Identification
HMDB Protein ID CDBP03437
Secondary Accession Numbers Not Available
Name Serine/threonine-protein kinase OSR1
Description Not Available
Synonyms
  1. Oxidative stress-responsive 1 protein
Gene Name OXSR1
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton
GO Classification
Function
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
Process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
phosphorus metabolic process
phosphate metabolic process
metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:3
Locus 3p22.2
SNPs OXSR1
Gene Sequence
>1584 bp
ATGTCCGAAGACTCGAGCGCCCTGCCCTGGTCCATCAACAGGGACGATTACGAGCTGCAG
GAGGTGATCGGGAGTGGAGCAACTGCTGTAGTCCAAGCAGCTTATTGTGCCCCTAAAAAG
GAGAAAGTGGCAATCAAACGGATAAACCTTGAGAAATGTCAAACTAGCATGGATGAACTC
CTGAAAGAAATTCAAGCCATGAGTCAATGCCATCATCCTAATATTGTATCTTACTACACA
TCTTTTGTGGTAAAAGATGAGCTGTGGCTTGTCATGAAGCTGCTAAGTGGAGGTTCTGTT
CTGGATATTATTAAGCACATTGTGGCAAAAGGGGAACACAAAAGTGGAGTCCTAGATGAA
TCTACCATTGCTACGATACTCCGAGAAGTACTGGAAGGGCTGGAATATCTGCATAAAAAT
GGACAGATCCACAGAGATGTGAAAGCTGGAAACATTCTTCTTGGAGAAGATGGCTCAGTA
CAGATTGCAGACTTTGGGGTTAGTGCTTTTTTAGCAACTGGTGGTGATATTACCCGAAAT
AAAGTGAGAAAGACCTTTGTTGGCACCCCTTGTTGGATGGCACCTGAAGTTATGGAACAG
GTCCGTGGTTATGATTTCAAAGCTGATATTTGGAGTTTTGGAATTACAGCAATTGAATTG
GCTACAGGGGCGGCTCCTTATCATAAATATCCACCAATGAAGGTTTTAATGCTGACACTG
CAGAACGATCCTCCTTCTTTGGAAACTGGTGTTCAAGATAAAGAAATGCTGAAAAAATAT
GGAAAATCATTTAGAAAAATGATTTCATTGTGCCTTCAAAAAGATCCAGAAAAAAGACCA
ACAGCAGCAGAACTATTAAGGCACAAATTTTTCCAGAAAGCAAAGAATAAAGAATTTCTT
CAAGAAAAAACATTGCAGAGAGCACCAACCATTTCTGAAAGAGCAAAAAAGGTTCGGAGA
GTACCAGGTTCCAGTGGGCGTCTTCATAAGACAGAGGATGGAGGCTGGGAGTGGAGTGAT
GATGAATTTGATGAAGAAAGTGAGGAAGGGAAAGCAGCAATTTCACAACTCAGGTCTCCC
CGAGTGAAAGAATCAATATCAAATTCTGAGCTCTTTCCAACAACTGATCCTGTGGGTACT
TTGCTCCAAGTTCCAGAACAGATCTCTGCTCATCTACCTCAGCCAGCTGGGCAGATTGCT
ACACAGCCAACTCAAGTCTCTCTCCCACCCACCGCAGAGCCAGCAAAAACAGCTCAGGCT
TTGTCTTCAGGATCAGGTTCACAAGAAACCAAGATCCCAATCAGTCTAGTACTAAGATTA
AGGAATTCCAAAAAAGAACTAAATGATATTCGATTTGAATTTACTCCTGGGAGAGATACA
GCAGAGGGTGTCTCTCAGGAACTCATTTCTGCTGGCCTGGTCGACGGAAGGGATTTAGTA
ATAGTGGCAGCTAATTTGCAGAAAATTGTGGAAGAACCTCAGTCAAATCGATCTGTCACT
TTCAAACTGGCATCTGGTGTCGAAGGCTCAGATATTCCTGATGATGGTAAACTGATAGGA
TTTGCCCAGCTCAGCATCAGCTAA
Protein Properties
Number of Residues 527
Molecular Weight 58021.7
Theoretical pI 6.37
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Serine/threonine-protein kinase OSR1
MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDEL
LKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDE
STIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN
KVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTL
QNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFL
QEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSP
RVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQA
LSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLV
IVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
GenBank ID Protein 4519629
UniProtKB/Swiss-Prot ID O95747
UniProtKB/Swiss-Prot Entry Name OXSR1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB017642
GeneCard ID OXSR1
GenAtlas ID OXSR1
HGNC ID HGNC:8508
References
General References Not Available