Identification |
HMDB Protein ID
| CDBP03517 |
Secondary Accession Numbers
| Not Available |
Name
| ADP-ribosylation factor 5 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| ARF5 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus |
GO Classification
|
Component |
cell part |
intracellular |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
Process |
biological regulation |
regulation of biological process |
regulation of cellular process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
|
Cellular Location
|
- Cytoplasm
- perinuclear region
- Golgi apparatus
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:7 |
Locus
| 7q31.3 |
SNPs
| ARF5 |
Gene Sequence
|
>543 bp
ATGGGCCTCACCGTGTCCGCGCTCTTTTCGCGGATCTTCGGGAAGAAGCAGATGCGGATT
CTCATGGTTGGCTTGGATGCGGCTGGCAAGACCACAATCCTGTACAAACTGAAGTTGGGG
GAGATTGTCACCACCATCCCAACCATAGGCTTCAATGTAGAAACAGTGGAATATAAGAAC
ATCTGTTTCACAGTCTGGGACGTGGGAGGCCAGGACAAGATTCGGCCTCTGTGGCGGCAC
TACTTCCAGAACACTCAGGGCCTCATCTTTGTGGTGGACAGTAATGACCGGGAGCGGGTC
CAAGAATCTGCTGATGAACTCCAGAAGATGCTGCAGGAGGACGAGCTGCGGGATGCAGTG
CTGCTGGTATTTGCCAACAAGCAGGACATGCCCAACGCCATGCCCGTGAGCGAGCTGACT
GACAAGCTGGGGCTACAGCACTTACGCAGCCGCACGTGGTATGTCCAGGCCACCTGTGCC
ACCCAAGGCACAGGTCTGTACGATGGTCTGGACTGGCTGTCCCACGAGCTGTCAAAGCGC
TAA
|
Protein Properties |
Number of Residues
| 180 |
Molecular Weight
| 20529.5 |
Theoretical pI
| 6.79 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>ADP-ribosylation factor 5
MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV
LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
|
External Links |
GenBank ID Protein
| 20147661 |
UniProtKB/Swiss-Prot ID
| P84085 |
UniProtKB/Swiss-Prot Entry Name
| ARF5_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF493884 |
GeneCard ID
| ARF5 |
GenAtlas ID
| ARF5 |
HGNC ID
| HGNC:658 |
References |
General References
| Not Available |