Identification |
HMDB Protein ID
| CDBP03465 |
Secondary Accession Numbers
| Not Available |
Name
| Lysyl oxidase homolog 3 |
Description
| Not Available |
Synonyms
|
- Lysyl oxidase-like protein 3
|
Gene Name
| LOXL3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in copper ion binding |
Specific Function
| Not Available |
GO Classification
|
Component |
membrane |
cell part |
Function |
scavenger receptor activity |
oxidoreductase activity, acting on the ch-nh2 group of donors |
oxidoreductase activity, acting on the ch-nh2 group of donors, oxygen as acceptor |
molecular transducer activity |
signal transducer activity |
oxidoreductase activity |
copper ion binding |
ion binding |
cation binding |
metal ion binding |
binding |
catalytic activity |
transition metal ion binding |
receptor activity |
transmembrane receptor activity |
Process |
metabolic process |
oxidation reduction |
|
Cellular Location
|
- Secreted
- extracellular space (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 2p13 |
SNPs
| LOXL3 |
Gene Sequence
|
>2262 bp
ATGCGACCTGTCAGTGTCTGGCAGTGGAGCCCCTGGGGGCTGCTGCTGTGCCTGCTGTGC
AGTTCGTGCTTGGGGTCTCCGTCCCCTTCCACGGGCCCTGAGAAGAAGGCCGGGAGCCAG
GGGCTTCGGTTCCGGCTGGCTGGCTTCCCCAGGAAGCCCTACGAGGGCCGCGTGGAGATA
CAGCGAGCTGGTGAATGGGGCACCATCTGCGATGATGACTTCACGCTGCAGGCTGCCCAC
ATCCTCTGCCGGGAGCTGGGCTTCACAGAGGCCACAGGCTGGACCCACAGTGCCAAATAT
GGCCCTGGAACAGGCCGCATCTGGCTGGACAACTTGAGCTGCAGTGGGACCGAGCAGAGT
GTGACTGAATGTGCCTCCCGGGGCTGGGGGAACAGTGACTGTACGCACGATGAGGATGCT
GGGGTCATCTGCAAAGACCAGCGCCTCCCTGGCTTCTCGGACTCCAATGTCATTGAGGTA
GAGCATCACCTGCAAGTGGAGGAGGTGCGAATTCGACCCGCCGTTGGGTGGGGCAGACGA
CCCCTGCCCGTGACGGAGGGGCTGGTGGAAGTCAGGCTTCCTGACGGCTGGTCGCAAGTG
TGCGACAAAGGCTGGAGCGCCCACAACAGCCACGTGGTCTGCGGGATGCTGGGCTTCCCC
AGCGAAAAGAGGGTCAACGCGGCCTTCTACAGGCTGCTAGCCCAACGGCAGCAACACTCC
TTTGGTCTGCATGGGGTGGCGTGCGTGGGCACGGAGGCCCACCTCTCCCTCTGTTCCCTG
GAGTTCTATCGTGCCAATGACACCGCCAGGTGCCCTGGGGGGGGCCCTGCAGTGGTGAGC
TGTGTGCCAGGCCCTGTCTACGCGGCATCCAGTGGCCAGAAGAAGCAACAACAGTCGAAG
CCTCAGGGGGAGGCCCGTGTCCGTCTAAAGGGCGGCGCCCACCCTGGAGAGGGCCGGGTA
GAAGTCCTGAAGGCCAGCACATGGGGCACAGTCTGTGACCGCAAGTGGGACCTGCATGCA
GCCAGCGTGGTGTGTCGGGAGCTGGGCTTCGGGAGTGCTCGAGAAGCTCTGAGTGGCGCT
CGCATGGGGCAGGGCATGGGTGCTATCCACCTGAGTGAAGTTCGCTGCTCTGGACAGGAG
CTCTCCCTCTGGAAGTGCCCCCACAAGAACATCACAGCTGAGGATTGTTCACATAGCCAG
GATGCCGGGGTCCGGTGCAACCTACCTTACACTGGGGCAGAGACCAGGATCCGACTCAGT
GGGGGCCGCAGCCAACATGAGGGGCGAGTCGAGGTGCAAATAGGGGGACCTGGGCCCCTT
CGCTGGGGCCTCATCTGTGGGGATGACTGGGGGACCCTGGAGGCCATGGTGGCCTGTAGG
CAACTGGGTCTGGGCTACGCCAACCACGGCCTGCAGGAGACCTGGTACTGGGACTCTGGG
AATATAACAGAGGTGGTGATGAGTGGAGTGCGCTGCACAGGGACTGAGCTGTCCCTGGAT
CAGTGTGCCCATCATGGCACCCACATCACCTGCAAGAGGACAGGGACCCGCTTCACTGCT
GGAGTCATCTGTTCTGAGACTGCATCAGATCTGTTGCTGCACTCAGCACTGGTGCAGGAG
ACCGCCTACATCGAAGACCGGCCCCTGCATATGTTGTACTGTGCTGCGGAAGAGAACTGC
CTGGCCAGCTCAGCCCGCTCAGCCAACTGGCCCTATGGTCACCGGCGTCTGCTCCGATTC
TCCTCCCAGATCCACAACCTGGGACGAGCTGACTTCAGGCCCAAGGCTGGGCGCCACTCC
TGGGTGTGGCACGAGTGCCATGGGCATTACCACAGCATGGACATCTTCACTCACTATGAT
ATCCTCACCCCAAATGGCACCAAGGTGGCTGAGGGCCACAAAGCTAGTTTCTGTCTCGAA
GACACTGAGTGTCAGGAGGATGTCTCCAAGCGGTATGAGTGTGCCAACTTTGGAGAGCAA
GGCATCACTGTGGGTTGCTGGGATCTCTACCGGCATGACATTGACTGTCAGTGGATTGAC
ATCACGGATGTGAAGCCAGGAAACTACATTCTCCAGGTTGTCATCAACCCAAACTTTGAA
GTAGCAGAGAGTGACTTTACCAACAATGCAATGAAATGTAACTGCAAATATGATGGACAT
AGAATCTGGGTGCACAACTGCCACATTGGTGATGCCTTCAGTGAAGAGGCCAACAGGAGG
TTTGAACGCTACCCTGGCCAGACCAGCAACCAGATTATCTAA
|
Protein Properties |
Number of Residues
| 753 |
Molecular Weight
| 83165.9 |
Theoretical pI
| 6.85 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Lysyl oxidase homolog 3
MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRR
PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS
FGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK
PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA
RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLS
GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG
NITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQE
TAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHS
WVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQ
GITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGH
RIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
|
External Links |
GenBank ID Protein
| 14009597 |
UniProtKB/Swiss-Prot ID
| P58215 |
UniProtKB/Swiss-Prot Entry Name
| LOXL3_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF282619 |
GeneCard ID
| LOXL3 |
GenAtlas ID
| LOXL3 |
HGNC ID
| HGNC:13869 |
References |
General References
| Not Available |