| Identification |
|---|
| HMDB Protein ID
| CDBP03353 |
| Secondary Accession Numbers
| Not Available |
| Name
| cAMP-dependent protein kinase type II-beta regulatory subunit |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| PRKAR2B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cAMP-dependent protein kinase regulator activity |
| Specific Function
| Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase |
| GO Classification
|
| Component |
| macromolecular complex |
| protein complex |
| camp-dependent protein kinase complex |
| Function |
| enzyme regulator activity |
| kinase regulator activity |
| protein kinase regulator activity |
| camp-dependent protein kinase regulator activity |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of cellular process |
| signal transduction |
| regulation of cellular metabolic process |
| regulation of cellular protein metabolic process |
| regulation of protein modification process |
| regulation of protein amino acid phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q22 |
| SNPs
| PRKAR2B |
| Gene Sequence
|
>1257 bp
ATGAGCATCGAGATCCCGGCGGGACTGACGGAGCTGCTGCAGGGCTTCACGGTGGAGGTG
CTGAGGCACCAGCCCGCGGACCTGCTGGAGTTCGCTCTGCAGCACTTCACCCGCCTGCAG
CAGGAGAACGAGCGCAAAGGCACCGCGCGCTTCGGCCATGAGGGCAGGACCTGGGGGGAC
CTGGGCGCCGCTGCCGGGGGCGGCACCCCCAGCAAGGGGGTCAACTTCGCCGAGGAGCCC
ATGCAGTCCGACTCCGAGGACGGGGAGGAGGAGGAGGCGGCGCCCGCGGACGCAGGGGCG
TTCAATGCTCCAGTAATAAACCGATTCACAAGGCGTGCCTCAGTATGTGCAGAAGCTTAT
AATCCTGATGAAGAAGAAGATGATGCAGAGTCCAGGATTATACATCCAAAAACTGATGAT
CAAAGAAATAGGTTGCAAGAGGCTTGCAAAGACATCCTGCTGTTTAAGAATCTGGATCCG
GAGCAGATGTCTCAAGTATTAGATGCCATGTTTGAAAAACTGGTCAAAGATGGGGAGCAT
GTAATTGATCAAGGTGACGATGGTGACAACTTTTATGTAATTGATAGAGGCACATTTGAT
ATTTATGTGAAATGTGATGGTGTTGGAAGATGTGTTGGTAACTATGATAATCGTGGGAGT
TTCGGCGAACTGGCCTTAATGTACAATACACCCAGAGCAGCTACAATCACTGCTACCTCT
CCTGGTGCTCTGTGGGGTTTGGACAGGGTAACCTTCAGGAGAATAATTGTGAAAAACAAT
GCCAAAAAGAGAAAAATGTATGAAAGCTTTATTGAGTCACTGCCATTCCTTAAATCTTTG
GAGTTTTCTGAACGCCTGAAAGTAGTAGATGTGATAGGCACCAAAGTATACAACGATGGA
GAACAAATCATTGCTCAGGGAGATTCGGCTGATTCTTTTTTCATTGTAGAATCTGGAGAA
GTGAAAATTACTATGAAAAGAAAGGGTAAATCAGAAGTGGAAGAGAATGGTGCAGTAGAA
ATCGCTCGATGCTCGCGGGGACAGTACTTTGGAGAGCTTGCCCTGGTAACTAACAAACCT
CGAGCAGCTTCTGCCCACGCCATTGGGACTGTCAAATGTTTAGCAATGGATGTGCAAGCA
TTTGAAAGGCTTCTGGGACCTTGCATGGAAATTATGAAAAGGAACATCGCTACCTATGAA
GAACAGTTAGTTGCCCTGTTTGGAACGAACATGGATATTGTTGAACCCACTGCATGA
|
| Protein Properties |
|---|
| Number of Residues
| 418 |
| Molecular Weight
| 46301.7 |
| Theoretical pI
| 4.55 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>cAMP-dependent protein kinase type II-beta regulatory subunit
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGD
LGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAY
NPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEH
VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATS
PGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDG
EQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKP
RAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
|
| External Links |
|---|
| GenBank ID Protein
| 158256318 |
| UniProtKB/Swiss-Prot ID
| P31323 |
| UniProtKB/Swiss-Prot Entry Name
| KAP3_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK291441 |
| GeneCard ID
| PRKAR2B |
| GenAtlas ID
| PRKAR2B |
| HGNC ID
| HGNC:9392 |
| References |
|---|
| General References
| Not Available |