Identification |
HMDB Protein ID
| CDBP03491 |
Secondary Accession Numbers
| Not Available |
Name
| Protein MTO1 homolog, mitochondrial |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| MTO1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in FAD or FADH2 binding |
Specific Function
| Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs |
GO Classification
|
Function |
binding |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
fad or fadh2 binding |
Process |
rna metabolic process |
ncrna metabolic process |
trna metabolic process |
trna processing |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
|
Cellular Location
|
- Mitochondrion
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6q13 |
SNPs
| MTO1 |
Gene Sequence
|
>2154 bp
ATGTTCTACTTCCGAGGCTGTGGCCGTTGGGTCGCGGTTTCCTTCACCAAGCAGCAATTT
CCGTTGGCACGGTTGAGCAGTGACAGCGCGGCGCCCCGGACTCCGCACTTCGACGTGATA
GTCATTGGTGGAGGACATGCCGGGACTGAGGCAGCCACCGCCGCCGCTCGGTGCGGCTCT
CGGACTCTGCTCCTCACTCACCGCGTGGACACGATCGGTCAGATGTCATGTAATCCTTCC
TTTGGTGGCATCGGAAAGGGACATTTAATGAGGGAAGTAGATGCCTTGGATGGCCTGTGT
TCTCGCATCTGTGACCAGTCTGGTGTACATTATAAAGTATTAAACCGGCGTAAGGGACCA
GCTGTGTGGGGTCTGAGAGCTCAGATTGATAGGAAACTCTATAAACAGAACATGCAGAAA
GAAATCTTGAATACACCACTGCTTACTGTTCAGGAGGGAGCTGTAGAAGATCTTATTCTT
ACAGAACCAGAGCCTGAACACACTGGGAAATGCCGTGTCAGTGGGGTTGTTTTGGTGGAT
GGAAGCACAGTATATGCAGAGAGTGTGATTCTGACTACTGGGACATTTCTGAGAGGCATG
ATTGTAATTGGATTGGAGACGCATCCAGCAGGACGTTTAGGGGATCAGCCTTCTATAGGA
TTGGCTCAGACACTGGAGAAGTTAGGGTTTGTGGTGGGAAGGTTGAAGACTGGGACTCCA
CCCCGAATTGCCAAAGAGTCCATTAATTTCAGTATTCTAAACAAGCATATACCGGACAAT
CCATCCATACCATTCAGCTTTACCAATGAGACAGTATGGATTAAGCCAGAAGATCAGCTG
CCATGTTACTTGACTCACACCAACCCTAGAGTGGATGAGATTGTCCTTAAGAACCTTCAC
CTTAATAGTCATGTTAAAGAAACGACAAGAGGACCTCGATACTGTCCCTCCATTGAATCA
AAAGTTTTGCGTTTTCCAAACCGTCTACATCAGGTTTGGTTGGAACCTGAAGGAATGGAT
TCTGACCTTATCTACCCACAGGGGTTATCTATGACGCTACCAGCTGAGTTACAAGAGAAA
ATGATCACATGCATCAGAGGCTTGGAGAAAGCTAAAGTGATTCAGCCAGACGGAGTTTTG
CTCTTGTTGCCCAGGATGGAGTGCAATGGTGCGATCTCGGCTCACCACAACCTCCCCCTG
CCAGGCTACGGTGTTCAGTATGATTACTTAGATCCCCGTCAGATCACCCCTTCCTTGGAG
ACTCATTTGGTTCAACGACTCTTCTTTGCTGGACAGATCAATGGCACCACTGGTTATGAG
GAAGCTGCAGCTCAAGGTGTGATAGCCGGAATCAACGCCAGTCTTCGGGTCAGTCGCAAG
CCTCCCTTTGTGGTTAGCCGAACAGAAGGTTACATAGGAGTCTTGATTGATGACCTCACT
ACTCTGGGCACCAGTGAACCATACCGCATGTTTACCAGCCGAGTAGAGTTCCGTTTGTCA
CTGCGCCCTGATAATGCTGACAGCCGGCTCACACTGCGAGGGTATAAAGACGCTGGCTGT
GTGTCCCAACAACGATATGAAAGAGCTTGTTGGATGAAGTCTTCTTTAGAAGAAGGCATT
TCTGTGTTGAAATCTATTGAGTTTTTGAGCTCTAAATGGAAAAAATTAATCCCAGAGGCT
TCTATAAGTACTAGTAGAAGTCTGCCTGTCAGAGCTCTCGATGTTCTGAAGTATGAGGAA
GTTGACATGGATTCATTAGCCAAGGCTGTTCCAGAGCCCTTGAAGAAGTATACTAAATGT
AGAGAGCTGGCTGAAAGACTGAAAATAGAAGCCACTTATGAATCAGTGTTGTTCCATCAA
CTACAAGAAATAAAGGGAGTTCAGCAAGATGAAGCTCTCCAACTGCCAAAAGACCTAGAT
TATTTGACTATCAGGGATGTGTCTTTGTCCCATGAAGTTCGAGAGAAACTACATTTTAGT
CGTCCACAGACGATCGGGGCTGCTAGTCGCATACCCGGAGTAACACCTGCCGCCATCATC
AATCTGCTGAGATTTGTGAAGACCACTCAACGAAGACAGTCGGCTATGAATGAATCATCC
AAGACTGATCAATACTTATGTGATGCAGACAGACTTCAAGAGAGAGAGTTATAG
|
Protein Properties |
Number of Residues
| 717 |
Molecular Weight
| 79963.2 |
Theoretical pI
| 8.41 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Protein MTO1 homolog, mitochondrial
MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE
THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT
TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI
SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC
RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS
RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
|
External Links |
GenBank ID Protein
| 19882217 |
UniProtKB/Swiss-Prot ID
| Q9Y2Z2 |
UniProtKB/Swiss-Prot Entry Name
| MTO1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_133645.2 |
GeneCard ID
| MTO1 |
GenAtlas ID
| MTO1 |
HGNC ID
| HGNC:19261 |
References |
General References
| Not Available |