Identification |
HMDB Protein ID
| CDBP03633 |
Secondary Accession Numbers
| Not Available |
Name
| Guanylate-binding protein 7 |
Description
| Not Available |
Synonyms
|
- GBP-7
- GTP-binding protein 7
- Guanine nucleotide-binding protein 7
- Guanylate-binding protein 4-like
|
Gene Name
| GBP7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTPase activity |
Specific Function
| Binds GTP, GDP and GMP |
GO Classification
|
Function |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
pyrophosphatase activity |
purine nucleotide binding |
binding |
nucleotide binding |
catalytic activity |
hydrolase activity |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
gtpase activity |
nucleoside-triphosphatase activity |
hydrolase activity, acting on acid anhydrides |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1p22.2 |
SNPs
| GBP7 |
Gene Sequence
|
>1917 bp
ATGGCATCAGAGATCCACATGCCAGGCCCAGTGTGCCTCACTGAGAACACTAAAGGGCAT
CTGGTGGTGAATTCAGAAGCTCTGGAAATCCTGTCTGCCATTACACAGCCTGTAGTAGTG
GTGGCAATTGTGGGCCTCTACCGCACAGGCAAATCCTACCTAATGAACAAGCTGGCTGGG
AAGAACAAAGGCTTCCCTCTGGGCTGCACAGTGAAGTCTGAAACCAAAGGCATCTGGATG
TGGTGTGTGCCCCACCCCTCCAAGCCAAACCACACCCTGATCCTTCTGGACACGGAGGGC
CTGGGTGATATGGAAAAGAGTGACCCTAAGAGTGACTCGTGGATCTTTGCCCTGGCTGTG
CTTCTAAGCAGCAGCTTTGTCTACAACAGCATGGGCACCATCAACCACCAGGCCCTGGAG
CAGCTGCACTACGTGACTGAGCTAACAGAGCTAATCAGGGCAAAATCGTGCCCCAGACCT
GATGAAGTTGAGGACTCCAGCGAGTTTGTGAGTTTCTTTCCAGACTTTATTTGGACTGTT
CGAGATTTTACCCTGGAGCTGAAGTTAGATGGACACCCCATCACAGAAGATGAGTACCTG
GAGAATGCCTTGAAGCTGATTTCAGGCAAGAATCCCCAAATCCAAAATTCTAACAAGCCC
AGGGAGTGGATCAGGCATTTCTTTCCAAAACAGAAGTGCTTTGTCTTTGACCGGCCAATA
AATGACAAAAAACTCTTACTCCATGTTGAAGAAGTACGAGAAGACCAACTGGATAGTAAT
TTCCAGATGCAATCAGAAAATTTCTGTTCTTATATCTTCACCCATGCAAAGACCAAGACC
CTGAGAGAGGGAATCCTTGTCACTGGAAACCGGCTGGGGATGCTGGTGGAGACCTACCTG
GATGCCATCAACAGTGGAGCGACTCCTTGTCTGGAGAATGCAATGGCAGTTCTGGCCCAG
TGTGAGAACTCAGCAGCCGTGCAGAGGGCAGCCAACCACTACAGCCAGCAGATGGCCCAG
CAAGTGAGATTCCCCACAGACACACTCCAGGAGCTGCTGGACGTGCATGCAGTTTGTGAG
AGGGAAGCCATTGCAGTCTTCATGGAGTACTCCTTCAAAGATAAAAGCCAGGAATTTCAG
AAGAAGCTTGTGGACACCATGGAGAAAAAGAAGGAAGACTTTGTGCTGCAGAATGAAGAG
GCATCTGCCAAATATTGTCAGGCTGAGCTTAAGCGGCTTTCAGAGCTCTTGACAGAAAGT
ATTTCAAGAGGAACTTTCTTTGTTCCGGGGGGGCACAATATCTACTTAGAAGCAAAAAAG
AAGATTGAACAGGACTATACACTAGTGCCCAGAAAAGGAGTTAAGGCAGACGAGGTCCTC
CAGAGCTTCCTGCAGTCACAGGTGGTTATAGAGGAATCCATCCTGCAGTCAGACAAAGCC
CTCACTGCTGGAGAGAAGGCCATAGCAGCTAAGCAGGCTAAGAAGGAGGCAGCTGAAAAG
GAACAGGAGCTGCTAAGACAAAAACAGAAGGAACAGCAGCAAATGATGGAGGCTCAAGAG
AGAAGTTTCCAGGAAAACATAGCTCAACTCAAGAAGAAGATGGAGAGGGAAAGGGAAAAC
TATATGAGAGAACTGAGAAAGATGTTGAGTCACAAGATGAAGGTCCTAGAAGAACTGCTT
ACTGAAGGATTTAAAGAGATATTTGAGTCGTTAAATGAAGAGATTAATCGACTGAAAGAA
CAAATTGAAGCAGCTGAAAATGAAGAGCCCTCAGTGTTTTCACAGATTCTTGATGTGGCT
GGCAGTATATTTATTGCAGCACTACCTGGGGCTGCTAAGCTAGTTGATTTAGGAATGAAA
ATTCTTAGCTCATTATGTAATAGGCTGAGAAATCCTGGTAAGAAAATTATAAGCTGA
|
Protein Properties |
Number of Residues
| 638 |
Molecular Weight
| 72524.7 |
Theoretical pI
| 5.84 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Guanylate-binding protein 7
MASEIHMPGPVCLIENTKGHLVVNSEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAG
KNKGFPLGCTVKSETKGIWMWCVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAV
LLSSSFVYNSMGTINHQALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTV
RDFTLELKLDGHPITEDEYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPI
NDKKLLLHVEEVREDQLDSNFQMQSENFCSYIFTHAKTKTLREGILVTGNRLGMLVETYL
DAINSGATPCLENAMAVLAQCENSAAVQRAANHYSQQMAQQVRFPTDTLQELLDVHAVCE
REAIAVFMEYSFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKYCQAELKRLSELLTES
ISRGTFFVPGGHNIYLEAKKKIEQDYTLVPRKGVKADEVLQSFLQSQVVIEESILQSDKA
LTAGEKAIAAKQAKKEAAEKEQELLRQKQKEQQQMMEAQERSFQENIAQLKKKMEREREN
YMRELRKMLSHKMKVLEELLTEGFKEIFESLNEEINRLKEQIEAAENEEPSVFSQILDVA
GSIFIAALPGAAKLVDLGMKILSSLCNRLRNPGKKIIS
|
External Links |
GenBank ID Protein
| 148234215 |
UniProtKB/Swiss-Prot ID
| Q8N8V2 |
UniProtKB/Swiss-Prot Entry Name
| GBP7_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_207398.2 |
GeneCard ID
| GBP7 |
GenAtlas ID
| GBP7 |
HGNC ID
| HGNC:29606 |
References |
General References
| Not Available |