| Identification |
|---|
| HMDB Protein ID
| CDBP03538 |
| Secondary Accession Numbers
| Not Available |
| Name
| CDC42 small effector protein 1 |
| Description
| Not Available |
| Synonyms
|
- CDC42-binding protein SCIP1
- Small effector of CDC42 protein 1
|
| Gene Name
| CDC42SE1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTPase inhibitor activity |
| Specific Function
| Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Cytoplasm
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21.3 |
| SNPs
| CDC42SE1 |
| Gene Sequence
|
>240 bp
ATGAGTGAATTTTGGCACAAACTGGGCTGCTGTGTGGTAGAGAAACCCCAGCCGAAGAAG
AAGAGAAGACGGATTGACCGGACCATGATTGGGGAACCAATGAATTTTGTTCACCTGACT
CACATTGGCTCAGGGGAGATGGGGGCCGGAGATGGACTTGCCATGACAGGTGCAGTTCAG
GAGCAGATGAGATCCAAGGGAAACCGAGATAGGCCATGGAGCAATTCTAGGGGCTTATAG
|
| Protein Properties |
|---|
| Number of Residues
| 79 |
| Molecular Weight
| 8925.3 |
| Theoretical pI
| 10.76 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>CDC42 small effector protein 1
MSEFWHKLGCCVVEKPQPKKKRRRIDRTMIGEPMNFVHLTHIGSGEMGAGDGLAMTGAVQ
EQMRSKGNRDRPWSNSRGL
|
| External Links |
|---|
| GenBank ID Protein
| 9453924 |
| UniProtKB/Swiss-Prot ID
| Q9NRR8 |
| UniProtKB/Swiss-Prot Entry Name
| C42S1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF187845 |
| GeneCard ID
| CDC42SE1 |
| GenAtlas ID
| CDC42SE1 |
| HGNC ID
| HGNC:17719 |
| References |
|---|
| General References
| Not Available |