Cannabis Compound Database: Showing Protein Guanylate-binding protein 4 (CDBP03631)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03631

Secondary Accession Numbers

Not Available

Name

Guanylate-binding protein 4

Description

Not Available

Synonyms

GBP-4
GTP-binding protein 4
Guanine nucleotide-binding protein 4

Gene Name

GBP4

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTPase activity

Specific Function

Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation

GO Classification

Function
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity

Cellular Location

Cytoplasm

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1p22.2

SNPs

GBP4

Gene Sequence

>1923 bp
ATGGGTGAGAGAACTCTTCACGCTGCAGTGCCCACACCAGGTTATCCAGAATCTGAATCC
ATCATGATGGCCCCCATTTGTCTAGTGGAAAACCAGGAAGAGCAGCTGACAGTGAATTCA
AAGGCATTAGAGATTCTTGACAAGATTTCTCAGCCCGTGGTGGTGGTGGCCATTGTAGGG
CTATACCGCACAGGAAAATCCTATCTCATGAATCGTCTTGCAGGAAAGCGCAATGGCTTC
CCTCTGGGCTCCACGGTGCAGTCTGAAACTAAGGGCATCTGGATGTGGTGTGTGCCCCAC
CTCTCTAAGCCAAACCACACCCTGGTCCTTCTGGACACCGAGGGCCTGGGCGATGTAGAA
AAGAGTAACCCTAAGAATGACTCGTGGATCTTTGCCCTGGCTGTGCTTCTAAGCAGCAGC
TTTGTCTATAACAGCGTGAGCACCATCAACCACCAGGCCCTGGAGCAGCTGCACTATGTG
ACTGAGCTAGCAGAGCTAATCAGGGCAAAATCCTGCCCCAGACCTGATGAAGCTGAGGAC
TCCAGCGAGTTTGCGAGTTTCTTTCCAGACTTTATTTGGACTGTTCGGGATTTTACCCTG
GAGCTAAAGTTAGATGGAAACCCCATCACAGAAGATGAGTACCTGGAGAATGCCTTGAAG
CTGATTCCAGGCAAGAATCCCAAAATTCAAAATTCAAACATGCCTAGAGAGTGTATCAGG
CATTTCTTCCGAAAACGGAAGTGCTTTGTCTTTGACCGGCCTACAAATGACAAGCAATAT
TTAAATCATATGGACGAAGTGCCAGAAGAAAATCTGGAAAGGCATTTCCTTATGCAATCA
GACAACTTCTGTTCTTATATCTTCACCCATGCAAAGACCAAGACCCTGAGAGAGGGAATC
ATTGTCACTGGAAAGCGGCTGGGGACTCTGGTGGTGACTTATGTAGATGCCATCAACAGT
GGAGCAGTACCTTGTCTGGAGAATGCAGTGACAGCACTGGCCCAGCTTGAGAACCCAGCG
GCTGTGCAGAGGGCAGCCGACCACTATAGCCAGCAGATGGCCCAGCAACTGAGGCTCCCC
ACAGACACGCTCCAGGAGCTGCTGGACGTGCATGCAGCCTGTGAGAGGGAAGCCATTGCA
GTCTTCATGGAGCACTCCTTCAAGGATGAAAACCATGAATTCCAGAAGAAGCTTGTGGAC
ACCATAGAGAAAAAGAAGGGAGACTTTGTGCTGCAGAATGAAGAGGCATCTGCCAAATAT
TGCCAGGCTGAGCTTAAGCGGCTTTCAGAGCACCTGACAGAAAGCATTTTGAGAGGAATT
TTCTCTGTTCCTGGAGGACACAATCTCTACTTAGAAGAAAAGAAACAGGTTGAGTGGGAC
TATAAGCTAGTGCCCAGAAAAGGAGTTAAGGCAAACGAGGTCCTCCAGAACTTCCTGCAG
TCACAGGTGGTTGTAGAGGAATCCATCCTGCAGTCAGACAAAGCCCTCACTGCTGGAGAG
AAGGCCATAGCAGCGGAGCGGGCCATGAAGGAAGCAGCTGAGAAGGAACAGGAGCTGCTA
AGAGAAAAACAGAAGGAGCAGCAGCAAATGATGGAGGCTCAAGAGAGAAGCTTCCAGGAA
AACATAGCTCAACTCAAGAAGAAGATGGAGAGGGAAAGGGAAAACCTTCTCAGAGAGCAT
GAAAGGCTGCTAAAACACAAGCTGAAGGTACAAGAAGAAATGCTTAAGGAAGAATTTCAA
AAGAAATCTGAGCAGTTAAATAAAGAGATTAATCAACTGAAAGAAAAAATTGAAAGCACT
AAAAATGAACAGTTAAGGCTCTTAAAGATCCTTGACATGGCTAGCAACATAATGATTGTC
ACTCTACCTGGGGCTTCCAAGCTACTTGGAGTAGGGACAAAATATCTTGGCTCACGTATT
TAA

Protein Properties

Number of Residues

640

Molecular Weight

73164.2

Theoretical pI

5.89

Pfam Domain Function

GBP (PF02263 )
GBP_C (PF02841 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Guanylate-binding protein 4
MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVG
LYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVE
KSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAED
SSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIR
HFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGI
IVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLP
TDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKY
CQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQ
SQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQE
YMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIEST
KNEQLRLLKILDMASNIMIVTLPGASKLLGVGTKYLGSRI

External Links

GenBank ID Protein

15558943

UniProtKB/Swiss-Prot ID

Q96PP9

UniProtKB/Swiss-Prot Entry Name

GBP4_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF288814

GeneCard ID