| Identification |
|---|
| HMDB Protein ID
| CDBP03331 |
| Secondary Accession Numbers
| Not Available |
| Name
| Basic leucine zipper transcriptional factor ATF-like |
| Description
| Not Available |
| Synonyms
|
- B-ATF
- B-cell-activating transcription factor
- SF-HT-activated gene 2 protein
- SFA-2
|
| Gene Name
| BATF |
| Protein Type
| Transcription Factor |
| Biological Properties |
|---|
| General Function
| Involved in sequence-specific DNA binding transcription factor activity |
| Specific Function
| Functions as a negative regulator of AP-1 mediated transcription by binding to Jun proteins. Jun/B-ATF heterodimers bind DNA preferentially at the 12-O-tetradecanoylphorbol-13- acetate response element (TRE) (consensus:5'-TGA[CG]TCA-3') and weaker at the cAMP-responsive region (CRE) (consensus:5'- GTGACGT[AC][AG]-3'), but are transcriptionally inert |
| GO Classification
|
| Component |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| nucleus |
| Function |
| sequence-specific dna binding |
| sequence-specific dna binding transcription factor activity |
| binding |
| protein binding |
| nucleic acid binding |
| dna binding |
| protein dimerization activity |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of macromolecule metabolic process |
| regulation of gene expression |
| regulation of transcription |
| regulation of transcription, dna-dependent |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q24.3 |
| SNPs
| BATF |
| Gene Sequence
|
>378 bp
ATGCCTCACAGCTCCGACAGCAGTGACTCCAGCTTCAGCCGCTCTCCTCCCCCTGGCAAA
CAGGACTCATCTGATGATGTGAGAAGAGTTCAGAGGAGGGAGAAAAATCGTATTGCCGCC
CAGAAGAGCCGACAGAGGCAGACACAGAAGGCCGACACCCTGCACCTGGAGAGCGAAGAC
CTGGAGAAACAGAACGCGGCTCTACGCAAGGAGATCAAGCAGCTCACAGAGGAACTGAAG
TACTTCACGTCGGTGCTGAACAGCCACGAGCCCCTGTGCTCGGTGCTGGCCGCCAGCACG
CCCTCGCCCCCCGAGGTGGTGTACAGCGCCCACGCATTCCACCAACCTCATGTCAGCTCC
CCGCGCTTCCAGCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 125 |
| Molecular Weight
| 14119.5 |
| Theoretical pI
| 9.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Basic leucine zipper transcriptional factor ATF-like
MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESED
LEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSS
PRFQP
|
| External Links |
|---|
| GenBank ID Protein
| 5764706 |
| UniProtKB/Swiss-Prot ID
| Q16520 |
| UniProtKB/Swiss-Prot Entry Name
| BATF_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC007182 |
| GeneCard ID
| BATF |
| GenAtlas ID
| BATF |
| HGNC ID
| HGNC:958 |
| References |
|---|
| General References
| Not Available |