Identification |
HMDB Protein ID
| CDBP03376 |
Secondary Accession Numbers
| Not Available |
Name
| Ras-related protein Rap-1b |
Description
| Not Available |
Synonyms
|
- GTP-binding protein smg p21B
|
Gene Name
| RAP1B |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in GTP binding |
Specific Function
| GTP-binding protein that possesses intrinsic GTPase activity |
GO Classification
|
Component |
intracellular |
membrane |
cell part |
Function |
purine nucleotide binding |
binding |
nucleotide binding |
catalytic activity |
hydrolase activity |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
gtpase activity |
nucleoside-triphosphatase activity |
hydrolase activity, acting on acid anhydrides |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
pyrophosphatase activity |
Process |
regulation of cellular process |
signal transduction |
intracellular signal transduction |
small gtpase mediated signal transduction |
biological regulation |
regulation of biological process |
|
Cellular Location
|
- Cell membrane
- Cytoplasm
- cytosol
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12q14 |
SNPs
| RAP1B |
Gene Sequence
|
>555 bp
ATGCGTGAGTATAAGCTAGTCGTTCTTGGCTCAGGAGGCGTTGGAAAGTCTGCTTTGACT
GTACAATTTGTTCAAGGAATTTTTGTAGAAAAATACGATCCTACGATAGAAGATTCTTAT
AGAAAGCAAGTTGAAGTAGATGCACAACAGTGTATGCTTGAAATCTTGGATACTGCAGGA
ACGGAGCAATTTACAGCAATGAGGGATTTATACATGAAAAATGGACAAGGATTTGCATTA
GTTTATTCCATCACAGCACAGTCCACATTTAACGATTTACAAGACCTGAGAGAACAGATT
CTTCGAGTTAAAGACACTGATGATGTTCCAATGATTCTTGTTGGTAATAAGTGTGACTTG
GAAGATGAAAGAGTTGTAGGGAAGGAACAAGGTCAAAATCTAGCAAGACAATGGAACAAC
TGTGCATTCTTAGAATCTTCTGCAAAATCAAAAATAAATGTTAATGAGATCTTTTATGAC
CTAGTGCGGCAAATTAACAGAAAAACTCCAGTGCCTGGGAAGGCTCGCAAAAAGTCATCA
TGTCAGCTGCTTTAA
|
Protein Properties |
Number of Residues
| 184 |
Molecular Weight
| 20824.7 |
Theoretical pI
| 5.39 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Ras-related protein Rap-1b
MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
CQLL
|
External Links |
GenBank ID Protein
| 21104380 |
UniProtKB/Swiss-Prot ID
| P61224 |
UniProtKB/Swiss-Prot Entry Name
| RAP1B_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AB062128 |
GeneCard ID
| RAP1B |
GenAtlas ID
| RAP1B |
HGNC ID
| HGNC:9857 |
References |
General References
| Not Available |