Showing Protein Chloride intracellular channel protein 6 (CDBP03409)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP03409
Secondary Accession Numbers Not Available
Name Chloride intracellular channel protein 6
Description Not Available
Synonyms
  1. Parchorin
Gene Name CLIC6
Protein Type Transporter
Biological Properties
General Function Involved in voltage-gated chloride channel activity
Specific Function May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport
GO Classification
Component
membrane
cell part
Function
ion transmembrane transporter activity
transporter activity
ion channel activity
voltage-gated chloride channel activity
anion channel activity
chloride channel activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
Process
establishment of localization
transport
chloride transport
anion transport
inorganic anion transport
ion transport
Cellular Location
  1. Cell membrane
  2. Cytoplasm
  3. Single-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 21q22.12
SNPs CLIC6
Gene Sequence 
>2115 bp
ATGGCCGAGGCCGCGGAGCCGGAGGGGGTTGCCCCGGGTCCCCAGGGGCCGCCGGAGGTC
CCCGCGCCTCTGGCTGAGAGACCCGGAGAGCCAGGAGCCGCGGGCGGGGAGGCAGAAGGG
CCGGAGGGGAGCGAGGGCGCAGAGGAGGCGCCGAGGGGCGCCGCCGCTGTGAAGGAGGCA
GGAGGCGGCGGGCCAGACAGGGGCCCGGAGGCCGAGGCGCGGGGCACGAGGGGGGCGCAC
GGCGAGACTGAGGCCGAGGAGGGAGCCCCGGAGGGTGCCGAGGTGCCCCAAGGAGGGGAG
GAGACAAGCGGCGCGCAGCAGGTGGAGGGGGCGAGCCCGGGACGCGGCGCGCAGGGCGAG
CCCCGCGGGGAGGCTCAGAGGGAGCCCGAGGACTCTGCGGCCCCCGAGAGGCAGGAGGAG
GCGGAGCAGAGGCCTGAGGTCCCGGAAGGTAGCGCGTCCGGGGAGGCGGGGGACAGCGTA
GACGCGGAGGGCCCGCTGGGGGACAACATAGAAGCGGAGGGCCCGGCGGGCGACAGCGTA
GAGGCGGAGGGCCGGGTGGGGGACAGCGTAGACGCGGAAGGTCCGGCGGGGGACAGCGTA
GACGCGGAGGGCCCGCTGGGGGACAACATACAAGCCGAGGGCCCGGCGGGGGACAGCGTA
GACGCGGAGGGCCGGGTGGGGGACAGCGTAGACGCGGAAGGTCCGGCGGGGGACAGCGTA
GACGCGGAGGGCCGGGTGGGGGACAGCGTAGAGGCGGGGGACCCGGCGGGGGACGGCGTA
GAAGCGGGGGTCCCGGCGGGGGACAGCGTAGAAGCCGAAGGCCCGGCGGGGGACAGCATG
GACGCCGAGGGTCCGGCAGGAAGGGCGCGCCGGGTCTCGGGTGAGCCGCAGCAATCGGGG
GACGGCAGCCTCTCGCCCCAGGCCGAGGCAATTGAGGTCGCAGCCGGGGAGAGTGCGGGG
CGCAGCCCCGGTGAGCTCGCCTGGGACGCAGCGGAGGAGGCGGAGGTCCCGGGGGTAAAG
GGGTCCGAAGAAGCGGCCCCCGGGGACGCAAGGGCAGACGCTGGCGAGGACAGGGTAGGG
GATGGGCCACAGCAGGAGCCGGGGGAGGACGAAGAGAGACGAGAGCGGAGCCCGGAGGGG
CCAAGGGAGGAGGAAGCAGCGGGGGGCGAAGAGGAATCCCCCGACAGCAGCCCACATGGG
GAGGCCTCCAGGGGCGCCGCGGAGCCTGAGGCCCAGCTCAGCAACCACCTGGCCGAGGAG
GGCCCCGCCGAGGGTAGCGGCGAGGCCGCGCGCGTGAACGGCCGCCGGGAGGACGGAGAG
GCGTCCGAGCCCCGGGCCCTGGGGCAGGAGCACGACATCACCCTCTTCGTCAAGGTAAAA
CTTACTGCATTAGGCTGTTCTCGCATTGCTATAAAGAAATACCTGAGAGCTGGTTATGAT
GGTGAGAGTATCGGAAATTGCCCGTTTTCTCAGCGTCTCTTTATGATTCTCTGGCTGAAA
GGCGTTATATTTAATGTGACCACAGTGGACCTGAAAAGGAAACCCGCAGACCTGCAGAAC
CTGGCTCCCGGAACAAACCCTCCTTTCATGACTTTTGATGGTGAAGTCAAGACGGATGTG
AATAAGATCGAGGAGTTCTTAGAGGAGAAATTAGCTCCCCCGAGGTATCCCAAGCTGGGG
ACCCAACATCCCGAATCTAATTCCGCAGGAAATGACGTGTTTGCCAAATTCTCAGCGTTT
ATAAAAAACACGAAGAAGGATGCAAATGAGATTCATGAAAAGAACCTGCTGAAGGCCCTG
AGGAAGCTGGATAATTACTTAAATAGCCCTCTGCCTGATGAAATAGATGCCTACAGCACC
GAGGATGTCACTGTTTCTGGAAGGAAGTTTCTGGATGGGGACGAGCTGACGCTGGCTGAC
TGCAACCTCTTACCCAAGCTCCATATTATTAAGATTGTGGCCAAGAAGTACAGAGATTTT
GAATTTCCTTCTGAAATGACTGGCATCTGGAGATACTTGAATAATGCTTATGCTAGAGAT
GAGTTCACAAATACGTGTCCAGCTGATCAAGAGATTGAACACGCATATTCAGATGTTGCA
AAAAGAATGAAATGA
Protein Properties
Number of Residues 704
Molecular Weight 73010.9
Theoretical pI 4.01
Pfam Domain Function Not Available
Signals
  • ["None"]
Transmembrane Regions
  • ["489-509"]
Protein Sequence 
>Chloride intracellular channel protein 6
MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEA
GGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGE
PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSV
EAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSV
DAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSG
DGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVG
DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEE
GPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKVKLTALGCSRIAIKKYLRAGYD
GESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDV
NKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKAL
RKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDF
EFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK
GenBank ID Protein 25990944
UniProtKB/Swiss-Prot ID Q96NY7
UniProtKB/Swiss-Prot Entry Name CLIC6_HUMAN
PDB IDs Not Available
GenBank Gene ID AF448439
GeneCard ID CLIC6
GenAtlas ID CLIC6
HGNC ID HGNC:2065
References
General References Not Available