Identification |
HMDB Protein ID
| CDBP03330 |
Secondary Accession Numbers
| Not Available |
Name
| Cyclic AMP-dependent transcription factor ATF-7 |
Description
| Not Available |
Synonyms
|
- Activating transcription factor 7
- Transcription factor ATF-A
- cAMP-dependent transcription factor ATF-7
|
Gene Name
| ATF7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in sequence-specific DNA binding transcription factor activity |
Specific Function
| Isoform 4/ATF-A0 acts as a dominant repressor of the E- selectin/NF-ELAM1/delta-A promoter |
GO Classification
|
Component |
cell part |
intracellular |
Function |
dna binding |
protein dimerization activity |
sequence-specific dna binding |
sequence-specific dna binding transcription factor activity |
ion binding |
cation binding |
metal ion binding |
binding |
transition metal ion binding |
zinc ion binding |
protein binding |
nucleic acid binding |
Process |
biological regulation |
regulation of biological process |
regulation of metabolic process |
regulation of macromolecule metabolic process |
regulation of gene expression |
regulation of transcription |
regulation of transcription, dna-dependent |
|
Cellular Location
|
- Nucleus
- Nucleus
- nucleoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12q13 |
SNPs
| ATF7 |
Gene Sequence
|
>1485 bp
ATGGGAGACGACAGACCGTTTGTGTGCAATGCCCCGGGCTGTGGACAGAGATTTACAAAC
GAGGACCACCTGGCAGTTCATAAACACAAGCATGAGATGACATTGAAATTTGGCCCAGCC
CGAACTGACTCAGTCATCATTGCAGATCAAACGCCTACTCCAACTAGATTCCTGAAGAAC
TGTGAGGAGGTGGGACTCTTCAATGAACTAGCTAGCTCCTTTGAACATGAATTCAAGAAA
GCTGCAGATGAGGATGAGAAAAAGGCAAGAAGCAGGACTGTTGCCAAAAAACTGGTGGCT
GCTGCTGGGCCCCTTGACATGTCTCTGCCTTCCACACCAGACATCAAAATCAAAGAAGAA
GAGCCAGTGGAGGTAGACTCATCCCCACCTGATAGCCCTGCCTCTAGTCCCTGTTCCCCA
CCACTGAAGGAGAAGGAGGTTACCCCAAAGCCTGTTCTGATCTCTACCCCCACACCCACC
ATTGTACGTCCTGGCTCCCTGCCTCTCCACTTGGGCTATGATCCACTTCATCCAACCCTT
CCCTCCCCAACCTCTGTCATCACACAGGCTCCACCATCCAACAGGCAAATGGGGTCTCCC
ACTGGCTCCCTCCCTCTTGTCATGCATCTTGCTAATGGACAGACCATGCCTGTGTTGCCA
GGGCCTCCAGTACAGATGCCGTCTGTTATATCGCTGGCCAGACCTGTGTCCATGGTGCCC
AACATTCCTGGTATCCCTGGCCCACCAGTTAACAGTAGTGGCTCCATTTCTCCCTCTGGC
CACCCTATACCATCAGAAGCCAAGATGAGACTGAAAGCCACCCTAACTCACCAAGTCTCC
TCAATCAATGGTGGTTGTGGAATGGTGGTGGGTACTGCCAGCACCATGGTGACAGCCCGC
CCAGAGCAGAGCCAGATTCTCATCCAGCACCCTGATGCCCCATCCCCTGCCCAGCCACAG
GTCTCACCAGCTCAGCCCACCCCTAGTACTGGGGGGCGACGGCGGCGCACAGTAGATGAA
GATCCAGATGAGCGACGGCAGCGCTTTCTGGAGCGCAACCGGGCTGCAGCCTCCCGCTGC
CGCCAAAAGCGAAAGCTGTGGGTGTCCTCCCTAGAGAAGAAGGCCGAAGAACTCACTTCT
CAGAACATTCAGCTGAGTAATGAAGTCACATTACTACGCAATGAGGTGGCCCAGTTGAAA
CAGCTACTGTTAGCTCATAAAGACTGCCCAGTCACTGCACTACAGAAAAAGACTCAAGGC
TATTTAGAAAGCCCCAAGGAAAGCTCAGAGCCAACGGGTTCTCCAGCCCCTGTGATTCAG
CACAGCTCAGCAACAGCCCCTAGCAATGGCCTCAGTGTTCGCTCTGCAGCTGAAGCTGTG
GCCACCTCGGTCCTCACTCAGATGGCCAGCCAAAGGACAGAACTGAGCATGCCGATACAA
TCGCATGTAATCATGACCCCACAGTCCCAGTCTGCGGGCAGATGA
|
Protein Properties |
Number of Residues
| 494 |
Molecular Weight
| 52966.9 |
Theoretical pI
| 8.89 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Cyclic AMP-dependent transcription factor ATF-7
MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKN
CEEVGLFNELASSFEHEFKKAADEDEKKARSRTVAKKLVAAAGPLDMSLPSTPDIKIKEE
EPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTL
PSPTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVP
NIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTAR
PEQSQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRC
RQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQG
YLESPKESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQ
SHVIMTPQSQSAGR
|
External Links |
GenBank ID Protein
| 194385140 |
UniProtKB/Swiss-Prot ID
| P17544 |
UniProtKB/Swiss-Prot Entry Name
| ATF7_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK298853 |
GeneCard ID
| ATF7 |
GenAtlas ID
| ATF7 |
HGNC ID
| HGNC:792 |
References |
General References
| Not Available |