Identification |
HMDB Protein ID
| CDBP03319 |
Secondary Accession Numbers
| Not Available |
Name
| ADM2 |
Description
| Not Available |
Synonyms
|
- AM2
- Adrenomedullin-2
- IMDL
- IMDS
- Intermedin
- Intermedin-long
- Intermedin-short
|
Gene Name
| ADM2 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in hormone activity |
Specific Function
| IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway |
GO Classification
|
Component |
extracellular region |
Function |
hormone activity |
binding |
protein binding |
receptor binding |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 22q13.33 |
SNPs
| ADM2 |
Gene Sequence
|
>447 bp
ATGGCCCGGATCCCGACGGCCGCCCTGGGTTGCATCAGCCTCCTCTGCCTGCAGCTCCCT
GGCTCGCTGTCCCGCAGCCTGGGCGGGGACCCGCGACCCGTCAAACCCAGGGAGCCCCCA
GCCCGGAGCCCTTCCAGCAGCCTGCAGCCCAGGCACCCCGCACCCCGACCTGTGGTCTGG
AAGCTTCACCGGGCCCTCCAGGCACAGAGGGGTGCCGGCCTGGCCCCTGTTATGGGTCAG
CCTCTCCGGGATGGTGGCCGCCAACACTCGGGCCCCCGAAGACACTCGGGCCCCCGCAGG
ACCCAAGCCCAGCTCCTGCGAGTGGGCTGTGTGCTGGGCACCTGCCAGGTGCAGAATCTC
AGCCACCGCCTGTGGCAACTCATGGGACCGGCCGGCCGGCAGGACTCAGCTCCTGTGGAC
CCCAGCAGCCCCCACAGCTATGGCTGA
|
Protein Properties |
Number of Residues
| 148 |
Molecular Weight
| 15865.2 |
Theoretical pI
| 12.31 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>ADM2
MARIPTAALGCISLLCLQLPGSLSRSLGGDPRPVKPREPPARSPSSSLQPRHPAPRPVVW
KLHRALQAQRGAGLAPVMGQPLRDGGRQHSGPRRHSGPRRTQAQLLRVGCVLGTCQVQNL
SHRLWQLMGPAGRQDSAPVDPSSPHSYG
|
External Links |
GenBank ID Protein
| 41016726 |
UniProtKB/Swiss-Prot ID
| Q7Z4H4 |
UniProtKB/Swiss-Prot Entry Name
| ADM2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AB121034 |
GeneCard ID
| ADM2 |
GenAtlas ID
| ADM2 |
HGNC ID
| HGNC:28898 |
References |
General References
| Not Available |