Showing Protein Lysyl oxidase homolog 1 (CDBP03463)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03463
Secondary Accession Numbers Not Available
Name Lysyl oxidase homolog 1
Description Not Available
Synonyms
  1. LOL
  2. Lysyl oxidase-like protein 1
Gene Name LOXL1
Protein Type Enzyme
Biological Properties
General Function Involved in copper ion binding
Specific Function Active on elastin and collagen substrates
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
catalytic activity
transition metal ion binding
oxidoreductase activity, acting on the ch-nh2 group of donors
oxidoreductase activity, acting on the ch-nh2 group of donors, oxygen as acceptor
oxidoreductase activity
copper ion binding
Process
metabolic process
oxidation reduction
Cellular Location
  1. Secreted
  2. extracellular space (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 15q24-q25|15q22
SNPs LOXL1
Gene Sequence 
>1725 bp
ATGGCTCTGGCCCGAGGCAGCCGGCAGCTGGGGGCCCTGGTGTGGGGCGCCTGCCTGTGC
GTGCTGGTGCACGGGCAGCAGGCGCAGCCCGGGCAGGGCTCGGACCCCGCCCGCTGGCGG
CAGCTGATCCAGTGGGAGAACAACGGGCAGGTGTACAGCTTGCTCAACTCGGGCTCAGAG
TACGTGCCGGCCGGACCTCAGCGCTCCGAGAGTAGCTCCCGGGTGCTGCTGGCCGGCGCG
CCCCAGGCCCAGCAGCGGCGCAGCCACGGGAGCCCCCGGCGTCGGCAGGCGCCGTCCCTG
CCCCTGCCGGGGCGCGTGGGCTCGGACACCGTGCGCGGCCAGGCGCGGCACCCATTCGGC
TTTGGCCAGGTGCCCGACAACTGGCGCGAGGTGGCCGTCGGGGACAGCACGGGCATGGCC
CGGGCCCGCACCTCCGTCTCCCAGCAACGGCACGGGGGCTCCGCCTCCTCGGTCTCGGCT
TCGGCCTTCGCCAGCACCTACCGCCAGCAGCCCTCCTACCCGCAGCAGTTCCCCTACCCG
CAGGCGCCCTTCGTCAGCCAGTACGAGAACTACGACCCCGCGTCGCGGACCTACGACCAG
GGTTTCGTGTACTACCGGCCCGCGGGCGGCGGCGTGGGCGCGGGGGCGGCGGCCGTGGCC
TCGGCGGGGGTCATCTACCCCTACCAGCCCCGGGCGCGCTACGAGGAGTACGGCGGCGGC
GAAGAGCTGCCCGAGTACCCGCCTCAGGGCTTCTACCCGGCCCCCGAGAGGCCCTACGTG
CCGCCGCCGCCGCCGCCCCCCGACGGCCTGGACCGCCGCTACTCGCACAGTCTGTACAGC
GAGGGCACCCCCGGCTTCGAGCAGGCCTACCCTGACCCCGGTCCCGAGGCGGCGCAGGCC
CATGGCGGAGACCCACGCCTGGGCTGGTACCCGCCCTACGCCAACCCGCCGCCCGAGGCG
TACGGGCCGCCGCGCGCGCTGGAGCCGCCCTACCTGCCGGTGCGCAGCTCCGACACGCCC
CCGCCGGGTGGGGAGCGGAACGGCGCGCAGCAGGGCCGCCTCAGCGTGGGCAGCGTGTAC
CGGCCCAACCAGAACGGCCGCGGTCTCCCTGACTTGGTCCCAGACCCCAACTATGTGCAA
GCATCCACTTATGTGCAGAGAGCCCACCTGTACTCCCTGCGCTGTGCTGCGGAGGAGAAG
TGTCTGGCCAGCACAGCCTATGCCCCTGAGGCCACCGACTACGATGTGCGGGTGCTACTG
CGCTTCCCCCAGCGCGTGAAGAACCAGGGCACAGCAGACTTCCTCCCCAACCGGCCACGG
CACACCTGGGAGTGGCACAGCTGCCACCAGCATTACCACAGCATGGACGAGTTCAGCCAC
TACGACCTACTGGATGCAGCCACAGGCAAGAAGGTGGCCGAGGGCCACAAGGCCAGTTTC
TGCCTGGAGGACAGCACCTGTGACTTCGGCAACCTCAAGCGCTATGCATGCACCTCTCAT
ACCCAGGGCCTGAGCCCAGGCTGCTATGACACCTACAATGCGGACATCGACTGCCAGTGG
ATCGACATAACCGACGTGCAGCCTGGGAACTACATCCTCAAGGTGCACGTGAACCCAAAG
TATATTGTTTTGGAGTCTGACTTCACCAACAACGTGGTGAGATGCAACATTCACTACACA
GGTCGCTACGTTTCTGCAACAAACTGCAAAATTGTCCAATCCTGA
Protein Properties
Number of Residues 574
Molecular Weight 63109.3
Theoretical pI 7.55
Pfam Domain Function
Signals
  • ["1-25"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Lysyl oxidase homolog 1
MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE
YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG
FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP
QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG
EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA
HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY
RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL
RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF
CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK
YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
GenBank ID Protein 67782346
UniProtKB/Swiss-Prot ID Q08397
UniProtKB/Swiss-Prot Entry Name LOXL1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_005576.2
GeneCard ID LOXL1
GenAtlas ID LOXL1
HGNC ID HGNC:6665
References
General References Not Available