Identification
HMDB Protein ID CDBP03589
Secondary Accession Numbers Not Available
Name Translation initiation factor eIF-2B subunit beta
Description Not Available
Synonyms
  1. S20I15
  2. S20III15
  3. eIF-2B GDP-GTP exchange factor subunit beta
Gene Name EIF2B2
Protein Type Enzyme
Biological Properties
General Function Involved in cellular metabolic process
Specific Function Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP
GO Classification
Process
metabolic process
cellular metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 14q24.3
SNPs EIF2B2
Gene Sequence
>1056 bp
ATGCCGGGATCCGCAGCGAAGGGCTCGGAGTTGTCAGAGAGGATCGAGAGCTTCGTGGAG
ACCCTGAAGCGGGGTGGTGGGCCGCGCAGCTCCGAGGAAATGGCTCGGGAGACCCTAGGG
TTGCTGCGCCAGATCATCACGGACCACCGCTGGAGCAACGCGGGGGAGCTGATGGAGCTG
ATCCGCAGAGAGGGCAGGAGGATGACGGCCGCTCAGCCCTCCGAGACCACCGTGGGCAAC
ATGGTGCGGAGAGTGCTCAAGATTATCCGGGAGGAGTATGGCAGACTCCATGGACGCAGC
GACGAGAGTGATCAGCAGGAGTCCCTGCACAAACTGTTGACATCCGGAGGCCTAAACGAG
GATTTCAGCTTCCATTATGCCCAACTCCAGTCCAACATCATTGAGGCGATTAATGAGCTG
CTAGTGGAGCTGGAAGGGACAATGGAGAACATTGCAGCCCAGGCTCTGGAGCACATTCAC
TCCAATGAGGTGATCATGACCATTGGCTTCTCCCGAACAGTAGAGGCCTTCCTCAAAGAG
GCTGCCCGAAAGAGGAAATTCCATGTCATTGTAGCAGAGTGTGCTCCTTTCTGCCAGGGT
CATGAAATGGCTGTGAATTTGTCCAAAGCAGGTATTGAGACAACTGTCATGACTGATGCT
GCCATTTTTGCCGTTATGTCAAGAGTCAACAAGGTGATCATTGGCACGAAGACCATCCTG
GCCAATGGGGCCCTGAGAGCTGTGACAGGAACTCACACTCTGGCACTGGCAGCAAAACAC
CATTCCACCCCACTCATCGTCTGTGCACCTATGTTCAAACTTTCTCCACAGTTCCCCAAT
GAAGAAGACTCATTTCATAAGTTTGTGGCTCCTGAAGAAGTCCTGCCATTCACAGAAGGG
GACATTCTGGAGAAGGTCAGCGTGCATTGCCCTGTGTTTGACTACGTTCCCCCAGAGCTC
ATTACCCTCTTTATCTCCAACATTGGTGGGAATGCACCTTCCTACATCTACCGCCTGATG
AGTGAACTCTACCATCCTGATGATCATGTTTTATGA
Protein Properties
Number of Residues 351
Molecular Weight 38989.3
Theoretical pI 6.12
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Translation initiation factor eIF-2B subunit beta
MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL
IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE
DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE
AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL
ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG
DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL
GenBank ID Protein 4809338
UniProtKB/Swiss-Prot ID P49770
UniProtKB/Swiss-Prot Entry Name EI2BB_HUMAN
PDB IDs Not Available
GenBank Gene ID AC006530
GeneCard ID EIF2B2
GenAtlas ID EIF2B2
HGNC ID HGNC:3258
References
General References Not Available