Identification |
HMDB Protein ID
| CDBP03585 |
Secondary Accession Numbers
| Not Available |
Name
| Elongation factor Ts, mitochondrial |
Description
| Not Available |
Synonyms
|
- EF-Ts
- EF-TsMt
|
Gene Name
| TSFM |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in translation elongation factor activity |
Specific Function
| Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome |
GO Classification
|
Component |
cell part |
intracellular |
Function |
binding |
nucleic acid binding |
translation factor activity, nucleic acid binding |
translation elongation factor activity |
rna binding |
Process |
translational elongation |
macromolecule biosynthetic process |
cellular macromolecule biosynthetic process |
metabolic process |
biosynthetic process |
|
Cellular Location
|
- Mitochondrion
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12q14.1 |
SNPs
| TSFM |
Gene Sequence
|
>978 bp
ATGTCGCTGCTGCGGTCGCTGCGCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGCT
GGGTCTCTTCTGCGTCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCCGTCTG
TCTGCCTCGGCCTCCAGCAAGGAGCTCCTCATGAAGCTGCGGCGGAAAACAGGCTACTCC
TTTGTAAATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAACAGGCAGAGATC
TGGCTCCACAAGGAGGCCCAGAAGGAGGGCTGGAGCAAAGCTGCCAAGCTCCAAGGGAGG
AAGACCAAAGAAGGCCTGATTGGGCTGTTGCAGGAAGGAAACACAACTGTATTAGTAGAG
GTAAACTGTGAGACAGATTTTGTTTCTAGAAATTTAAAATTTCAACTGTTGGTCCAGCAA
GTAGCCCTTGGAACCATGATGCATTGTCAGACCCTAAAGGATCAACCCTCTGCATACAGT
AAAGGTTTCTTGAATTCCTCTGAGCTTTCTGGACTTCCAGCTGGGCCTGACAGAGAAGGC
TCACTCAAGGATCAGTTGGCTTTAGCAATTGGAAAACTGGGAGAAAACATGATTCTTAAA
CGAGCTGCATGGGTGAAGGTGCCATCTGGGTTCTACGTTGGCTCTTATGTCCACGGAGCA
ATGCAGAGTCCCTCACTTCACAAGCTGGTGCTGGGGAAGTATGGGGCCCTGGTCATCTGT
GAGACGTCTGAACAGAAAACAAACCTTGAAGACGTTGGCCGCCGCCTTGGGCAGCATGTG
GTGGGCATGGCCCCCCTCTCTGTTGGCTCCCTGGACGATGAGCCTGGGGGAGAGGCAGAG
ACTAAGATGCTGTCCCAGCCGTATTTGCTGGATCCCTCCATTACCTTGGGGCAGTATGTG
CAGCCTCAGGGGGTGTCGGTAGTAGACTTTGTGCGGTTTGAATGTGGAGAAGGTGAAGAG
GCAGCAGAAACTGAATAG
|
Protein Properties |
Number of Residues
| 325 |
Molecular Weight
| 35390.4 |
Theoretical pI
| 8.56 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Elongation factor Ts, mitochondrial
MSLLRSLRVFLVARTGSYPAGSLLRQSPQPRHTFYAGPRLSASASSKELLMKLRRKTGYS
FVNCKKALETCGGDLKQAEIWLHKEAQKEGWSKAAKLQGRKTKEGLIGLLQEGNTTVLVE
VNCETDFVSRNLKFQLLVQQVALGTMMHCQTLKDQPSAYSKGFLNSSELSGLPAGPDREG
SLKDQLALAIGKLGENMILKRAAWVKVPSGFYVGSYVHGAMQSPSLHKLVLGKYGALVIC
ETSEQKTNLEDVGRRLGQHVVGMAPLSVGSLDDEPGGEAETKMLSQPYLLDPSITLGQYV
QPQGVSVVDFVRFECGEGEEAAETE
|
External Links |
GenBank ID Protein
| 4416086 |
UniProtKB/Swiss-Prot ID
| P43897 |
UniProtKB/Swiss-Prot Entry Name
| EFTS_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF110399 |
GeneCard ID
| TSFM |
GenAtlas ID
| TSFM |
HGNC ID
| HGNC:12367 |
References |
General References
| Not Available |