| Identification |
|---|
| HMDB Protein ID
| CDBP03411 |
| Secondary Accession Numbers
| Not Available |
| Name
| FXYD domain-containing ion transport regulator 3 |
| Description
| Not Available |
| Synonyms
|
- Chloride conductance inducer protein Mat-8
- Mammary tumor 8 kDa protein
- Phospholemman-like
|
| Gene Name
| FXYD3 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in ion channel activity |
| Specific Function
| Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels |
| GO Classification
|
| Component |
| cell part |
| membrane |
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| transporter activity |
| ion channel activity |
| Process |
| establishment of localization |
| transport |
| ion transport |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.12 |
| SNPs
| FXYD3 |
| Gene Sequence
|
>264 bp
ATGCAGAAGGTGACCCTGGGCCTGCTTGTGTTCCTGGCAGGCTTTCCTGTCCTGGACGCC
AATGACCTAGAAGATAAAAACAGTCCTTTCTACTATGACTGGCACAGCCTCCAGGTTGGC
GGGCTCATCTGCGCTGGGGTTCTGTGCGCCATGGGCATCATCATCGTCATGAGTGCAAAA
TGCAAATGCAAGTTTGGCCAGAAGTCCGGTCACCATCCAGGGGAGACTCCACCTCTCATC
ACCCCAGGCTCAGCCCAAAGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 87 |
| Molecular Weight
| 9262.8 |
| Theoretical pI
| 7.38 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>FXYD domain-containing ion transport regulator 3
MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK
CKCKFGQKSGHHPGETPPLITPGSAQS
|
| External Links |
|---|
| GenBank ID Protein
| 209862817 |
| UniProtKB/Swiss-Prot ID
| Q14802 |
| UniProtKB/Swiss-Prot Entry Name
| FXYD3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001136011.1 |
| GeneCard ID
| FXYD3 |
| GenAtlas ID
| FXYD3 |
| HGNC ID
| HGNC:4027 |
| References |
|---|
| General References
| Not Available |