Identification
HMDB Protein ID CDBP03491
Secondary Accession Numbers Not Available
Name Protein MTO1 homolog, mitochondrial
Description Not Available
Synonyms Not Available
Gene Name MTO1
Protein Type Enzyme
Biological Properties
General Function Involved in FAD or FADH2 binding
Specific Function Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs
GO Classification
Function
binding
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
fad or fadh2 binding
Process
rna metabolic process
ncrna metabolic process
trna metabolic process
trna processing
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
Cellular Location
  1. Mitochondrion
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6q13
SNPs MTO1
Gene Sequence
>2154 bp
ATGTTCTACTTCCGAGGCTGTGGCCGTTGGGTCGCGGTTTCCTTCACCAAGCAGCAATTT
CCGTTGGCACGGTTGAGCAGTGACAGCGCGGCGCCCCGGACTCCGCACTTCGACGTGATA
GTCATTGGTGGAGGACATGCCGGGACTGAGGCAGCCACCGCCGCCGCTCGGTGCGGCTCT
CGGACTCTGCTCCTCACTCACCGCGTGGACACGATCGGTCAGATGTCATGTAATCCTTCC
TTTGGTGGCATCGGAAAGGGACATTTAATGAGGGAAGTAGATGCCTTGGATGGCCTGTGT
TCTCGCATCTGTGACCAGTCTGGTGTACATTATAAAGTATTAAACCGGCGTAAGGGACCA
GCTGTGTGGGGTCTGAGAGCTCAGATTGATAGGAAACTCTATAAACAGAACATGCAGAAA
GAAATCTTGAATACACCACTGCTTACTGTTCAGGAGGGAGCTGTAGAAGATCTTATTCTT
ACAGAACCAGAGCCTGAACACACTGGGAAATGCCGTGTCAGTGGGGTTGTTTTGGTGGAT
GGAAGCACAGTATATGCAGAGAGTGTGATTCTGACTACTGGGACATTTCTGAGAGGCATG
ATTGTAATTGGATTGGAGACGCATCCAGCAGGACGTTTAGGGGATCAGCCTTCTATAGGA
TTGGCTCAGACACTGGAGAAGTTAGGGTTTGTGGTGGGAAGGTTGAAGACTGGGACTCCA
CCCCGAATTGCCAAAGAGTCCATTAATTTCAGTATTCTAAACAAGCATATACCGGACAAT
CCATCCATACCATTCAGCTTTACCAATGAGACAGTATGGATTAAGCCAGAAGATCAGCTG
CCATGTTACTTGACTCACACCAACCCTAGAGTGGATGAGATTGTCCTTAAGAACCTTCAC
CTTAATAGTCATGTTAAAGAAACGACAAGAGGACCTCGATACTGTCCCTCCATTGAATCA
AAAGTTTTGCGTTTTCCAAACCGTCTACATCAGGTTTGGTTGGAACCTGAAGGAATGGAT
TCTGACCTTATCTACCCACAGGGGTTATCTATGACGCTACCAGCTGAGTTACAAGAGAAA
ATGATCACATGCATCAGAGGCTTGGAGAAAGCTAAAGTGATTCAGCCAGACGGAGTTTTG
CTCTTGTTGCCCAGGATGGAGTGCAATGGTGCGATCTCGGCTCACCACAACCTCCCCCTG
CCAGGCTACGGTGTTCAGTATGATTACTTAGATCCCCGTCAGATCACCCCTTCCTTGGAG
ACTCATTTGGTTCAACGACTCTTCTTTGCTGGACAGATCAATGGCACCACTGGTTATGAG
GAAGCTGCAGCTCAAGGTGTGATAGCCGGAATCAACGCCAGTCTTCGGGTCAGTCGCAAG
CCTCCCTTTGTGGTTAGCCGAACAGAAGGTTACATAGGAGTCTTGATTGATGACCTCACT
ACTCTGGGCACCAGTGAACCATACCGCATGTTTACCAGCCGAGTAGAGTTCCGTTTGTCA
CTGCGCCCTGATAATGCTGACAGCCGGCTCACACTGCGAGGGTATAAAGACGCTGGCTGT
GTGTCCCAACAACGATATGAAAGAGCTTGTTGGATGAAGTCTTCTTTAGAAGAAGGCATT
TCTGTGTTGAAATCTATTGAGTTTTTGAGCTCTAAATGGAAAAAATTAATCCCAGAGGCT
TCTATAAGTACTAGTAGAAGTCTGCCTGTCAGAGCTCTCGATGTTCTGAAGTATGAGGAA
GTTGACATGGATTCATTAGCCAAGGCTGTTCCAGAGCCCTTGAAGAAGTATACTAAATGT
AGAGAGCTGGCTGAAAGACTGAAAATAGAAGCCACTTATGAATCAGTGTTGTTCCATCAA
CTACAAGAAATAAAGGGAGTTCAGCAAGATGAAGCTCTCCAACTGCCAAAAGACCTAGAT
TATTTGACTATCAGGGATGTGTCTTTGTCCCATGAAGTTCGAGAGAAACTACATTTTAGT
CGTCCACAGACGATCGGGGCTGCTAGTCGCATACCCGGAGTAACACCTGCCGCCATCATC
AATCTGCTGAGATTTGTGAAGACCACTCAACGAAGACAGTCGGCTATGAATGAATCATCC
AAGACTGATCAATACTTATGTGATGCAGACAGACTTCAAGAGAGAGAGTTATAG
Protein Properties
Number of Residues 717
Molecular Weight 79963.2
Theoretical pI 8.41
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Protein MTO1 homolog, mitochondrial
MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE
THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT
TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI
SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC
RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS
RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
GenBank ID Protein 19882217
UniProtKB/Swiss-Prot ID Q9Y2Z2
UniProtKB/Swiss-Prot Entry Name MTO1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_133645.2
GeneCard ID MTO1
GenAtlas ID MTO1
HGNC ID HGNC:19261
References
General References Not Available