| Identification |
|---|
| HMDB Protein ID
| CDBP03540 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cell cycle progression protein 1 |
| Description
| Not Available |
| Synonyms
|
- Cell cycle progression restoration protein 8
|
| Gene Name
| CCPG1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Replication, recombination and repair |
| Specific Function
| Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. May be involved in cell cycle regulation |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Single-pass type II membrane protein
- Cytoplasmic granule membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 15q21.1 |
| SNPs
| CCPG1 |
| Gene Sequence
|
>2274 bp
ATGTCTGAAAATTCCAGTGACAGTGATTCATCTTGTGGTTGGACTGTCATCAGTCATGAG
GGGTCAGATATAGAAATGTTGAATTCTGTGACCCCCACTGACAGCTGTGAGCCCGCCCCA
GAATGTTCATCTTTAGAGCAAGAGGAGCTTCAAGCATTGCAGATAGAGCAAGGAGAAAGC
AGCCAAAATGGCACAGTGCTTATGGAAGAAACTGCTTATCCAGCTTTGGAGGAAACCAGC
TCAACAATTGAGGCAGAGGAACAAAAGATACCCGAAGACAGTATCTATATTGGAACTGCC
AGTGATGATTCTGATATTGTTACCCTTGAGCCACCTAAGTTAGAAGAAATTGGAAATCAA
GAAGTTGTCATTGTTGAAGAAGCACAGAGTTCAGAAGACTTTAACATGGGCTCTTCCTCT
AGCAGCCAGTATACTTTCTGTCAGCCAGAAACTGTATTTTCATCTCAGCCTAGTGACGAT
GAATCAAGTAGTGATGAAACCAGTAATCAGCCCAGTCCTGCCTTTAGACGACGCCGTGCT
AGGAAGAAGACCGTTTCTGCTTCAGAATCTGAAGACCGGCTAGTTGCTGAACAAGAAACT
GAACCTTCTAAGGAGTTGAGTAAACGTCAGTTCAGTAGTGGTCTCAATAAGTGTGTTATA
CTTGCTTTGGTGATTGCAATCAGCATGGGATTTGGCCATTTCTATGGCACAATTCAGATT
CAGAAGCGTCAACAGTTAGTCAGAAAGATACATGAAGATGAATTGAATGATATGAAGGAT
TATCTTTCCCAGTGTCAACAGGAACAAGAATCTTTTATAGATTATAAGTCATTGAAAGAA
AATCTTGCAAGGTGTTGGACACTTACTGAAGCAGAGAAGATGTCCTTTGAAACTCAGAAA
ACGAACCTTGCTACAGAAAATCAGTATTTAAGAGTATCCTTGGAGAAGGAAGAAAAAGCC
TTATCCTCATTACAGGAAGAGTTAAACAAACTAAGAGAACAGATTAGAATATTGGAAGAT
AAAGGGACAAGTACTGAATTAGTTAAAGAAAATCAGAAACTTAAGCAGCATTTGGAAGAG
GAAAAGCAGAAAAAACACAGCTTTCTTAGTCAAAGGGAGACTCTGTTGACAGAAGCAAAG
ATGCTAAAGAGAGAACTGGAGAGAGAACGACTAGTAACTACGGCTTTAAGGGGGGAACTC
CAGCAGTTAAGTGGTAGTCAGTTACATGGCAAGTCAGATTCTCCCAATGTATATACTGAA
AAAAAGGAAATAGCAATCTTACGGGAAAGACTCACTGAGCTGGAACGGAAGCTAACCTTC
GAACAGCAGCGTTCTGATTTGTGGGAAAGATTGTATGTTGAGGCAAAAGATCAAAATGGA
AAACAAGGAACAGATGGAAAAAAGAAAGGGGGCAGAGGAAGCCACAGGGCTAAAAATAAG
TCAAAGGAAACATTTTTGGGTTCAGTTAAGGAAACATTTGATGCCATGAAGAATTCTACC
AAGGAGTTTGTAAGGCATCATAAAGAGAAAATTAAGCAGGCTAAAGAAGCTGTGAAGGAA
AATCTGAAAAAATTCTCAGATTCAGTTAAATCCACTTTCAGACACTTTAAAGATACCACC
AAGAATATCTTTGATGAAAAGGGTAATAAAAGATTTGGTGCTACAAAAGAAGCAGCTGAA
AAACCAAGAACAGTTTTTAGTGACTATTTACATCCACAGTATAAGGCACCTACAGAAAAC
CATCATAATAGAGGCCCTACTATGCAAAATGATGGAAGGAAAGAAAAGCCAGTTCACTTT
AAAGAATTCAGAAAAAATACAAATTCAAAGAAATGCAGTCCTGGGCATGATTGTAGAGAA
AATTCTCATTCTTTCAGAAAGGCTTGTTCTGGTGTATTTGATTGTGCTCAACAAGAGTCC
ATGAGCCTTTTTAACACAGTGGTGAATCCTATAAGGATGGATGAATTTAGACAGATAATT
CAAAGGTACATGTTAAAAGAACTGGATACTTTTTGTCACTGGAACGAACTTGATCAGTTC
ATCAATAAGTTTTTCCTAAACGGTGTCTTTATACATGATCAGAAGCTCTTCACTGACTTT
GTTAATGATGTTAAAGATTATCTTAGAAACATGAAGGAATATGAAGTAGATAATGATGGA
GTATTTGAGAAGTTGGATGAATATATATATAGACACTTCTTTGGTCACACTTTTTCCCCT
CCATATGGACCCAGGTCGGTTTACATAAAACCGTGTCATTACAGTAGTTTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 757 |
| Molecular Weight
| 87339.7 |
| Theoretical pI
| 5.78 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cell cycle progression protein 1
MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGES
SQNGTVLMEETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQ
EVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRA
RKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQI
QKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWTLTEAEKMSFETQK
TNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEE
EKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTE
KKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNK
SKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTT
KNIFDEKGNKRFGATKEAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHF
KEFRKNTNSKKCSPGHDCRENSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQII
QRYMLKELDTFCHWNELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDG
VFEKLDEYIYRHFFGHTFSPPYGPRSVYIKPCHYSSL
|
| External Links |
|---|
| GenBank ID Protein
| 75677585 |
| UniProtKB/Swiss-Prot ID
| Q9ULG6 |
| UniProtKB/Swiss-Prot Entry Name
| CCPG1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_004748.3 |
| GeneCard ID
| CCPG1 |
| GenAtlas ID
| CCPG1 |
| HGNC ID
| HGNC:24227 |
| References |
|---|
| General References
| Not Available |