Cannabis Compound Database: Showing Protein ADP-ribosylation factor-binding protein GGA1 (CDBP03634)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03634

Secondary Accession Numbers

Not Available

Name

ADP-ribosylation factor-binding protein GGA1

Description

Not Available

Synonyms

Gamma-adaptin-related protein 1
Golgi-localized, gamma ear-containing, ARF-binding protein 1

Gene Name

GGA1

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein binding

Specific Function

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif

GO Classification

Component
protein complex
cytoplasmic part
ap-type membrane coat adaptor complex
intracellular
clathrin adaptor complex
membrane coat
golgi apparatus part
cell part
intracellular part
macromolecular complex
Function
binding
protein binding
Process
establishment of localization
transport
protein transport
intracellular protein transport
vesicle-mediated transport

Cellular Location

Peripheral membrane protein
Peripheral membrane protein
Endosome membrane
Golgi apparatus
trans-Golgi network membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:2

Locus

22q13.31

SNPs

GGA1

Gene Sequence

>1920 bp
ATGGAGCCCGCGATGGAGCCGGAGACTCTGGAGGCGCGAATCAATAGAGCCACGAACCCC
CTGAACAAGGAGCTCGACTGGGCCAGCATCAACGGCTTCTGCGAGCAGCTCAACGAGGAC
TTTGAGGGGCCTCCACTCGCCACCCGGCTGCTGGCCCACAAGATCCAGTCCCCACAGGAG
TGGGAGGCGATCCAGGCCTTGACGGTGCTGGAAACATGCATGAAGAGCTGCGGCAAGCGG
TTCCACGACGAAGTGGGCAAGTTCCGCTTTCTCAACGAGCTCATCAAGGTCGTGTCTCCC
AAGTATCTGGGCTCTCGGACATCGGAGAAGGTGAAGAACAAGATCTTGGAGCTCCTCTAC
AGCTGGACAGTGGGCCTGCCCGAGGAGGTGAAAATCGCAGAGGCCTACCAGATGCTAAAG
AAGCAGGGGATTGTAAAGTCCGACCCCAAGCTTCCAGATGACACTACCTTTCCCCTTCCT
CCTCCACGGCCGAAGAATGTGATCTTTGAAGATGAGGAGAAATCCAAGATGCTGGCCCGC
CTGCTGAAGAGCTCCCATCCCGAAGACCTCCGCGCAGCCAATAAGCTCATCAAAGAGATG
GTGCAGGAGGACCAGAAGCGGATGGAGAAGATCTCGAAGAGGGTGAATGCCATCGAGGAG
GTGAACAACAATGTGAAACTGCTCACGGAGATGGTGATGAGCCACAGCCAGGGCGGCGCA
GCAGCTGGCAGCAGCGAGGACCTCATGAAGGAACTGTACCAGCGCTGTGAGCGGATGCGG
CCCACGCTCTTCCGACTGGCGAGTGACACAGAGGACAATGATGAGGCCTTAGCGGAGATC
CTGCAGGCCAATGACAACCTCACCCAGGTGATCAACCTGTATAAGCAGCTGGTGCGGGGT
GAGGAGGTCAACGGTGATGCCACAGCCGGCTCCATCCCTGGGAGCACCTCGGCCCTGCTG
GATCTCTCAGGCCTGGATCTCCCGCCTGCGGGCACCACCTACCCAGCTATGCCCACCCGC
CCTGGCGAGCAGGCCAGCCCTGAGCAACCCAGTGCCTCAGTTTCCCTGCTTGACGACGAG
CTCATGTCTCTGGGCCTCAGTGACCCCACACCCCCTTCAGGCCCAAGCCTGGATGGTACC
GGATGGAACAGCTTCCAGTCGTCGGATGCCACTGAGCCCCCAGCCCCTGCTCTGGCCCAG
GCCCCCAGTATGGAAAGCCGACCCCCAGCGCAGACATCCCTGCCAGCAAGCAGCGGTCTG
GACGACCTAGACCTCCTGGGGAAGACCCTCCTGCAGCAGTCGCTGCCCCCGGAATCCCAG
CAAGTGCGGTGGGAGAAGCAGCAGCCAACCCCCCGGCTCACACTCCGGGACCTGCAGAAT
AAGAGCAGCAGCTGCAGCTCCCCCAGCTCCAGCGCCACCAGCCTTCTCCACACCGTGTCC
CCAGAGCCCCCCAGGCCTCCGCAGCAGCCCGTACCAACCGAGCTCTCACTGGCCAGCATC
ACTGTGCCCCTGGAGTCCATCAAACCCAGCAACATCCTGCCCGTGACTGTGTATGACCAG
CACGGCTTCCGCATCCTCTTCCATTTTGCCCGGGACCCACTGCCAGGGCGCTCCGACGTG
CTGGTGGTGGTGGTTTCCATGCTGAGCACCGCCCCCCAGCCCATCCGCAACATCGTGTTC
CAGTCAGCTGTCCCCAAGGTTATGAAGGTGAAGCTGCAGCCACCCTCGGGCACGGAGCTG
CCAGCTTTTAACCCCATCGTCCACCCCTCAGCAATCACCCAGGTCCTGCTGCTTGCCAAC
CCCCAGAAGGAGAAGGTTCGCCTCCGCTACAAGCTCACCTTCACCATGGGTGACCAGACC
TACAACGAGATGGGGGATGTGGACCAGTTCCCCCCACCTGAAACCTGGGGTAGCCTCTAG

Protein Properties

Number of Residues

639

Molecular Weight

70383.5

Theoretical pI

4.93

Pfam Domain Function

Alpha_adaptinC2 (PF02883 )
GAT (PF03127 )
VHS (PF00790 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>ADP-ribosylation factor-binding protein GGA1
MEPAMEPETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQE
WEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLY
SWTVGLPEEVKIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLAR
LLKSSHPEDLRAANKLIKEMVQEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGGA
AAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRG
EEVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDE
LMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL
DDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVS
PEPPRPPQQPVPTELSLASITVPLESIKPSNILPVTVYDQHGFRILFHFARDPLPGRSDV
LVVVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLAN
PQKEKVRLRYKLTFTMGDQTYNEMGDVDQFPPPETWGSL

External Links

GenBank ID Protein

6179912

UniProtKB/Swiss-Prot ID

Q9UJY5

UniProtKB/Swiss-Prot Entry Name

GGA1_HUMAN

PDB IDs