Identification
HMDB Protein ID CDBP03561
Secondary Accession Numbers Not Available
Name GTP-binding protein Di-Ras1
Description Not Available
Synonyms
  1. Distinct subgroup of the Ras family member 1
  2. Ras-related inhibitor of cell growth
  3. Rig
  4. Small GTP-binding tumor suppressor 1
Gene Name DIRAS1
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Displays low GTPase activity and exist predominantly in the GTP-bound form
GO Classification
Component
cell part
intracellular
membrane
Function
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
Process
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
biological regulation
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasmic side (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19p13.3
SNPs DIRAS1
Gene Sequence
>597 bp
ATGCCGGAACAGAGTAACGATTACCGCGTGGTGGTGTTCGGGGCGGGCGGCGTGGGCAAG
AGCTCGCTGGTGCTGCGCTTCGTGAAGGGCACGTTCCGCGACACCTACATCCCCACCATC
GAGGACACCTACCGGCAGGTGATCAGCTGCGACAAGAGCGTGTGCACGCTGCAGATCACA
GACACCACCGGCAGCCACCAGTTCCCGGCCATGCAGCGCCTGTCCATCTCCAAGGGCCAC
GCCTTCATCCTGGTGTTCTCCGTCACCAGCAAGCAGTCGCTGGAGGAGCTGGGGCCCATC
TACAAGCTCATCGTGCAGATCAAGGGCAGCGTGGAGGACATCCCCGTGATGCTCGTGGGC
AACAAGTGCGATGAGACGCAGCGGGAGGTGGACACGCGCGAGGCGCAGGCGGTGGCCCAG
GAGTGGAAGTGCGCTTTCATGGAGACCTCGGCCAAGATGAACTACAACGTCAAGGAGCTC
TTCCAGGAGCTGCTGACGCTGGAGACGCGCCGGAACATGAGCCTCAACATCGACGGCAAG
CGCTCCGGGAAGCAGAAGAGGACAGACCGCGTCAAGGGCAAATGCACCCTCATGTGA
Protein Properties
Number of Residues 198
Molecular Weight 22328.6
Theoretical pI 8.97
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>GTP-binding protein Di-Ras1
MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQIT
DTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVG
NKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGK
RSGKQKRTDRVKGKCTLM
GenBank ID Protein 21624248
UniProtKB/Swiss-Prot ID O95057
UniProtKB/Swiss-Prot Entry Name DIRA1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB076888
GeneCard ID DIRAS1
GenAtlas ID DIRAS1
HGNC ID HGNC:19127
References
General References Not Available