Identification
HMDB Protein ID CDBP03598
Secondary Accession Numbers Not Available
Name Elongation factor Tu GTP-binding domain-containing protein 1
Description Not Available
Synonyms
  1. Protein FAM42A
Gene Name EFTUD1
Protein Type Enzyme
Biological Properties
General Function Involved in GTPase activity
Specific Function Not Available
GO Classification
Function
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 15q25.2
SNPs EFTUD1
Gene Sequence
>3363 bp
ATGGTGCTCAACAGTTTGGATAAGATGATTCAACTCCAGAAAAACACTGCCAACATCAGG
AATATTTGTGTTTTGGCTCATGTTGACCATGGAAAAACTACTCTGGCTGACTGTCTTATA
TCTAGCAATGGAATCATCTCCAGCCGCCTAGCAGGCAAGTTAAGGTACATGGACAGCAGA
GAAGATGAACAGATCCGAGGGATCACTATGAAATCCAGTGCCATTTCCCTACATTATGCA
ACAGGTAATGAGGAGTACCTGATCAATCTGATAGACTCTCCAGGACACGTGGACTTTTCC
TCAGAAGTATCAACCGCTGTTCGCATTTGTGATGGATGCATCATTGTGGTAGATGCTGTG
GAAGGAGTCTGTCCACAGACACAGGCAGTTCTGCGACAAGCTTGGCTTGAAAACATCCGT
CCGGTTTTAGTGATTAATAAGATTGATCGCTTGATAGTGGAACTGAAATTCACCCCACAA
GAGGCCTATTCTCACCTCAAGAATATTTTAGAACAGATTAATGCGCTCACAGGGACTCTT
TTTACTTCTAAAGTCCTAGAAGAAAGAGCAGAGAGGGAGACTGAATCCCAAGTGAATCCA
AATTCTGAACAAGGAGAGCAAGTATATGACTGGAGCACTGGCTTGGAGGACACAGATGAT
TCTCACCTTTACTTCTCTCCAGAACAGGGAAATGTGGTGTTTACCAGTGCAATAGATGGG
TGGGGCTTTGGAATTGAGCACTTCGCCAGAATCTACAGTCAAAAAATTGGCATCAAAAAG
GAAGTTCTTATGAAAACCTTGTGGGGAGATTACTATATAAATATGAAGGCTAAAAAGATC
ATGAAGGGTGATCAGGCCAAAGGAAAGAAACCTTTATTTGTACAGTTGATCCTGGAAAAT
ATATGGAGTTTGTATGATGCTGTTTTGAAAAAGGACAAAGACAAAATTGATAAAATAGTG
ACTTCTTTAGGATTAAAAATTGGAGCCCGGGAGGCACGACATTCAGACCCTAAAGTTCAG
ATCAACGCCATTTGCAGTCAGTGGCTACCCATATCCCATGCTGTTCTTGCTATGGTGTGT
CAGAAACTTCCTAGTCCCCTTGATATTACAGCTGAGAGAGTGGAGAGACTGATGTGCACA
GGATCACAAACTTTTGACTCTTTTCCACCAGAAACTCAAGCACTGAAAGCAGCTTTTATG
AAATGTGGAAGTGAGGACACTGCTCCAGTTATTATATTTGTTTCCAAAATGTTTGCAGTT
GATGCTAAGGCCTTGCCTCAGAATAAGCCAAGGCCTCTCACTCAAGAAGAAATTGCTCAG
AGACGTGAGCGTGCAAGACAAAGGCATGCAGAGAAGCTTGCAGCAGCACAGGGACAGGCA
CCCTTGGAGCCCACCCAAGATGGGAGTGCCATTGAAACATGTCCAAAAGGAGAGGAGCCA
AGAGGTGACGAGCAACAGGTGGAAAGTATGACCCCTAAACCTGTGCTCCAGGAAGAAAAC
AACCAAGAGTCTTTTATTGCATTTGCTCGGGTGTTCAGTGGTGTGGCTCGAAGAGGAAAG
AAAATTTTTGTCTTGGGGCCCAAATACAGTCCTCTTGAGTTTTTACGAAGGGTACCATTA
GGCTTCTCAGCTCCACCAGATGGCCTCCCCCAAGTCCCCCACATGGCATACTGTGCTCTG
GAAAACCTGTATCTTCTGATGGGAAGGGAACTGGAATATCTAGAGGAGGTACCTCCAGGA
AATGTGCTAGGAATAGGAGGCCTTCAAGATTTTGTGCTGAAATCTGCAACACTGTGTAGC
CTGCCATCCTGCCCACCATTTATACCACTCAACTTCGAAGCCACTCCTATTGTGAGAGTT
GCTGTTGAACCAAAACATCCAAGTGAAATGCCTCAGCTCGTAAAAGGAATGAAACTGTTA
AACCAGGCTGATCCCTGTGTCCAGATTTTAATTCAGGAAACGGGAGAGCACGTTTTAGTC
ACAGCAGGAGAAGTCCACCTTCAGCGATGCCTGGATGACTTAAAAGAAAGGTTTGCAAAG
ATTCATATCAGTGTATCTGAACCTATTATTCCATTCAGAGAAACAATCACAAAACCCCCA
AAAGTTGACATGGTCAATGAAGAAATAGGCAAACAGCAAAAAGTTGCAGTCATACACCAA
ATGAAAGAAGATCAAAGCAAAATCCCTGAAGGAATCCAAGTTGACTCTGACGGGCTAATC
ACCATAACAACTCCCAATAAACTTGCCACGCTCAGTGTTCGAGCCATGCCCCTTCCAGAA
