| Identification |
|---|
| HMDB Protein ID
| CDBP03536 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cdc42 effector protein 4 |
| Description
| Not Available |
| Synonyms
|
- Binder of Rho GTPases 4
|
| Gene Name
| CDC42EP4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP-Rho binding |
| Specific Function
| Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Endomembrane system
- Peripheral membrane protein
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q24-q25 |
| SNPs
| CDC42EP4 |
| Gene Sequence
|
>1071 bp
ATGCCAATCCTCAAGCAACTGGTGTCCAGCTCGGTGCACTCCAAGCGCCGTTCCCGAGCG
GACCTCACGGCCGAGATGATCAGCGCCCCGCTGGGCGACTTCCGCCACACCATGCACGTT
GGCCGGGCCGGAGACGCCTTTGGGGACACCTCCTTCCTCAATAGCAAGGCTGGCGAGCCC
GACGGCGAGTCCTTGGACGAACAGCCCTCTTCTTCATCTTCCAAACGCAGTCTCCTGTCC
AGGAAGTTCCGGGGCAGCAAGCGGTCACAGTCGGTGACCAGGGGGGAGCGGGAGCAGCGT
GACATGCTGGGCTCCCTGCGGGACTCGGCCCTGTTTGTCAAGAATGCCATGTCCCTGCCC
CAGCTCAATGAGAAGGAGGCCGCGGAGAAGGGCACCAGTAAGCTGCCCAAGAGCCTGTCA
TCCAGCCCCGTGAAGAAGGCCAATGACGGGGAGGGCGGCGATGAGGAGGCGGGCACGGAG
GAGGCAGTGCCCCGTCGGAATGGGGCCGCGGGTCCACATTCCCCTGACCCCCTCCTCGAT
GAGCAGGCCTTTGGGGATCTGACAGATCTGCCTGTCGTGCCCAAGGCCACGTACGGGCTG
AAGCATGCGGAGTCCATCATGTCCTTCCACATCGACCTGGGGCCCTCCATGCTGGGTGAC
GTCCTCAGCATCATGGACAAGGAGGAGTGGGACCCCGAGGAGGGGGAGGGTGGTTACCAT
GGCGATGAGGGCGCCGCTGGCACCATCACCCAGGCTCCCCCGTACGCCGTGGCGGCCCCT
CCCCTGGCAAGGCAGGAAGGCAAGGCTGGCCCAGACTTGCCCTCCCTCCCCTCCCATGCT
CTGGAGGATGAGGGGTGGGCAGCAGCGGCCCCCAGCCCCGGCTCAGCCCGCAGCATGGGC
AGCCACACCACACGGGACAGCAGCTCCCTCTCCAGCTGCACCTCAGGCATCCTGGAGGAG
CGCAGCCCTGCCTTCCGGGGGCCGGACAGGGCCCGGGCTGCTGTCTCAAGACAGCCAGAC
AAGGAGTTCTCCTTCATGGATGAGGAGGAGGAGGATGAAATCCGTGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 356 |
| Molecular Weight
| 37979.4 |
| Theoretical pI
| 4.82 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cdc42 effector protein 4
MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP
DGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLP
QLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLD
EQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYH
GDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPSHALEDEGWAAAAPSPGSARSMG
SHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV
|
| External Links |
|---|
| GenBank ID Protein
| 11036449 |
| UniProtKB/Swiss-Prot ID
| Q9H3Q1 |
| UniProtKB/Swiss-Prot Entry Name
| BORG4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB042237 |
| GeneCard ID
| CDC42EP4 |
| GenAtlas ID
| CDC42EP4 |
| HGNC ID
| HGNC:17147 |
| References |
|---|
| General References
| Not Available |