Identification
HMDB Protein ID CDBP03622
Secondary Accession Numbers Not Available
Name Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Description Not Available
Synonyms Not Available
Gene Name GNG3
Protein Type Receptor
Biological Properties
General Function Involved in signal transducer activity
Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction
GO Classification
Component
cell part
membrane part
extrinsic to membrane
extrinsic to plasma membrane
heterotrimeric g-protein complex
Function
molecular transducer activity
signal transducer activity
Process
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasmic side (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11p11
SNPs GNG3
Gene Sequence
>228 bp
ATGAAAGGTGAGACCCCGGTGAACAGCACTATGAGTATTGGGCAAGCACGCAAGATGGTG
GAACAGCTTAAGATTGAAGCCAGCTTGTGTCGGATAAAGGTGTCCAAGGCAGCAGCAGAC
CTGATGACTTACTGTGATGCCCACGCCTGTGAGGATCCCCTCATCACCCCTGTGCCCACT
TCGGAGAACCCCTTCCGGGAGAAGAAGTTCTTCTGTGCTCTCCTCTGA
Protein Properties
Number of Residues 75
Molecular Weight 8304.7
Theoretical pI 7.93
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT
SENPFREKKFFCALL
GenBank ID Protein 33150642
UniProtKB/Swiss-Prot ID P63215
UniProtKB/Swiss-Prot Entry Name GBG3_HUMAN
PDB IDs Not Available
GenBank Gene ID AF087900
GeneCard ID GNG3
GenAtlas ID GNG3
HGNC ID HGNC:4405
References
General References Not Available