Identification
HMDB Protein ID CDBP03625
Secondary Accession Numbers Not Available
Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Description Not Available
Synonyms Not Available
Gene Name GNG7
Protein Type Receptor
Biological Properties
General Function Involved in signal transducer activity
Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum
GO Classification
Component
extrinsic to membrane
extrinsic to plasma membrane
heterotrimeric g-protein complex
cell part
membrane part
Function
molecular transducer activity
signal transducer activity
Process
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasmic side (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19p13.3
SNPs GNG7
Gene Sequence
>207 bp
ATGTCAGCCACTAACAACATAGCCCAGGCCCGGAAGCTGGTGGAACAGCTACGCATAGAA
GCCGGGATTGAGCGCATCAAGGTCTCCAAAGCGGCGTCTGACCTCATGAGCTACTGTGAG
CAACATGCTCGGAACGACCCCCTGCTGGTCGGAGTCCCTGCCTCGGAGAACCCCTTTAAG
GACAAGAAACCTTGTATTATTTTATAA
Protein Properties
Number of Residues 68
Molecular Weight 7521.7
Theoretical pI 8.77
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
MSATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFK
DKKPCIIL
GenBank ID Protein 3149954
UniProtKB/Swiss-Prot ID O60262
UniProtKB/Swiss-Prot Entry Name GBG7_HUMAN
PDB IDs Not Available
GenBank Gene ID AB010414
GeneCard ID GNG7
GenAtlas ID GNG7
HGNC ID HGNC:4410
References
General References Not Available