| Identification |
|---|
| HMDB Protein ID
| CDBP03515 |
| Secondary Accession Numbers
| Not Available |
| Name
| ADP-ribosylation factor 3 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| ARF3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| guanyl ribonucleotide binding |
| gtp binding |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
| small gtpase mediated signal transduction |
|
| Cellular Location
|
- Cytoplasm
- perinuclear region
- Golgi apparatus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12q13 |
| SNPs
| ARF3 |
| Gene Sequence
|
>546 bp
ATGGGCAATATCTTTGGAAACCTTCTCAAGAGCCTGATTGGGAAGAAGGAGATGCGCATC
CTGATGGTGGGCCTGGATGCCGCAGGAAAGACCACCATCCTATACAAGCTGAAACTGGGG
GAGATCGTCACCACCATCCCTACCATTGGGTTCAATGTGGAGACAGTGGAGTATAAGAAC
ATCAGCTTTACAGTGTGGGATGTGGGTGGCCAGGACAAGATTCGACCCCTCTGGAGACAC
TACTTCCAGAACACCCAAGGGTTGATATTTGTGGTCGACAGCAATGATCGGGAGCGAGTA
AATGAGGCCCGGGAAGAGCTGATGAGAATGCTGGCGGAGGACGAGCTCCGGGATGCTGTA
CTCCTTGTCTTTGCAAACAAACAGGATCTGCCTAATGCTATGAACGCTGCTGAGATCACA
GACAAGCTGGGCCTGCATTCCCTTCGTCACCGTAACTGGTACATTCAGGCCACCTGTGCC
ACCAGCGGGGACGGGCTGTACGAAGGCCTGGACTGGCTGGCCAATCAGCTCAAAAACAAG
AAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 181 |
| Molecular Weight
| 20600.6 |
| Theoretical pI
| 7.59 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>ADP-ribosylation factor 3
MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK
K
|
| External Links |
|---|
| GenBank ID Protein
| 20147657 |
| UniProtKB/Swiss-Prot ID
| P61204 |
| UniProtKB/Swiss-Prot Entry Name
| ARF3_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF493882 |
| GeneCard ID
| ARF3 |
| GenAtlas ID
| ARF3 |
| HGNC ID
| HGNC:654 |
| References |
|---|
| General References
| Not Available |