| Identification |
|---|
| HMDB Protein ID
| CDBP03316 |
| Secondary Accession Numbers
| Not Available |
| Name
| Chemokine XC receptor 1 |
| Description
| Not Available |
| Synonyms
|
- G-protein coupled receptor 5
- Lymphotactin receptor
- XC chemokine receptor 1
|
| Gene Name
| XCR1 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level |
| GO Classification
|
| Component |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| peptide receptor activity |
| peptide receptor activity, g-protein coupled |
| receptor activity |
| g-protein chemoattractant receptor activity |
| chemokine receptor activity |
| molecular transducer activity |
| signal transducer activity |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p21.3-p21.1|3p21.3 |
| SNPs
| XCR1 |
| Gene Sequence
|
>1002 bp
ATGGAGTCCTCAGGCAACCCAGAGAGCACCACCTTTTTTTACTATGACCTTCAGAGCCAG
CCGTGTGAGAACCAGGCCTGGGTCTTTGCTACCCTCGCCACCACTGTCCTATACTGCCTG
GTGTTTCTCCTCAGCCTAGTGGGCAACAGCCTGGTCCTGTGGGTCCTGGTGAAGTATGAG
AGCCTGGAGTCCCTCACCAACATCTTCATCCTCAACCTGTGCCTCTCAGACCTGGTGTTC
GCCTGCTTGTTGCCTGTGTGGATCTCCCCATACCACTGGGGCTGGGTGCTGGGAGACTTC
CTCTGCAAACTCCTCAATATGATCTTCTCCATCAGCCTCTACAGCAGCATCTTCTTCCTG
ACCATCATGACCATCCACCGCTACCTGTCGGTAGTGAGCCCCCTCTCCACCCTGCGCGTC
CCCACCCTCCGCTGCCGGGTGCTGGTGACCATGGCTGTGTGGGTAGCCAGCATCCTGTCC
TCCATCCTCGACACCATCTTCCACAAGGTGCTTTCTTCGGGCTGTGATTATTCCGAACTC
ACGTGGTACCTCACCTCCGTCTACCAGCACAACCTCTTCTTCCTGCTGTCCCTGGGGATT
ATCCTGTTCTGCTACGTGGAGATCCTCAGGACCCTGTTCCGCTCACGCTCCAAGCGGCGC
CACCGCACGGTCAAGCTCATCTTCGCCATCGTGGTGGCCTACTTCCTCAGCTGGGGTCCC
TACAACTTCACCCTGTTTCTGCAGACGCTGTTTCGGACCCAGATCATCCGGAGCTGCGAG
GCCAAACAGCAGCTAGAATACGCCCTGCTCATCTGCCGCAACCTCGCCTTCTCCCACTGC
TGCTTTAACCCGGTGCTCTATGTCTTCGTGGGGGTCAAGTTCCGCACACACCTGAAACAT
GTTCTCCGGCAGTTCTGGTTCTGCCGGCTGCAGGCACCCAGCCCAGCCTCGATCCCCCAC
TCCCCTGGTGCCTTCGCCTATGAGGGCGCCTCCTTCTACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 333 |
| Molecular Weight
| 38507.0 |
| Theoretical pI
| 8.68 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["32-59", "70-89", "104-125", "143-167", "191-209", "226-250", "268-291"]
|
| Protein Sequence
|
>Chemokine XC receptor 1
MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVKYE
SLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFFL
TIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDYSEL
TWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGP
YNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVKFRTHLKH
VLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY
|
| External Links |
|---|
| GenBank ID Protein
| 30526192 |
| UniProtKB/Swiss-Prot ID
| P46094 |
| UniProtKB/Swiss-Prot Entry Name
| XCR1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY275469 |
| GeneCard ID
| XCR1 |
| GenAtlas ID
| XCR1 |
| HGNC ID
| HGNC:1625 |
| References |
|---|
| General References
| Not Available |