Identification
HMDB Protein ID CDBP03454
Secondary Accession Numbers Not Available
Name High affinity copper uptake protein 1
Description Not Available
Synonyms
  1. Copper transporter 1
  2. Solute carrier family 31 member 1
  3. hCTR1
Gene Name SLC31A1
Protein Type Transporter
Biological Properties
General Function Involved in copper ion transmembrane transporter activity
Specific Function Involved in high-affinity copper uptake
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
transporter activity
di-, tri-valent inorganic cation transmembrane transporter activity
copper ion transmembrane transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
Process
copper ion transport
establishment of localization
transport
ion transport
cation transport
metal ion transport
transition metal ion transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9q31-q32
SNPs SLC31A1
Gene Sequence
>573 bp
ATGGATCATTCCCACCATATGGGGATGAGCTATATGGACTCCAACAGTACCATGCAACCT
TCTCACCATCACCCAACCACTTCAGCCTCACACTCCCATGGTGGAGGAGACAGCAGCATG
ATGATGATGCCTATGACCTTCTACTTTGGCTTTAAGAATGTGGAACTACTGTTTTCCGGT
TTGGTGATCAATACAGCTGGAGAAATGGCTGGAGCTTTTGTGGCAGTGTTTTTACTAGCA
ATGTTCTATGAAGGACTCAAGATAGCCCGAGAGAGCCTGCTGCGTAAGTCACAAGTCAGC
ATTCGCTACAATTCCATGCCTGTCCCAGGACCAAATGGAACCATCCTTATGGAGACACAC
AAAACTGTTGGGCAACAGATGCTGAGCTTTCCTCACCTCCTGCAAACAGTGCTGCACATC
ATCCAGGTGGTCATAAGCTACTTCCTCATGCTCATCTTCATGACCTACAACGGGTACCTC
TGCATTGCAGTAGCAGCAGGGGCCGGTACAGGATACTTCCTCTTCAGCTGGAAGAAGGCA
GTGGTAGTGGATATCACAGAGCATTGCCATTGA
Protein Properties
Number of Residues 190
Molecular Weight 21090.5
Theoretical pI 7.47
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["62-82", "133-153", "157-177"]
Protein Sequence
>High affinity copper uptake protein 1
MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSG
LVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETH
KTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKA
VVVDITEHCH
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O15431
UniProtKB/Swiss-Prot Entry Name COPT1_HUMAN
PDB IDs Not Available
GenBank Gene ID U83460
GeneCard ID SLC31A1
GenAtlas ID SLC31A1
HGNC ID HGNC:11016
References
General References Not Available