Cannabis Compound Database: Showing Protein Guanylate-binding protein 3 (CDBP03630)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP03630

Secondary Accession Numbers

Not Available

Name

Guanylate-binding protein 3

Description

Not Available

Synonyms

GBP-3
GTP-binding protein 3
Guanine nucleotide-binding protein 3

Gene Name

GBP3

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTPase activity

Specific Function

Binds GTP, GDP and GMP

GO Classification

Function
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity

Cellular Location

Membrane
Multi-pass membrane protein (Potential)

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1p22.2

SNPs

GBP3

Gene Sequence

>1788 bp
ATGGCTCCAGAGATCCACATGACAGGCCCAATGTGCCTCATTGAGAACACTAATGGGGAA
CTGGTGGCGAATCCAGAAGCTCTGAAAATCCTGTCTGCCATTACACAGCCTGTGGTGGTG
GTGGCAATTGTGGGCCTCTACCGCACAGGAAAATCCTACCTGATGAACAAGCTAGCTGGG
AAGAATAAGGGCTTCTCTCTGGGCTCCACAGTGAAATCTCACACCAAAGGAATCTGGATG
TGGTGTGTGCCTCACCCCAAAAAGCCAGAACACACCTTAGTCCTGCTTGACACTGAGGGC
CTGGGAGATGTAAAGAAGGGTGACAACCAGAATGACTCCTGGATCTTCACCCTGGCCGTC
CTCCTGAGCAGCACTCTCGTGTACAATAGCATGGGAACCATCAACCAGCAGGCTATGGAC
CAACTGTACTATGTGACAGAGCTGACACATCGAATCCGATCAAAATCCTCACCTGATGAG
AATGAGAATGAGGATTCAGCTGACTTTGTGAGCTTCTTCCCAGATTTTGTGTGGACACTG
AGAGATTTCTCCCTGGACTTGGAAGCAGATGGACAACCCCTCACACCAGATGAGTACCTG
GAGTATTCCCTGAAGCTAACGCAAGGTACCAGTCAAAAAGATAAAAATTTTAATCTGCCC
CGACTCTGTATCCGGAAGTTCTTCCCAAAGAAAAAATGTTTTGTCTTCGATCTGCCCATT
CACCGCAGGAAGCTTGCCCAGCTTGAGAAACTACAAGATGAAGAGCTGGACCCTGAATTT
GTGCAACAAGTAGCAGACTTCTGTTCCTACATCTTTAGCAATTCCAAAACTAAAACTCTT
TCAGGAGGCATCAAGGTCAATGGGCCTCGTCTAGAGAGCCTAGTGCTGACCTATATCAAT
GCTATCAGCAGAGGGGATCTGCCCTGCATGGAGAACGCAGTCCTGGCCTTGGCCCAGATA
GAGAACTCAGCCGCAGTGCAAAAGGCTATTGCCCACTATGACCAGCAGATGGGCCAGAAG
GTGCAGCTGCCCGCAGAAACCCTCCAGGAGCTGCTGGACCTGCACAGGGTTAGTGAGAGG
GAGGCCACTGAAGTCTATATGAAGAACTCTTTCAAGGATGTGGACCATCTGTTTCAAAAG
AAATTAGCGGCCCAGCTAGACAAAAAGCGGGATGACTTTTGTAAACAGAATCAAGAAGCA
TCATCAGATCGTTGCTCAGCTTTACTTCAGGTCATTTTCAGTCCTCTAGAAGAAGAAGTG
AAGGCGGGAATTTATTCGAAACCAGGGGGCTATTGTCTCTTTATTCAGAAGCTACAAGAC
CTGGAGAAAAAGTACTATGAGGAACCAAGGAAGGGGATACAGGCTGAAGAGATTCTGCAG
ACATACTTGAAATCCAAGGAGTCTGTGACCGATGCAATTCTACAGACAGACCAGATTCTC
ACAGAAAAGGAAAAGGAGATTGAAGTGGAATGTGTAAAAGCTGAATCTGCACAGGCTTCA
GCAAAAATGGTGGAGGAAATGCAAATAAAGTATCAGCAGATGATGGAAGAGAAAGAGAAG
AGTTATCAAGAACATGTGAAACAATTGACTGAGAAGATGGAGAGGGAGAGGGCCCAGTTG
CTGGAAGAGCAAGAGAAGACCCTCACTAGTAAACTTCAGGAACAGGCCCGAGTACTAAAG
GAGAGATGCCAAGGTGAAAGTACCCAACTTCAAAATGAGATACAAAAGCTACAGAAGACC
CTGAAAAAAAAAACCAAGAGATATATGTCGCATAAGCTAAAGATCTAA

Protein Properties

Number of Residues

595

Molecular Weight

68113.6

Theoretical pI

6.46

Pfam Domain Function

GBP (PF02263 )
GBP_C (PF02841 )

Signals

["None"]

Transmembrane Regions

["27-47", "114-134"]

Protein Sequence

>Guanylate-binding protein 3
MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAG
KNKGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAV
LLSSTLVYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTL
RDFSLDLEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPI
HRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYIN
AISRGDLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSER
EATEVYMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEV
KAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQIL
TEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQL
LEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKKTKRYMSHKLKI

External Links

GenBank ID Protein

112382372

UniProtKB/Swiss-Prot ID

Q9H0R5

UniProtKB/Swiss-Prot Entry Name

GBP3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_018284.2

GeneCard ID