| Identification |
|---|
| HMDB Protein ID
| CDBP03482 |
| Secondary Accession Numbers
| Not Available |
| Name
| tRNA-dihydrouridine synthase 4-like |
| Description
| Not Available |
| Synonyms
|
- pp35
|
| Gene Name
| DUS4L |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs |
| GO Classification
|
| Function |
| oxidoreductase activity, acting on the ch-ch group of donors |
| binding |
| catalytic activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| oxidoreductase activity |
| fad or fadh2 binding |
| trna dihydrouridine synthase activity |
| Process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
| oxidation reduction |
| rna metabolic process |
| ncrna metabolic process |
| trna metabolic process |
| trna processing |
| metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q22-q31 |
| SNPs
| DUS4L |
| Gene Sequence
|
>954 bp
ATGAAGAGTGACTGCATGCAAACGACAATATGTCAGGAAAGAAAAAAAGATCCCATAGAA
ATGTTTCATTCTGGACAGCTGGTAAAAGTCTGTGCCCCAATGGTTCGATATTCAAAGTTG
GCTTTTAGGACACTAGTAAGAAAATATAGTTGTGATCTGTGTTACACACCAATGATTGTT
GCCGCTGATTTTGTCAAATCTATAAAAGCCAGAGACAGCGAATTTACCACAAATCAAGGT
GATTGCCCATTGATTGTTCAGTTTGCTGCTAACGATGCAAGACTTTTATCTGATGCTGCT
CGTATAGTCTGTCCTTATGCGAATGGAATAGACATTAACTGTGGTTGCCCTCAGAGGTGG
GCAATGGCAGAAGGTTATGGGGCTTGCTTAATAAACAAGCCAGAGCTTGTTCAAGACATG
GTGAAACAAGTAAGAAATCAAGTGGAAACCCCTGGATTTTCAGTTTCTATTAAAATAAGG
ATCCATGATGACCTTAAAAGAACTGTAGATCTTTGTCAAAAGGCTGAAGCAACAGGAGTT
TCATGGATTACAGTCCATGGAAGAACTGCTGAAGAAAGACATCAGCCAGTGCACTATGAT
TCCATTAAAATAATTAAGGAAAATATGTCTATACCTGTAATTGCTAATGGAGACATCAGA
AGCTTAAAGGAAGCAGAAAATGTGTGGCGGATTACTGGGACAGATGGTGTGATGGTTGCA
AGAGGACTCTTAGCAAACCCGGCCATGTTTGCTGGATATGAGGAAACCCCACTGAAATGC
ATCTGGGACTGGGTTGACATTGCTCTTGAACTCGGGACTCCTTACATGTGTTTCCATCAA
CATTTAATGTACATGATGGAAAAGATAACTTCAAGGCAGGAAAAAAGGGTATTTAATGCT
CTGTCAAGCACATCAGCAATCATAGATTACCTTACAGACCATTATGGCATTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 317 |
| Molecular Weight
| 35816.2 |
| Theoretical pI
| 7.37 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>tRNA-dihydrouridine synthase 4-like
MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIV
AADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRW
AMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGV
SWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVA
RGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNA
LSSTSAIIDYLTDHYGI
|
| External Links |
|---|
| GenBank ID Protein
| 31742496 |
| UniProtKB/Swiss-Prot ID
| O95620 |
| UniProtKB/Swiss-Prot Entry Name
| DUS4L_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_181581.1 |
| GeneCard ID
| DUS4L |
| GenAtlas ID
| DUS4L |
| HGNC ID
| HGNC:21517 |
| References |
|---|
| General References
| Not Available |