Identification |
HMDB Protein ID
| CDBP03561 |
Secondary Accession Numbers
| Not Available |
Name
| GTP-binding protein Di-Ras1 |
Description
| Not Available |
Synonyms
|
- Distinct subgroup of the Ras family member 1
- Ras-related inhibitor of cell growth
- Rig
- Small GTP-binding tumor suppressor 1
|
Gene Name
| DIRAS1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| Displays low GTPase activity and exist predominantly in the GTP-bound form |
GO Classification
|
Component |
cell part |
intracellular |
membrane |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
catalytic activity |
hydrolase activity |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
gtpase activity |
nucleoside-triphosphatase activity |
hydrolase activity, acting on acid anhydrides |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
pyrophosphatase activity |
Process |
regulation of biological process |
regulation of cellular process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
biological regulation |
|
Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasmic side (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 19p13.3 |
SNPs
| DIRAS1 |
Gene Sequence
|
>597 bp
ATGCCGGAACAGAGTAACGATTACCGCGTGGTGGTGTTCGGGGCGGGCGGCGTGGGCAAG
AGCTCGCTGGTGCTGCGCTTCGTGAAGGGCACGTTCCGCGACACCTACATCCCCACCATC
GAGGACACCTACCGGCAGGTGATCAGCTGCGACAAGAGCGTGTGCACGCTGCAGATCACA
GACACCACCGGCAGCCACCAGTTCCCGGCCATGCAGCGCCTGTCCATCTCCAAGGGCCAC
GCCTTCATCCTGGTGTTCTCCGTCACCAGCAAGCAGTCGCTGGAGGAGCTGGGGCCCATC
TACAAGCTCATCGTGCAGATCAAGGGCAGCGTGGAGGACATCCCCGTGATGCTCGTGGGC
AACAAGTGCGATGAGACGCAGCGGGAGGTGGACACGCGCGAGGCGCAGGCGGTGGCCCAG
GAGTGGAAGTGCGCTTTCATGGAGACCTCGGCCAAGATGAACTACAACGTCAAGGAGCTC
TTCCAGGAGCTGCTGACGCTGGAGACGCGCCGGAACATGAGCCTCAACATCGACGGCAAG
CGCTCCGGGAAGCAGAAGAGGACAGACCGCGTCAAGGGCAAATGCACCCTCATGTGA
|
Protein Properties |
Number of Residues
| 198 |
Molecular Weight
| 22328.6 |
Theoretical pI
| 8.97 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>GTP-binding protein Di-Ras1
MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQIT
DTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVG
NKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGK
RSGKQKRTDRVKGKCTLM
|
External Links |
GenBank ID Protein
| 21624248 |
UniProtKB/Swiss-Prot ID
| O95057 |
UniProtKB/Swiss-Prot Entry Name
| DIRA1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB076888 |
GeneCard ID
| DIRAS1 |
GenAtlas ID
| DIRAS1 |
HGNC ID
| HGNC:19127 |
References |
General References
| Not Available |