Identification |
HMDB Protein ID
| CDBP03511 |
Secondary Accession Numbers
| Not Available |
Name
| tRNA wybutosine-synthesizing protein 1 homolog B |
Description
| Not Available |
Synonyms
|
- Radical S-adenosyl methionine and flavodoxin domain-containing protein 2
|
Gene Name
| TYW1B |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in iron ion binding |
Specific Function
| Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA |
GO Classification
|
Function |
ion binding |
cation binding |
metal ion binding |
binding |
nucleotide binding |
catalytic activity |
transition metal ion binding |
metal cluster binding |
iron-sulfur cluster binding |
iron ion binding |
fmn binding |
oxidoreductase activity |
Process |
metabolic process |
oxidation reduction |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:7 |
Locus
| 7q11.23 |
SNPs
| TYW1B |
Gene Sequence
|
>2007 bp
ATGGATCCTTCTGCGGATACATGGGACCTCTCCTCACCTTTAATATCATTATGGATAAAC
AGGTTTTACATTTATCTGGGCTTTGCTGTTAGCATTAGCCTTTGGATTTGTGTCCAGATT
GTCATCGAGATGCAGGGATTTGCAACAGTTCTTGCTGAAGCAGTTACGTCCCTGGATCTG
CCTGTGGCCATTATTAATCTAAAAGAATATGATCCAGATGATCATCTGATAGAAGAGGTG
ACTAGTAAAAATGTCTGTGTCTTCCTGGTTGCGACATACACTGACGGCCTACCAACCGAA
AGTGCAGAGTGGTTCTGCAAATGGTTAGAGGAAGCATCCATTGATTTTCGATTTGGCAAA
ACTTACCTGAAGGGTATGAGAGATGCGGTATTTGGCCTGGGAAATTCTGCCTATGCTAGC
CACTTCAACAAGGTTGGCAAAAATGTTGACAAGTGGCTCTGGATGCTTGGCGTGCATCGT
GTGATGAGTCGAGGGGAGGGCGACTGCGACGTGGTTAAAAGCAAGCACGGCAGCATTGAG
GCCAACTTCAGAGCATGGAAGACCAAGTTCATCTCCCAGCTGCAGGCACTTCAGAAAGGG
GAGAGAAAGAAGTCCTGTGGCGGCCACTGCAAGAAAGGCAAATGTGAATCTCACCAACAT
GGCTCAGAGGAGAGGGAGGAAGGATCTCAAGAGCAGGACGAATTGCATCACAGAGACACC
AAGGAGGAAGAACCCTTCGAGAGCTCCAGTGAAGAAGAGTTTGGTGGTGAGGACCATCAG
AGCCTAAATTCCATTGTTGATGTTGAAGATTTGGGCAAAATTATGGATCACGTGAAGAAA
GAAAAGAGAGAAAAGGAACAGCAGGAAGAGAAGTCTGGTTTGTTCAGGAACATGGGGAGG
AATGAAGATGGTGAAAGAAGAGCTATGATAACTCCTGCTCTCCGAGAAGCCCTTACTAAA
CAAGTCGATGCTCCGAGGGAGAGGAGCTTGTTACAAACACACATTCTATGGAATGAGAGC
CATCGCTGCATGGAAACCACCCCGAGCTTGGCGTGTGCTAATAAATGTGTCTTCTGTTGG
TGGCACCACAACAACCCTGTGGGCACTGAATGGTTGTGGAAGATGGACCAGCCTGAAATG
ATCTTGAAGGAAGCCATTGAAAACCATCAGAACATGATTAAGCAGTTTAAAGGAGTACCG
GGCGTCAAAGCAGAACGCTTTGAAGAAGGAATGACGGTAAAGCACTGTGCATTGTCCCTC
GTGGGAGAACCAATAATGTACCCAGAGATCAACAGGTTTTTGAAGCTACTCCACCAGTGT
AAAATCTCCAGCTTCCTGGTCACAAATGCACAATTTCCTGCGGAAATCAGGAACCTCGAG
CCAGTTACTCAGCTGTATGTCAGTGTGGATGCCAGTACCAAAGACAGCCTGAAGAAAATC
GACCGCCCACTCTTCAAGGATTTCTGGCAGCAATTCCTTGACAGTTTAAAAGCCTTGGCA
GTCAAGCAACAACGAACTGTCTACAGACTGACGCTCGTGAAAGCATGGAACGTGGACGAG
CTCCAGGCCTACGCGCAGCTCGTGTCCCTGGGGAATCCTGACTTCATCGAAGTGAAGGGC
GTTACCTACTGCAGAGAAAGTTCAGCAAGCAGTCTTACCATGGCCCATGTGCCCTGGCAT
GAGGAAGTGGTACAGTTTGTCCGCGAGCTGGTGGATCTGATCCCCGAATATGAAATTGCA
TGTGAACACGAACACTCTAATTGCCTCCTGATAGCACACAGAAAGTTTAAAATTGGTGGT
GAATGGTGGACATGGATCGATTATAACCGCTTCCAGGAGCTCATCCAGGAATATGAAGAT
AGTGGTGGATCAAAAACGTTCAGCGCAAAGGATTATATGGCCAGAACTCCTCACTGGGCA
TTATTTGGTGCCAATGAAAGAAGCTTTGATCCCAAGGACACAAGACATCAGAGAAAGAAC
AAATCAAAGGCTATTTCTGGATGTTGA
|
Protein Properties |
Number of Residues
| 668 |
Molecular Weight
| 76945.9 |
Theoretical pI
| 6.22 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>tRNA wybutosine-synthesizing protein 1 homolog B
MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL
PVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGK
TYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIE
ANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDT
KEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGR
NEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPSLACANKCVFCW
WHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSL
VGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKI
DRPLFKDFWQQFLDSLKALAVKQQRTVYRLMLVKAWNVDELQAYAQLVSLGNPDFIEVKG
VTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKFKIGG
EWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKN
KSKAISGC
|
External Links |
GenBank ID Protein
| 224282123 |
UniProtKB/Swiss-Prot ID
| Q6NUM6 |
UniProtKB/Swiss-Prot Entry Name
| TYW1B_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001145440.1 |
GeneCard ID
| TYW1B |
GenAtlas ID
| TYW1B |
HGNC ID
| HGNC:33908 |
References |
General References
| Not Available |