Identification |
HMDB Protein ID
| CDBP03443 |
Secondary Accession Numbers
| Not Available |
Name
| Protein tweety homolog 2 |
Description
| Not Available |
Synonyms
|
- hTTY2
|
Gene Name
| TTYH2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in chloride channel activity |
Specific Function
| Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation |
GO Classification
|
Not Available
|
Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 17q25.1 |
SNPs
| TTYH2 |
Gene Sequence
|
>1605 bp
ATGCAGGCGGCGCGCGTGGACTACATCGCTCCCTGGTGGGTCGTGTGGCTGCACAGCGTC
CCGCACGTCGGCCTGCGCCTGCAGCCCGTGAACAGCACCTTCAGCCCCGGCGACGAGAGT
TACCAGGAGTCGCTGCTGTTCCTGGGGCTGGTGGCCGCCGTCTGCCTGGGCCTGAACCTC
ATCTTCCTTGTGGCTTACCTGGTCTGTGCATGCCACTGCCGGCGGGACGATGCGGTGCAG
ACCAAGCAGCACCACTCCTGCTGCATCACCTGGACGGCCGTGGTGGCCGGGCTCATCTGC
TGTGCTGCGGTGGGCGTTGGTTTCTATGGAAACAGCGAGACCAACGATGGGGCGTACCAG
CTGATGTACTCCTTGGACGATGCCAACCACACCTTCTCTGGGATCGATGCTCTGGTTTCC
GGAACTACCCAGAAGATGAAGGTGGACCTAGAGCAGCACCTGGCCCGGCTCAGTGAGATC
TTTGCTGCCCGGGGCGATTACCTGCAGACCCTGAAGTTCATACAGCAGATGGCGGGCAGC
GTTGTTGTTCAGCTCTCAGGACTGCCCGTGTGGAGGGAGGTCACCATGGAGCTGACCAAG
CTATCCGACCAGACTGGCTACGTGGAGTACTACAGGTGGCTCTCCTACCTCCTGCTCTTT
ATCCTGGACCTGGTCATCTGCCTCATTGCCTGCCTGGGACTGGCCAAGCGCTCCAAGTGT
CTCCTGGCCTCGATGCTGTGCTGTGGGGCACTGAGCCTGCTCCTCAGTTGGGCATCCCTG
GCCGCTGATGGCTCTGCGGCAGTGGCCACCAGTGACTTCTGTGTGGCTCCTGACACCTTC
ATCCTGAACGTCACGGAGGGCCAGATCAGCACAGAGGTGACTCGCTACTACCTGTATTGC
AGCCAGAGTGGAAGCAGCCCCTTCCAGCAGACCCTGACCACCTTCCAGCGCGCACTTACC
ACCATGCAGATCCAGGTCGCGGGGCTGCTGCAGTTTGCCGTGCCCCTCTTCTCCACTGCA
GAGGAAGACCTGCTTGCAATCCAGCTCCTGCTGAACTCCTCAGAGTCCAGCCTTCACCAG
CTGACCGCCATGGTGGACTGCCGAGGGCTGCACAAGGATTATCTGGACGCTCTTGCTGGC
ATCTGCTACGACGGCCTCCAGGGCTTGCTGTACCTTGGCCTCTTCTCCTTCCTGGCCGCC
CTCGCCTTCTCCACCATGATCTGTGCAGGGCCAAGGGCCTGGAAGCACTTCACCACCAGA
AACAGAGACTACGATGACATTGATGATGATGACCCCTTTAACCCCCAAGCCTGGCGCATG
GCGGCTCACAGTCCCCCGAGGGGACAGCTTCACAGCTTCTGCAGCTACAGCAGTGGCCTG
GGAAGTCAGACCAGCCTGCAGCCCCCGGCCCAGACCATCTCCAACGCCCCTGTCTCCGAG
TACATGAACCAAGCCATGCTCTTTGGTAGGAACCCACGCTACGAGAACGTGCCACTAATC
GGGAGAGCCTCCCCTCCGCCTACGTACTCTCCCAGCATGAGAGCCACCTACCTGTCTGTG
GCGGATGAGCACCTGAGGCACTACGGGAATCAGTTTCCAGCCTAA
|
Protein Properties |
Number of Residues
| 534 |
Molecular Weight
| 58771.7 |
Theoretical pI
| 5.68 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["45-65", "88-108", "214-234", "241-261", "389-409"]
|
Protein Sequence
|
>Protein tweety homolog 2
MQAARVDYIAPWWVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNL
IFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQ
LMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGS
VVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKC
LLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYC
SQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQ
LTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTR
NRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSE
YMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA
|
External Links |
GenBank ID Protein
| 53988385 |
UniProtKB/Swiss-Prot ID
| Q9BSA4 |
UniProtKB/Swiss-Prot Entry Name
| TTYH2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_032646.5 |
GeneCard ID
| TTYH2 |
GenAtlas ID
| TTYH2 |
HGNC ID
| HGNC:13877 |
References |
General References
| Not Available |