Identification |
HMDB Protein ID
| CDBP03598 |
Secondary Accession Numbers
| Not Available |
Name
| Elongation factor Tu GTP-binding domain-containing protein 1 |
Description
| Not Available |
Synonyms
|
- Protein FAM42A
|
Gene Name
| EFTUD1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTPase activity |
Specific Function
| Not Available |
GO Classification
|
Function |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
pyrophosphatase activity |
purine nucleotide binding |
binding |
nucleotide binding |
catalytic activity |
hydrolase activity |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
gtpase activity |
nucleoside-triphosphatase activity |
hydrolase activity, acting on acid anhydrides |
|
Cellular Location
|
- Cytoplasmic
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 15q25.2 |
SNPs
| EFTUD1 |
Gene Sequence
|
>3363 bp
ATGGTGCTCAACAGTTTGGATAAGATGATTCAACTCCAGAAAAACACTGCCAACATCAGG
AATATTTGTGTTTTGGCTCATGTTGACCATGGAAAAACTACTCTGGCTGACTGTCTTATA
TCTAGCAATGGAATCATCTCCAGCCGCCTAGCAGGCAAGTTAAGGTACATGGACAGCAGA
GAAGATGAACAGATCCGAGGGATCACTATGAAATCCAGTGCCATTTCCCTACATTATGCA
ACAGGTAATGAGGAGTACCTGATCAATCTGATAGACTCTCCAGGACACGTGGACTTTTCC
TCAGAAGTATCAACCGCTGTTCGCATTTGTGATGGATGCATCATTGTGGTAGATGCTGTG
GAAGGAGTCTGTCCACAGACACAGGCAGTTCTGCGACAAGCTTGGCTTGAAAACATCCGT
CCGGTTTTAGTGATTAATAAGATTGATCGCTTGATAGTGGAACTGAAATTCACCCCACAA
GAGGCCTATTCTCACCTCAAGAATATTTTAGAACAGATTAATGCGCTCACAGGGACTCTT
TTTACTTCTAAAGTCCTAGAAGAAAGAGCAGAGAGGGAGACTGAATCCCAAGTGAATCCA
AATTCTGAACAAGGAGAGCAAGTATATGACTGGAGCACTGGCTTGGAGGACACAGATGAT
TCTCACCTTTACTTCTCTCCAGAACAGGGAAATGTGGTGTTTACCAGTGCAATAGATGGG
TGGGGCTTTGGAATTGAGCACTTCGCCAGAATCTACAGTCAAAAAATTGGCATCAAAAAG
GAAGTTCTTATGAAAACCTTGTGGGGAGATTACTATATAAATATGAAGGCTAAAAAGATC
ATGAAGGGTGATCAGGCCAAAGGAAAGAAACCTTTATTTGTACAGTTGATCCTGGAAAAT
ATATGGAGTTTGTATGATGCTGTTTTGAAAAAGGACAAAGACAAAATTGATAAAATAGTG
ACTTCTTTAGGATTAAAAATTGGAGCCCGGGAGGCACGACATTCAGACCCTAAAGTTCAG
ATCAACGCCATTTGCAGTCAGTGGCTACCCATATCCCATGCTGTTCTTGCTATGGTGTGT
CAGAAACTTCCTAGTCCCCTTGATATTACAGCTGAGAGAGTGGAGAGACTGATGTGCACA
GGATCACAAACTTTTGACTCTTTTCCACCAGAAACTCAAGCACTGAAAGCAGCTTTTATG
AAATGTGGAAGTGAGGACACTGCTCCAGTTATTATATTTGTTTCCAAAATGTTTGCAGTT
GATGCTAAGGCCTTGCCTCAGAATAAGCCAAGGCCTCTCACTCAAGAAGAAATTGCTCAG
AGACGTGAGCGTGCAAGACAAAGGCATGCAGAGAAGCTTGCAGCAGCACAGGGACAGGCA
CCCTTGGAGCCCACCCAAGATGGGAGTGCCATTGAAACATGTCCAAAAGGAGAGGAGCCA
AGAGGTGACGAGCAACAGGTGGAAAGTATGACCCCTAAACCTGTGCTCCAGGAAGAAAAC
AACCAAGAGTCTTTTATTGCATTTGCTCGGGTGTTCAGTGGTGTGGCTCGAAGAGGAAAG
AAAATTTTTGTCTTGGGGCCCAAATACAGTCCTCTTGAGTTTTTACGAAGGGTACCATTA
GGCTTCTCAGCTCCACCAGATGGCCTCCCCCAAGTCCCCCACATGGCATACTGTGCTCTG
GAAAACCTGTATCTTCTGATGGGAAGGGAACTGGAATATCTAGAGGAGGTACCTCCAGGA
AATGTGCTAGGAATAGGAGGCCTTCAAGATTTTGTGCTGAAATCTGCAACACTGTGTAGC
CTGCCATCCTGCCCACCATTTATACCACTCAACTTCGAAGCCACTCCTATTGTGAGAGTT
GCTGTTGAACCAAAACATCCAAGTGAAATGCCTCAGCTCGTAAAAGGAATGAAACTGTTA
AACCAGGCTGATCCCTGTGTCCAGATTTTAATTCAGGAAACGGGAGAGCACGTTTTAGTC
ACAGCAGGAGAAGTCCACCTTCAGCGATGCCTGGATGACTTAAAAGAAAGGTTTGCAAAG
ATTCATATCAGTGTATCTGAACCTATTATTCCATTCAGAGAAACAATCACAAAACCCCCA
AAAGTTGACATGGTCAATGAAGAAATAGGCAAACAGCAAAAAGTTGCAGTCATACACCAA
