Identification |
HMDB Protein ID
| CDBP03612 |
Secondary Accession Numbers
| Not Available |
Name
| Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
Description
| Not Available |
Synonyms
|
- Transducin beta chain 1
|
Gene Name
| GNB1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTPase activity |
Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Corticotropin Activation of Cortisol Production | | Not Available | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | | Not Available | Vasopressin Regulation of Water Homeostasis | | Not Available | Excitatory Neural Signalling Through 5-HTR 4 and Serotonin | | Not Available | Intracellular Signalling Through Histamine H2 Receptor and Histamine | | Not Available |
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1p36.33 |
SNPs
| GNB1 |
Gene Sequence
|
>1023 bp
ATGAGTGAGCTTGACCAGTTACGGCAGGAGGCCGAGCAACTTAAGAACCAGATTCGAGAC
GCCAGGAAAGCATGTGCAGATGCAACTCTCTCTCAGATCACAAACAACATCGACCCAGTG
GGAAGAATCCAAATGCGCACGAGGAGGACACTGCGGGGGCACCTGGCCAAGATCTACGCC
ATGCACTGGGGCACAGACTCCAGGCTTCTCGTCAGTGCCTCGCAGGATGGTAAACTTATC
ATCTGGGACAGCTACACCACCAACAAGGTCCACGCCATCCCTCTGCGCTCCTCCTGGGTC
ATGACCTGTGCATATGCCCCTTCTGGGAACTATGTGGCCTGCGGTGGCCTGGATAACATT
TGCTCCATTTACAATCTGAAAACTCGTGAGGGGAACGTGCGCGTGAGTCGTGAGCTGGCA
GGACACACAGGTTACCTGTCCTGCTGCCGATTCCTGGATGACAATCAGATCGTCACCAGC
TCTGGAGACACCACGTGTGCCCTGTGGGACATCGAGACCGGCCAGCAGACGACCACGTTT
ACCGGACACACTGGAGATGTCATGAGCCTTTCTCTTGCTCCTGACACCAGACTGTTCGTC
TCTGGTGCTTGTGATGCTTCAGCCAAACTCTGGGATGTGCGAGAAGGCATGTGCCGGCAG
ACCTTCACTGGCCACGAGTCTGACATCAATGCCATATGCTTCTTTCCAAATGGCAATGCA
TTTGCCACTGGCTCAGACGACGCCACCTGCAGGCTGTTTGACCTTCGTGCTGACCAGGAG
CTCATGACTTACTCCCATGACAACATCATCTGCGGGATCACCTCTGTCTCCTTCTCCAAG
AGCGGGCGCCTCCTCCTTGCTGGGTACGACGACTTCAACTGCAACGTCTGGGATGCACTC
AAAGCCGACCGGGCAGGTGTCTTGGCTGGGCATGACAACCGCGTCAGCTGCCTGGGCGTG
ACTGACGATGGCATGGCTGTGGCGACAGGGTCCTGGGATAGCTTCCTCAAGATCTGGAAC
TAA
|
Protein Properties |
Number of Residues
| 340 |
Molecular Weight
| 37376.6 |
Theoretical pI
| 5.85 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF
TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
|
External Links |
GenBank ID Protein
| 31669 |
UniProtKB/Swiss-Prot ID
| P62873 |
UniProtKB/Swiss-Prot Entry Name
| GBB1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| X04526 |
GeneCard ID
| GNB1 |
GenAtlas ID
| GNB1 |
HGNC ID
| HGNC:4396 |
References |
General References
| Not Available |