GAAGTCACCCAGATTCTGGAAGAAAATAGTGATTTGATTCGTTCTATGGAGCAGTTGACA
TCCTCTTTGAATGAGGGTGAAAATACTCACATGATTCATCAGAAGACCCAAGAGAAAATT
TGGGAATTCAAAGGAAAACTGGAGCAACACCTAACAGGGAGAAGATGGAGGAACATTGTT
GACCAAATCTGGTCATTTGGCCCAAGAAAATGTGGGCCCAACATACTAGTCAATAAAAGT
GAAGATTTTCAGAACTCAGTATGGACAGGTCCAGCTGACAAAGCTTCAAAAGAAGCCAGT
AGATACCGAGATTTGGGCAATAGCATTGTGAGTGGCTTCCAACTAGCAACCCTCTCTGGC
CCCATGTGTGAGGAGCCTCTCATGGGTGTCTGTTTTGTTCTGGAAAAATGGGACCTAAGT
AAATTTGAGGAACAAGGAGCAAGTGATCTGGCAAAAGAGGGACAGGAGGAAAATGAAACC
TGTTCTGGTGGAAATGAAAACCAAGAGCTACAAGATGGCTGCTCTGAGGCCTTTGAGAAG
AGGACATCACAGAAAGGAGAATCTCCACTCACTGACTGCTATGGACCTTTCTCAGGACAG
CTAATTGCCACCATGAAAGAAGCATGTCGCTATGCACTGCAAGTGAAACCTCAGCGCCTG
ATGGCAGCTATGTACACATGTGACATCATGGCCACTGGTGATGTTCTCGGTCGAGTCTAT
GCTGTCTTGTCAAAGAGAGAAGGTCGGGTACTTCAAGAAGAAATGAAAGAAGGGACAGAC
ATGTTCATCATCAAGGCTGTGCTGCCTGTTGCTGAAAGCTTTGGTTTTGCTGATGAAATC
AGGAAGAGGACAAGTGGCCTGGCCAGCCCACAACTAGTATTCAGCCATTGGGAGATCATT
CCCAGTGACCCCTTCTGGGTGCCAACTACTGAGGAGGAATACTTGCACTTTGGGGAGAAG
GCTGACTCTGAGAACCAAGCCCGGAAGTACATGAACGCAGTACGAAAGCGGAAGGGGCTT
TATGTGGAAGAAAAGATTGTGGAGCATGCAGAAAAGCAGAGGACACTCAGCAAAAATAAG
TAG
Protein Properties
Number of Residues 1120
Molecular Weight 125428.7
Theoretical pI 5.72
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Elongation factor Tu GTP-binding domain-containing protein 1
MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSR
EDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAV
EGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTL
FTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDG
WGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGKKPLFVQLILEN
IWSLYDAVLKKDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVC
QKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAV
DAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAAQGQAPLEPTQDGSAIETCPKGEEP
RGDEQQVESMTPKPVLQEENNQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPL
GFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCS
LPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLV
TAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQ
MKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLT
SSLNEGENTHMIHQKTQEKIWEFKGKLEQHLTGRRWRNIVDQIWSFGPRKCGPNILVNKS
EDFQNSVWTGPADKASKEASRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLS
KFEEQGASDLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQ
LIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTD
MFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEK
ADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK
GenBank ID Protein 94966754
UniProtKB/Swiss-Prot ID Q7Z2Z2
UniProtKB/Swiss-Prot Entry Name ETUD1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_024580.5
GeneCard ID EFTUD1
GenAtlas ID EFTUD1
HGNC ID HGNC:25789
References
General References Not Available