| Identification |
|---|
| HMDB Protein ID
| CDBP03621 |
| Secondary Accession Numbers
| Not Available |
| Name
| Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| Description
| Not Available |
| Synonyms
|
- Transducin gamma chain
|
| Gene Name
| GNGT1 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in signal transducer activity |
| Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction |
| GO Classification
|
| Component |
| extrinsic to plasma membrane |
| heterotrimeric g-protein complex |
| cell part |
| membrane part |
| extrinsic to membrane |
| Function |
| molecular transducer activity |
| signal transducer activity |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q21.3 |
| SNPs
| GNGT1 |
| Gene Sequence
|
>225 bp
ATGCCAGTAATCAATATTGAGGACCTGACAGAAAAGGACAAATTGAAGATGGAAGTTGAC
CAGCTCAAGAAAGAAGTGACACTGGAAAGAATGCTAGTTTCCAAATGTTGTGAAGAAGTA
AGAGATTACGTTGAAGAACGATCTGGCGAGGATCCACTGGTAAAGGGCATCCCAGAGGAC
AAAAATCCCTTCAAGGAGCTCAAAGGAGGCTGTGTGATTTCATAA
|
| Protein Properties |
|---|
| Number of Residues
| 74 |
| Molecular Weight
| 8495.8 |
| Theoretical pI
| 4.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Guanine nucleotide-binding protein G(T) subunit gamma-T1
MPVINIEDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPED
KNPFKELKGGCVIS
|
| External Links |
|---|
| GenBank ID Protein
| 41393496 |
| UniProtKB/Swiss-Prot ID
| P63211 |
| UniProtKB/Swiss-Prot Entry Name
| GBG1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AC002076 |
| GeneCard ID
| GNGT1 |
| GenAtlas ID
| GNGT1 |
| HGNC ID
| HGNC:4411 |
| References |
|---|
| General References
| Not Available |