Identification
HMDB Protein ID CDBP03319
Secondary Accession Numbers Not Available
Name ADM2
Description Not Available
Synonyms
  1. AM2
  2. Adrenomedullin-2
  3. IMDL
  4. IMDS
  5. Intermedin
  6. Intermedin-long
  7. Intermedin-short
Gene Name ADM2
Protein Type Receptor
Biological Properties
General Function Involved in hormone activity
Specific Function IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway
GO Classification
Component
extracellular region
Function
hormone activity
binding
protein binding
receptor binding
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q13.33
SNPs ADM2
Gene Sequence
>447 bp
ATGGCCCGGATCCCGACGGCCGCCCTGGGTTGCATCAGCCTCCTCTGCCTGCAGCTCCCT
GGCTCGCTGTCCCGCAGCCTGGGCGGGGACCCGCGACCCGTCAAACCCAGGGAGCCCCCA
GCCCGGAGCCCTTCCAGCAGCCTGCAGCCCAGGCACCCCGCACCCCGACCTGTGGTCTGG
AAGCTTCACCGGGCCCTCCAGGCACAGAGGGGTGCCGGCCTGGCCCCTGTTATGGGTCAG
CCTCTCCGGGATGGTGGCCGCCAACACTCGGGCCCCCGAAGACACTCGGGCCCCCGCAGG
ACCCAAGCCCAGCTCCTGCGAGTGGGCTGTGTGCTGGGCACCTGCCAGGTGCAGAATCTC
AGCCACCGCCTGTGGCAACTCATGGGACCGGCCGGCCGGCAGGACTCAGCTCCTGTGGAC
CCCAGCAGCCCCCACAGCTATGGCTGA
Protein Properties
Number of Residues 148
Molecular Weight 15865.2
Theoretical pI 12.31
Pfam Domain Function
Signals
  • ["1-24"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>ADM2
MARIPTAALGCISLLCLQLPGSLSRSLGGDPRPVKPREPPARSPSSSLQPRHPAPRPVVW
KLHRALQAQRGAGLAPVMGQPLRDGGRQHSGPRRHSGPRRTQAQLLRVGCVLGTCQVQNL
SHRLWQLMGPAGRQDSAPVDPSSPHSYG
GenBank ID Protein 41016726
UniProtKB/Swiss-Prot ID Q7Z4H4
UniProtKB/Swiss-Prot Entry Name ADM2_HUMAN
PDB IDs Not Available
GenBank Gene ID AB121034
GeneCard ID ADM2
GenAtlas ID ADM2
HGNC ID HGNC:28898
References
General References Not Available