Identification |
HMDB Protein ID
| CDBP03626 |
Secondary Accession Numbers
| Not Available |
Name
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 |
Description
| Not Available |
Synonyms
|
- Gamma-9
|
Gene Name
| GNG8 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in signal transducer activity |
Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction |
GO Classification
|
Component |
cell part |
membrane part |
extrinsic to membrane |
extrinsic to plasma membrane |
heterotrimeric g-protein complex |
Function |
molecular transducer activity |
signal transducer activity |
Process |
signaling |
signaling pathway |
cell surface receptor linked signaling pathway |
g-protein coupled receptor protein signaling pathway |
|
Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 19q13.32 |
SNPs
| GNG8 |
Gene Sequence
|
>213 bp
ATGTCCAACAACATGGCCAAGATTGCCGAGGCCCGCAAGACGGTGGAACAGCTGAAGCTG
GAGGTGAACATCGACCGCATGAAGGTGTCGCAGGCAGCAGCGGAACTCCTGGCTTTCTGC
GAGACGCATGCCAAAGATGACCCGCTGGTGACGCCAGTACCCGCCGCGGAGAACCCCTTC
CGCGACAAGCGCCTCTTTTGTGTTCTGCTCTGA
|
Protein Properties |
Number of Residues
| 70 |
Molecular Weight
| 7841.1 |
Theoretical pI
| 7.27 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF
RDKRLFCVLL
|
External Links |
GenBank ID Protein
| 6164867 |
UniProtKB/Swiss-Prot ID
| Q9UK08 |
UniProtKB/Swiss-Prot Entry Name
| GBG8_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF188179 |
GeneCard ID
| GNG8 |
GenAtlas ID
| GNG8 |
HGNC ID
| HGNC:19664 |
References |
General References
| Not Available |