Showing Protein Potassium voltage-gated channel subfamily H member 3 (CDBP03357)
| Identification | ||||||||||||||||||||||||||||||||||||||||||
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| HMDB Protein ID | CDBP03357 | |||||||||||||||||||||||||||||||||||||||||
| Secondary Accession Numbers | Not Available | |||||||||||||||||||||||||||||||||||||||||
| Name | Potassium voltage-gated channel subfamily H member 3 | |||||||||||||||||||||||||||||||||||||||||
| Description | Not Available | |||||||||||||||||||||||||||||||||||||||||
| Synonyms |
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| Gene Name | KCNH3 | |||||||||||||||||||||||||||||||||||||||||
| Protein Type | Enzyme | |||||||||||||||||||||||||||||||||||||||||
| Biological Properties | ||||||||||||||||||||||||||||||||||||||||||
| General Function | Involved in ion channel activity | |||||||||||||||||||||||||||||||||||||||||
| Specific Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly | |||||||||||||||||||||||||||||||||||||||||
| GO Classification |
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| Cellular Location |
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| Pathways | Not Available | |||||||||||||||||||||||||||||||||||||||||
| Gene Properties | ||||||||||||||||||||||||||||||||||||||||||
| Chromosome Location | Chromosome:1 | |||||||||||||||||||||||||||||||||||||||||
| Locus | 12q13 | |||||||||||||||||||||||||||||||||||||||||
| SNPs | KCNH3 | |||||||||||||||||||||||||||||||||||||||||
| Gene Sequence |
>3252 bp ATGCCGGCCATGCGGGGCCTCCTGGCGCCTCAGAACACCTTCCTGGACACCATCGCTACG CGCTTCGACGGCACGCACAGTAACTTCGTGCTGGGCAACGCCCAGGTGGCGGGGCTCTTC CCCGTGGTCTACTGCTCTGATGGCTTCTGTGACCTCACGGGCTTCTCCCGGGCTGAGGTC ATGCAGCGGGGCTGTGCCTGCTCCTTCCTTTATGGGCCAGACACCAGTGAGCTCGTCCGC CAACAGATCCGCAAGGCCCTGGACGAGCACAAGGAGTTCAAGGCTGAGCTGATCCTGTAC CGGAAGAGCGGGCTCCCGTTCTGGTGTCTCCTGGATGTGATACCCATAAAGAATGAGAAA GGGGAGGTGGCTCTCTTCCTAGTCTCTCACAAGGACATCAGCGAAACCAAGAACCGAGGG GGCCCCGACAGATGGAAGGAGACAGGTGGTGGCCGGCGCCGATATGGCCGGGCACGATCC AAAGGCTTCAATGCCAACCGGCGGCGGAGCCGGGCCGTGCTCTACCACCTGTCCGGGCAC CTGCAGAAGCAGCCCAAGGGCAAGCACAAGCTCAATAAGGGGGTGTTTGGGGAGAAACCA AACTTGCCTGAGTACAAAGTAGCCGCCATCCGGAAGTCGCCCTTCATCCTGTTGCACTGT GGGGCACTGAGAGCCACCTGGGATGGCTTCATCCTGCTCGCCACACTCTATGTGGCTGTC ACTGTGCCCTACAGCGTGTGTGTGAGCACAGCACGGGAGCCCAGTGCCGCCCGCGGCCCG CCCAGCGTCTGTGACCTGGCCGTGGAGGTCCTCTTCATCCTTGACATTGTGCTGAATTTC CGTACCACATTCGTGTCCAAGTCGGGCCAGGTGGTGTTTGCCCCAAAGTCCATTTGCCTC