Identification
HMDB Protein ID CDBP03443
Secondary Accession Numbers Not Available
Name Protein tweety homolog 2
Description Not Available
Synonyms
  1. hTTY2
Gene Name TTYH2
Protein Type Enzyme
Biological Properties
General Function Involved in chloride channel activity
Specific Function Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation
GO Classification Not Available
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 17q25.1
SNPs TTYH2
Gene Sequence
>1605 bp
ATGCAGGCGGCGCGCGTGGACTACATCGCTCCCTGGTGGGTCGTGTGGCTGCACAGCGTC
CCGCACGTCGGCCTGCGCCTGCAGCCCGTGAACAGCACCTTCAGCCCCGGCGACGAGAGT
TACCAGGAGTCGCTGCTGTTCCTGGGGCTGGTGGCCGCCGTCTGCCTGGGCCTGAACCTC
ATCTTCCTTGTGGCTTACCTGGTCTGTGCATGCCACTGCCGGCGGGACGATGCGGTGCAG
ACCAAGCAGCACCACTCCTGCTGCATCACCTGGACGGCCGTGGTGGCCGGGCTCATCTGC
TGTGCTGCGGTGGGCGTTGGTTTCTATGGAAACAGCGAGACCAACGATGGGGCGTACCAG
CTGATGTACTCCTTGGACGATGCCAACCACACCTTCTCTGGGATCGATGCTCTGGTTTCC
GGAACTACCCAGAAGATGAAGGTGGACCTAGAGCAGCACCTGGCCCGGCTCAGTGAGATC
TTTGCTGCCCGGGGCGATTACCTGCAGACCCTGAAGTTCATACAGCAGATGGCGGGCAGC
GTTGTTGTTCAGCTCTCAGGACTGCCCGTGTGGAGGGAGGTCACCATGGAGCTGACCAAG
CTATCCGACCAGACTGGCTACGTGGAGTACTACAGGTGGCTCTCCTACCTCCTGCTCTTT
ATCCTGGACCTGGTCATCTGCCTCATTGCCTGCCTGGGACTGGCCAAGCGCTCCAAGTGT
CTCCTGGCCTCGATGCTGTGCTGTGGGGCACTGAGCCTGCTCCTCAGTTGGGCATCCCTG
GCCGCTGATGGCTCTGCGGCAGTGGCCACCAGTGACTTCTGTGTGGCTCCTGACACCTTC
ATCCTGAACGTCACGGAGGGCCAGATCAGCACAGAGGTGACTCGCTACTACCTGTATTGC
AGCCAGAGTGGAAGCAGCCCCTTCCAGCAGACCCTGACCACCTTCCAGCGCGCACTTACC
ACCATGCAGATCCAGGTCGCGGGGCTGCTGCAGTTTGCCGTGCCCCTCTTCTCCACTGCA
GAGGAAGACCTGCTTGCAATCCAGCTCCTGCTGAACTCCTCAGAGTCCAGCCTTCACCAG
CTGACCGCCATGGTGGACTGCCGAGGGCTGCACAAGGATTATCTGGACGCTCTTGCTGGC
ATCTGCTACGACGGCCTCCAGGGCTTGCTGTACCTTGGCCTCTTCTCCTTCCTGGCCGCC
CTCGCCTTCTCCACCATGATCTGTGCAGGGCCAAGGGCCTGGAAGCACTTCACCACCAGA
AACAGAGACTACGATGACATTGATGATGATGACCCCTTTAACCCCCAAGCCTGGCGCATG
GCGGCTCACAGTCCCCCGAGGGGACAGCTTCACAGCTTCTGCAGCTACAGCAGTGGCCTG
GGAAGTCAGACCAGCCTGCAGCCCCCGGCCCAGACCATCTCCAACGCCCCTGTCTCCGAG
TACATGAACCAAGCCATGCTCTTTGGTAGGAACCCACGCTACGAGAACGTGCCACTAATC
GGGAGAGCCTCCCCTCCGCCTACGTACTCTCCCAGCATGAGAGCCACCTACCTGTCTGTG
GCGGATGAGCACCTGAGGCACTACGGGAATCAGTTTCCAGCCTAA
Protein Properties
Number of Residues 534
Molecular Weight 58771.7
Theoretical pI 5.68
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["45-65", "88-108", "214-234", "241-261", "389-409"]
Protein Sequence
>Protein tweety homolog 2
MQAARVDYIAPWWVVWLHSVPHVGLRLQPVNSTFSPGDESYQESLLFLGLVAAVCLGLNL
IFLVAYLVCACHCRRDDAVQTKQHHSCCITWTAVVAGLICCAAVGVGFYGNSETNDGAYQ
LMYSLDDANHTFSGIDALVSGTTQKMKVDLEQHLARLSEIFAARGDYLQTLKFIQQMAGS
VVVQLSGLPVWREVTMELTKLSDQTGYVEYYRWLSYLLLFILDLVICLIACLGLAKRSKC
LLASMLCCGALSLLLSWASLAADGSAAVATSDFCVAPDTFILNVTEGQISTEVTRYYLYC
SQSGSSPFQQTLTTFQRALTTMQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQ
LTAMVDCRGLHKDYLDALAGICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTR
NRDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSE
YMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYGNQFPA
GenBank ID Protein 53988385
UniProtKB/Swiss-Prot ID Q9BSA4
UniProtKB/Swiss-Prot Entry Name TTYH2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_032646.5
GeneCard ID TTYH2
GenAtlas ID TTYH2
HGNC ID HGNC:13877
References
General References Not Available