGAGGAGCTACTCTGCTTGGGCCTCGCC
GACCCAGCCCCTAATGTTCCTCCCAAAGAGTCAGCTGGGAACAGCCAGTGGCACCTGCTC
CAGAGGGAACAGTCCGACCTGGACTTCTTCAGCCCCAGGCCGGGGACCGCTGCCTGTGGC
GCCTCCGATGCTCCTCTGCTCCAGCCCTCAGCCCCCTCCTCAAGCAGCTCCCAAGCTCCA
CTGCCGCCTCCCTTCCCAGCTCCTGTGGTCCCAGCCAGTGTTCCTGCCCCCAGTGCGGGC
TCCTCCTTGTTTTCTACTGGAGTGGCCCCAGCCTTGGCCCCAAAAGTTGAGCCCGCAGTC
CCTGGGCACCATGGCTTGGCGTTGGGCAACAGCGCGCTGCACCACCTGGATGCCCTCGAT
CAGCTTCTAGAAGAGGCCAAAGTGACCTCGGGCTTGGTGAAACCCACTACCTCCCCTCTC
ATCCCCACCACCACCCCAGCCAGGCCCCTCCTGCCCTTCTCCACGGGGCCCGGCAGCCCG
CTCTTCCAGCCACTGAGTTTCCAGTCCCAGGGCAGCCCCCCGAAGGGGCCTGAGCTCTCC
CTGGCCAGCATCCACGTGCCCCTGGAATCGATCAAGCCTAGCAGTGCCCTTCCTGTGACA
GCCTACGATAAAAACGGCTTCCGCATCCTCTTCCACTTTGCCAAGGAGTGTCCCCCAGGA
CGACCTGACGTGCTGGTGGTGGTGGTGTCCATGCTGAACACGGCTCCCTTACCTGTCAAG
AGCATCGTGCTGCAGGCTGCAGTGCCCAAGTCAATGAAAGTGAAGTTGCAGCCACCTTCT
GGGACAGAACTCTCTCCATTTAGCCCCATCCAGCCACCTGCAGCCATCACCCAGGTCATG
TTGCTGGCCAATCCACTGAAGGAGAAGGTGCGGCTTCGGTATAAGCTGACCTTCGCCCTG
GGGGAGCAGCTGAGCACAGAGGTGGGCGAGGTGGACCAGTTCCCTCCTGTGGAACAGTGG
GGGAACCTATGA

Protein Properties

Number of Residues

723

Molecular Weight

78314.5

Theoretical pI

5.27

Pfam Domain Function

Alpha_adaptinC2 (PF02883 )
GAT (PF03127 )
VHS (PF00790 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>ADP-ribosylation factor-binding protein GGA3
MAEAEGESLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEW
EALQALTVLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYS
WTMALPEEAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAK
LLKSKNPDDLQEANKLIKSMVKEDEARIQKVTKRLHTLEEVNNNVRLLSEMLLHYSQEDS
SDGDRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQ
VINGEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPP
QASGPPRSRSSSQAEATLGPSSTSNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLL
QREQSDLDFFSPRPGTAACGASDAPLLQPSAPSSSSSQAPLPPPFPAPVVPASVPAPSAG
SSLFSTGVAPALAPKVEPAVPGHHGLALGNSALHHLDALDQLLEEAKVTSGLVKPTTSPL
IPTTTPARPLLPFSTGPGSPLFQPLSFQSQGSPPKGPELSLASIHVPLESIKPSSALPVT
AYDKNGFRILFHFAKECPPGRPDVLVVVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPS
GTELSPFSPIQPPAAITQVMLLANPLKEKVRLRYKLTFALGEQLSTEVGEVDQFPPVEQW
GNL

External Links

GenBank ID Protein

20336267

UniProtKB/Swiss-Prot ID

Q9NZ52

UniProtKB/Swiss-Prot Entry Name

GGA3_HUMAN

PDB IDs