Cannabis Compound Database: Showing Protein Dynamin-3 (CDBP03579)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP03579

Secondary Accession Numbers

Not Available

Name

Dynamin-3

Description

Not Available

Synonyms

Dynamin, testicular
T-dynamin

Gene Name

DNM3

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).

GO Classification

Biological Process
synapse assembly
endocytosis
filopodium assembly
Cellular Component
mitochondrion
perinuclear region of cytoplasm
postsynaptic density
microtubule
Function
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
Molecular Function
GTPase activity
phospholipid binding
GTP binding

Cellular Location

Cytoplasm
Cytoplasm (Potential)
cytoskeleton (Potential)

Pathways

Name	SMPDB/Pathwhiz	KEGG
Endocytosis	Not Available
Fc gamma R-mediated phagocytosis	Not Available
Synaptic vesicle cycle	Not Available
Endocrine and other factor-regulated calcium reabsorption	Not Available
Bacterial invasion of epithelial cells	Not Available

Gene Properties

Chromosome Location

Locus

1q24.3

SNPs

DNM3

Gene Sequence

>2580 bp
ATGGGGAACCGGGAGATGGAGGAGCTGATCCCGCTGGTGAACCGTCTGCAGGACGCGTTT
TCGGCGCTGGGACAGAGCTGCCTGCTGGAGCTGCCGCAGATCGCCGTGGTGGGCGGCCAG
AGCGCCGGCAAGAGCTCGGTGCTCGAGAACTTCGTGGGCAGGGACTTTCTCCCTCGAGGG
TCGGGCATTGTAACAAGACGACCTCTTGTGCTGCAGCTTGTTACTTCTAAAGCAGAATAT
GCCGAGTTTCTACATTGCAAAGGAAAGAAATTTACAGATTTTGATGAAGTTCGCCTTGAG
ATTGAAGCAGAAACAGATCGCGTGACTGGAATGAATAAAGGCATTTCCTCCATACCCATT
AATTTACGAGTCTATTCCCCACACGTGTTAAATCTAACCCTTATTGATCTACCTGGAATA
ACTAAAGTGCCTGTGGGAGATCAGCCACCAGATATCGAGTATCAGATCAGAGAAATGATT
ATGCAGTTCATCACGAGGGAGAACTGTCTGATTTTAGCTGTTACTCCAGCCAACACTGAT
CTTGCAAACTCAGATGCGCTGAAGCTAGCTAAAGAAGTTGATCCTCAAGGTCTGAGAACC
ATTGGAGTTATCACCAAACTGGACCTTATGGATGAAGGAACGGATGCCAGGGATGTTCTA
GAGAACAAACTGTTGCCTCTTCGCAGGGGTTACGTGGGGGTGGTAAACAGAAGCCAGAAG
GACATAGATGGGAAGAAGGACATAAAGGCAGCCATGCTGGCAGAGAGGAAGTTTTTCCTT
TCCCACCCGGCTTACAGACATATCGCTGACCGAATGGGAACCCCACACCTGCAGAAGGTC
CTTAATCAGCAACTTACCAACCACATTCGGGATACCCTACCAAACTTCAGGAACAAACTA
CAGGGACAGTTGCTCTCCATAGAACATGAAGTAGAAGCCTACAAAAATTTCAAACCAGAA
GACCCAACAAGGAAGACCAAAGCATTGCTGCAGATGGTTCAGCAATTTGCTGTGGACTTT
GAGAAGAGAATTGAAGGGTCAGGGGATCAAGTAGATACCCTGGAACTCTCAGGTGGTGCT
AAAATCAATCGTATTTTTCATGAACGCTTTCCTTTTGAGATAGTAAAGATGGAGTTCAAT
GAGAAAGAATTGCGAAGAGAAATAAGCTATGCAATCAAAAACATACATGGTATCAGGACA
GGGTTGTTTACTCCAGACATGGCATTTGAAGCGATAGTCAAGAAACAGATTGTAAAGTTG
AAAGGGCCTTCCTTGAAGAGTGTGGATCTGGTAATACAAGAATTAATCAACACTGTGAAG
AAGTGTACCAAAAAACTGGCAAACTTCCCCAGACTCTGCGAGGAAACGGAAAGGATTGTT
GCTAACCACATTCGTGAGCGAGAAGGGAAGACAAAGGACCAGGTATTGCTATTGATTGAC
ATTCAAGTCTCTTACATCAACACCAACCATGAAGACTTCATTGGCTTCGCAAATGCTCAG
CAGAGGAGCAGTCAGGTTCACAAGAAAACCACAGTTGGAAATCAGGTGATTCGCAAGGGG
TGGCTCACCATCAGCAACATTGGCATCATGAAAGGCGGCTCGAAGGGATACTGGTTCGTC
CTTACTGCGGAAAGCTTGTCCTGGTATAAAGATGATGAGGAAAAAGAAAAGAAGTACATG
CTTCCCTTGGACAACCTGAAAGTTCGGGATGTGGAAAAGAGCTTTATGTCTAGCAAGCAC
ATCTTTGCACTCTTTAATACAGAGCAAAGGAATGTATACAAAGACTATCGCTTCCTTGAG
CTGGCATGTGATTCCCAGGAGGATGTCGACAGCTGGAAGGCATCTCTACTAAGAGCTGGG
GTCTATCCTGACAAATCTGTAGCTGAAAATGATGAGAATGGACAAGCAGAAAACTTTTCC
ATGGACCCACAATTGGAGAGGCAAGTGGAGACCATTCGCAACCTCGTAGACTCCTACATG
TCCATTATCAACAAATGTATCCGAGATCTAATTCCAAAAACAATAATGCACCTTATGATC
AATAACGTTAAAGATTTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCTTCAGAGGAC
CAAAATACCCTGATGGAGGAATCTGCTGAGCAGGCTCAGCGCCGGGATGAGATGCTTCGA
ATGTATCAAGCACTGAAAGAAGCCCTTGGGATAATTGGGGACATCAGCACAGCCACCGTG
TCCACTCCGGCACCCCCTCCAGTGGATGACTCCTGGATACAGCACTCTCGCAGGTCACCT
CCTCCAAGCCCCACAACCCAAAGGAGGCCAACACTAAGTGCTCCCCTCGCAAGGCCCACA
TCCGGCCGAGGACCAGCTCCTGCCATTCCCTCTCCTGGCCCCCACTCTGGGGCTCCTCCA
GTCCCATTCCGTCCAGGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCCTTCGGAGCC
CCTCCACAAGTTCCATCTAGGCCTACGAGGGCCCCGCCCAGTGTCCCAAGCCGGAGACCA
CCCCCATCACCAACTCGTCCCACTATAATCCGCCCACTAGAATCCTCCCTGTTAGACTAA

Protein Properties

Number of Residues

869

Molecular Weight

96681.0

Theoretical pI

8.228

Pfam Domain Function

PH (PF00169 )
Dynamin_N (PF00350 )
Dynamin_M (PF01031 )
GED (PF02212 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Dynamin-3
MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPI
NLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTD
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQK
DIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL
QGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGA
KINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKL
KGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLID
IQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQGTNLPPSRQIVIRKGWLTISNIGIM
KGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQR
NVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVE
TIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAE
QAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRP
TLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTR
APPSVPSRRPPPSPTRPTIIRPLESSLLD

External Links

GenBank ID Protein

209915561

UniProtKB/Swiss-Prot ID

Q9UQ16

UniProtKB/Swiss-Prot Entry Name

DYN3_HUMAN

PDB IDs