Identification
HMDB Protein ID CDBP03411
Secondary Accession Numbers Not Available
Name FXYD domain-containing ion transport regulator 3
Description Not Available
Synonyms
  1. Chloride conductance inducer protein Mat-8
  2. Mammary tumor 8 kDa protein
  3. Phospholemman-like
Gene Name FXYD3
Protein Type Transporter
Biological Properties
General Function Involved in ion channel activity
Specific Function Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels
GO Classification
Component
cell part
membrane
Function
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
ion channel activity
Process
establishment of localization
transport
ion transport
Cellular Location
  1. Membrane
  2. Single-pass type I membrane protein (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.12
SNPs FXYD3
Gene Sequence
>264 bp
ATGCAGAAGGTGACCCTGGGCCTGCTTGTGTTCCTGGCAGGCTTTCCTGTCCTGGACGCC
AATGACCTAGAAGATAAAAACAGTCCTTTCTACTATGACTGGCACAGCCTCCAGGTTGGC
GGGCTCATCTGCGCTGGGGTTCTGTGCGCCATGGGCATCATCATCGTCATGAGTGCAAAA
TGCAAATGCAAGTTTGGCCAGAAGTCCGGTCACCATCCAGGGGAGACTCCACCTCTCATC
ACCCCAGGCTCAGCCCAAAGCTGA
Protein Properties
Number of Residues 87
Molecular Weight 9262.8
Theoretical pI 7.38
Pfam Domain Function
Signals
  • ["1-20"]
Transmembrane Regions
  • ["39-59"]
Protein Sequence
>FXYD domain-containing ion transport regulator 3
MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK
CKCKFGQKSGHHPGETPPLITPGSAQS
GenBank ID Protein 209862817
UniProtKB/Swiss-Prot ID Q14802
UniProtKB/Swiss-Prot Entry Name FXYD3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001136011.1
GeneCard ID FXYD3
GenAtlas ID FXYD3
HGNC ID HGNC:4027
References
General References Not Available