CACTACGTCACCACCTGGTTCCTGCTGGATGTCATCGCAGCGCTGCCCTTTGACCTGCTA CATGCCTTCAAGGTCAACGTGTACTTCGGGGCCCATCTGCTGAAGACGGTGCGCCTGCTG CGCCTGCTGCGCCTGCTTCCGCGGCTGGACCGGTACTCGCAGTACAGCGCCGTGGTGCTG ACACTGCTCATGGCCGTGTTCGCCCTGCTCGCGCACTGGGTCGCCTGCGTCTGGTTTTAC ATTGGCCAGCGGGAGATCGAGAGCAGCGAATCCGAGCTGCCTGAGATTGGCTGGCTGCAG GAGCTGGCCCGCCGACTGGAGACTCCCTACTACCTGGTGGGCCGGAGGCCAGCTGGAGGG AACAGCTCCGGCCAGAGTGACAACTGCAGCAGCAGCAGCGAGGCCAACGGGACGGGGCTG GAGCTGCTGGGCGGCCCGTCGCTGCGCAGCGCCTACATCACCTCCCTCTACTTCGCACTC AGCAGCCTCACCAGCGTGGGCTTCGGCAACGTGTCCGCCAACACGGACACCGAGAAGATC TTCTCCATCTGCACCATGCTCATCGGCGCCCTGATGCACGCGGTGGTGTTTGGGAACGTG ACGGCCATCATCCAGCGCATGTACGCCCGCCGCTTTCTGTACCACAGCCGCACGCGCGAC CTGCGCGACTACATCCGCATCCACCGTATCCCCAAGCCCCTCAAGCAGCGCATGCTGGAG TACTTCCAGGCCACCTGGGCGGTGAACAATGGCATCGACACCACCGAGCTGCTGCAGAGC CTCCCTGACGAGCTGCGCGCAGACATCGCCATGCACCTGCACAAGGAGGTCCTGCAGCTG CCACTGTTTGAGGCGGCCAGCCGCGGCTGCCTGCGGGCACTGTCTCTGGCCCTGCGGCCC GCCTTCTGCACGCCGGGCGAGTACCTCATCCACCAAGGCGATGCCCTGCAGGCCCTCTAC TTTGTCTGCTCTGGCTCCATGGAGGTGCTCAAGGGTGGCACCGTGCTCGCCATCCTAGGG AAGGGCGACCTGATCGGCTGTGAGCTGCCCCGGCGGGAGCAGGTGGTAAAGGCCAATGCC GACGTGAAGGGGCTGACGTACTGCGTCCTGCAGTGTCTGCAGCTGGCTGGCCTGCACGAC AGCCTTGCGCTGTACCCCGAGTTTGCCCCGCGCTTCAGTCGTGGCCTCCGAGGGGAGCTC AGCTACAACCTGGGTGCTGGGGGAGGCTCTGCAGAGGTGGACACCAGCTCCCTGAGCGGC GACAATACCCTTATGTCCACGCTGGAGGAGAAGGAGACAGATGGGGAGCAGGGCCCCACG GTCTCCCCAGCCCCAGCTGATGAGCCCTCCAGCCCCCTGCTGTCCCCTGGCTGCACCTCC TCATCCTCAGCTGCCAAGCTGCTATCCCCACGTCGAACAGCACCCCGGCCTCGTCTAGGT GGCAGAGGGAGGCCAGGCAGGGCAGGGGCTTTGAAGGCTGAGGCTGGCCCCTCTGCTCCC CCACGGGCCCTAGAGGGGCTACGGCTGCCCCCCATGCCATGGAATGTGCCCCCAGATCTG AGCCCCAGGGTAGTAGATGGCATTGAAGACGGCTGTGGCTCGGACCAGCCCAAGTTCTCT TTCCGCGTGGGCCAGTCTGGCCCGGAATGTAGCAGCAGCCCCTCCCCTGGACCAGAGAGC GGCCTGCTCACTGTTCCCCATGGGCCCAGCGAGGCAAGGAACACAGACACACTGGACAAG CTTCGGCAGGCGGTGACAGAGCTGTCAGAGCAGGTGCTGCAGATGCGGGAAGGACTGCAG TCACTTCGCCAGGCTGTGCAGCTTGTCCTGGCGCCCCACAGGGAGGGTCCGTGCCCTCGG GCATCGGGAGAGGGGCCGTGCCCAGCCAGCACCTCCGGGCTTCTGCAGCCTCTGTGTGTG GACACTGGGGCATCCTCCTACTGCCTGCAGCCCCCAGCTGGCTCTGTCTTGAGTGGGACT TGGCCCCACCCTCGTCCGGGGCCTCCTCCCCTCATGGCACCCTGGCCCTGGGGTCCCCCA GCGTCTCAGAGCTCCCCCTGGCCTCGAGCCACAGCTTTCTGGACCTCCACCTCAGACTCA GAGCCCCCTGCCTCAGGAGACCTCTGCTCTGAGCCCAGCACCCCTGCCTCCCCTCCTCCT TCTGAGGAAGGGGCTAGGACTGGGCCCGCAGAGCCTGTGAGCCAGGCTGAGGCTACCAGC ACTGGAGAGCCCCCACCAGGGTCAGGGGGCCTGGCCTTGCCCTGGGACCCCCACAGCCTG GAGATGGTGCTTATTGGCTGCCATGGCTCTGGCACAGTCCAGTGGACCCAGGAAGAAGGC ACAGGGGTCTGA |
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| Protein Properties | ||||||||||||||||||||||||||||||||||||||||||