ATGAAAGAAGATCAAAGCAAAATCCCTGAAGGAATCCAAGTTGACTCTGACGGGCTAATC
ACCATAACAACTCCCAATAAACTTGCCACGCTCAGTGTTCGAGCCATGCCCCTTCCAGAA
GAAGTCACCCAGATTCTGGAAGAAAATAGTGATTTGATTCGTTCTATGGAGCAGTTGACA
TCCTCTTTGAATGAGGGTGAAAATACTCACATGATTCATCAGAAGACCCAAGAGAAAATT
TGGGAATTCAAAGGAAAACTGGAGCAACACCTAACAGGGAGAAGATGGAGGAACATTGTT
GACCAAATCTGGTCATTTGGCCCAAGAAAATGTGGGCCCAACATACTAGTCAATAAAAGT
GAAGATTTTCAGAACTCAGTATGGACAGGTCCAGCTGACAAAGCTTCAAAAGAAGCCAGT
AGATACCGAGATTTGGGCAATAGCATTGTGAGTGGCTTCCAACTAGCAACCCTCTCTGGC
CCCATGTGTGAGGAGCCTCTCATGGGTGTCTGTTTTGTTCTGGAAAAATGGGACCTAAGT
AAATTTGAGGAACAAGGAGCAAGTGATCTGGCAAAAGAGGGACAGGAGGAAAATGAAACC
TGTTCTGGTGGAAATGAAAACCAAGAGCTACAAGATGGCTGCTCTGAGGCCTTTGAGAAG
AGGACATCACAGAAAGGAGAATCTCCACTCACTGACTGCTATGGACCTTTCTCAGGACAG
CTAATTGCCACCATGAAAGAAGCATGTCGCTATGCACTGCAAGTGAAACCTCAGCGCCTG
ATGGCAGCTATGTACACATGTGACATCATGGCCACTGGTGATGTTCTCGGTCGAGTCTAT
GCTGTCTTGTCAAAGAGAGAAGGTCGGGTACTTCAAGAAGAAATGAAAGAAGGGACAGAC
ATGTTCATCATCAAGGCTGTGCTGCCTGTTGCTGAAAGCTTTGGTTTTGCTGATGAAATC
AGGAAGAGGACAAGTGGCCTGGCCAGCCCACAACTAGTATTCAGCCATTGGGAGATCATT
CCCAGTGACCCCTTCTGGGTGCCAACTACTGAGGAGGAATACTTGCACTTTGGGGAGAAG
GCTGACTCTGAGAACCAAGCCCGGAAGTACATGAACGCAGTACGAAAGCGGAAGGGGCTT
TATGTGGAAGAAAAGATTGTGGAGCATGCAGAAAAGCAGAGGACACTCAGCAAAAATAAG
TAG
|
Protein Properties |
Number of Residues
| 1120 |
Molecular Weight
| 125428.7 |
Theoretical pI
| 5.72 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Elongation factor Tu GTP-binding domain-containing protein 1
MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSR
EDEQIRGITMKSSAISLHYATGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAV
EGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTL
FTSKVLEERAERETESQVNPNSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDG
WGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKIMKGDQAKGKKPLFVQLILEN
IWSLYDAVLKKDKDKIDKIVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVC
QKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFMKCGSEDTAPVIIFVSKMFAV
DAKALPQNKPRPLTQEEIAQRRERARQRHAEKLAAAQGQAPLEPTQDGSAIETCPKGEEP
RGDEQQVESMTPKPVLQEENNQESFIAFARVFSGVARRGKKIFVLGPKYSPLEFLRRVPL
GFSAPPDGLPQVPHMAYCALENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCS
LPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLLNQADPCVQILIQETGEHVLV
TAGEVHLQRCLDDLKERFAKIHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQ
MKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPEEVTQILEENSDLIRSMEQLT
SSLNEGENTHMIHQKTQEKIWEFKGKLEQHLTGRRWRNIVDQIWSFGPRKCGPNILVNKS
EDFQNSVWTGPADKASKEASRYRDLGNSIVSGFQLATLSGPMCEEPLMGVCFVLEKWDLS
KFEEQGASDLAKEGQEENETCSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQ
LIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVYAVLSKREGRVLQEEMKEGTD
MFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEK
ADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK
|
External Links |
GenBank ID Protein
| 94966754 |
UniProtKB/Swiss-Prot ID
| Q7Z2Z2 |
UniProtKB/Swiss-Prot Entry Name
| ETUD1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_024580.5 |
GeneCard ID
| EFTUD1 |
GenAtlas ID
| EFTUD1 |
HGNC ID
| HGNC:25789 |
References |
General References
| Not Available |