| Identification |
|---|
| HMDB Protein ID
| CDBP03373 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phospholemman |
| Description
| Not Available |
| Synonyms
|
- FXYD domain-containing ion transport regulator 1
|
| Gene Name
| FXYD1 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in ion channel activity |
| Specific Function
| Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May have a functional role in muscle contraction |
| GO Classification
|
| Component |
| cell part |
| membrane |
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| transporter activity |
| ion channel activity |
| Process |
| establishment of localization |
| transport |
| ion transport |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.1 |
| SNPs
| FXYD1 |
| Gene Sequence
|
>279 bp
ATGGCGTCTCTTGGCCACATCTTGGTTTTCTGTGTGGGTCTCCTCACCATGGCCAAGGCA
GAAAGTCCAAAGGAACACGACCCGTTCACTTACGACTACCAGTCCCTGCAGATCGGAGGC
CTCGTCATCGCCGGGATCCTCTTCATCCTGGGCATCCTCATCGTGCTGAGCAGAAGATGC
CGGTGCAAGTTCAACCAGCAGCAGAGGACTGGGGAACCCGATGAAGAGGAGGGAACTTTC
CGCAGCTCCATCCGCCGTCTGTCCACCCGCAGGCGGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 92 |
| Molecular Weight
| 10441.0 |
| Theoretical pI
| 9.41 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Phospholemman
MASLGHILVFCVGLLTMAKAESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRC
RCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR
|
| External Links |
|---|
| GenBank ID Protein
| 158260645 |
| UniProtKB/Swiss-Prot ID
| O00168 |
| UniProtKB/Swiss-Prot Entry Name
| PLM_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK289811 |
| GeneCard ID
| FXYD1 |
| GenAtlas ID
| FXYD1 |
| HGNC ID
| HGNC:4025 |
| References |
|---|
| General References
| Not Available |