3426

CDBP03425

Gamma-aminobutyric acid receptor subunit pi

O00591

GBRP_HUMAN

false true

Receptor

Homo_sapiens

GABRP

440

50639.7

6.99

Involved in ion transport

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone

["1-16"]

["243-266", "270-292", "305-327", "417-438"]

U95367

GABRP

Chromosome:5

5q33-q34

GABRP

HGNC:4089

true

2020-06-12T23:07:14Z

2020-07-28T02:28:47Z