| Number of Residues | 1083 | |||||||||||||||||||||||||||||||||||||||||
| Molecular Weight | 117127.7 | |||||||||||||||||||||||||||||||||||||||||
| Theoretical pI | 7.98 | |||||||||||||||||||||||||||||||||||||||||
| Pfam Domain Function | ||||||||||||||||||||||||||||||||||||||||||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Potassium voltage-gated channel subfamily H member 3 MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEV MQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEK GEVALFLVSHKDISETKNRGGPDRWKETGGGRRRYGRARSKGFNANRRRSRAVLYHLSGH LQKQPKGKHKLNKGVFGEKPNLPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAV TVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICL HYVTTWFLLDVIAALPFDLLHAFKVNVYFGAHLLKTVRLLRLLRLLPRLDRYSQYSAVVL TLLMAVFALLAHWVACVWFYIGQREIESSESELPEIGWLQELARRLETPYYLVGRRPAGG NSSGQSDNCSSSSEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKI FSICTMLIGALMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLE YFQATWAVNNGIDTTELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRP AFCTPGEYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPRREQVVKANA DVKGLTYCVLQCLQLAGLHDSLALYPEFAPRFSRGLRGELSYNLGAGGGSAEVDTSSLSG DNTLMSTLEEKETDGEQGPTVSPAPADEPSSPLLSPGCTSSSSAAKLLSPRRTAPRPRLG GRGRPGRAGALKAEAGPSAPPRALEGLRLPPMPWNVPPDLSPRVVDGIEDGCGSDQPKFS FRVGQSGPECSSSPSPGPESGLLTVPHGPSEARNTDTLDKLRQAVTELSEQVLQMREGLQ SLRQAVQLVLAPHREGPCPRASGEGPCPASTSGLLQPLCVDTGASSYCLQPPAGSVLSGT WPHPRPGPPPLMAPWPWGPPASQSSPWPRATAFWTSTSDSEPPASGDLCSEPSTPASPPP SEEGARTGPAEPVSQAEATSTGEPPPGSGGLALPWDPHSLEMVLIGCHGSGTVQWTQEEG TGV |
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| External Links | ||||||||||||||||||||||||||||||||||||||||||
| GenBank ID Protein | Not Available | |||||||||||||||||||||||||||||||||||||||||
| UniProtKB/Swiss-Prot ID | Q9ULD8 | |||||||||||||||||||||||||||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | KCNH3_HUMAN | |||||||||||||||||||||||||||||||||||||||||
| PDB IDs | Not Available | |||||||||||||||||||||||||||||||||||||||||
| GenBank Gene ID | AB022696 | |||||||||||||||||||||||||||||||||||||||||
| GeneCard ID | KCNH3 | |||||||||||||||||||||||||||||||||||||||||
| GenAtlas ID | KCNH3 | |||||||||||||||||||||||||||||||||||||||||
| HGNC ID | HGNC:6252 | |||||||||||||||||||||||||||||||||||||||||
| References | ||||||||||||||||||||||||||||||||||||||||||
| General References | Not Available | |||||||||||||||||||||||||||||||||||||||||