Identification
HMDB Protein ID CDBP03302
Secondary Accession Numbers Not Available
Name Trypsin-3
Description Not Available
Synonyms
  1. Brain trypsinogen
  2. Mesotrypsinogen
  3. Serine protease 3
  4. Serine protease 4
  5. Trypsin III
  6. Trypsin IV
Gene Name PRSS3
Protein Type Enzyme
Biological Properties
General Function Involved in serine-type endopeptidase activity
Specific Function Preferential cleavage:Arg-|-Xaa, Lys-|-Xaa
GO Classification
Function
peptidase activity, acting on l-amino acid peptides
endopeptidase activity
serine-type endopeptidase activity
catalytic activity
hydrolase activity
peptidase activity
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:9
Locus 9p11.2
SNPs PRSS3
Gene Sequence
>915 bp
ATGTGCGGACCTGACGACAGATGCCCCGCACGCTGGCCGGGACCGGGAAGGGCGGTCAAG
TGTGGAAAGGGTCTGGCGGCTGCCAGGCCTGGCAGAGTGGAGCGGGGCGGGGCGCAGCGG
GGCGGGGCGGGCCTGGAGCTGCACCCGCTTCTGGGTGGACGCACTTGGCGAGCGGCGCGG
GATGCAGACGGCTGCGAGGCGCTGGGCACAGTTGCTGTCCCCTTTGACGATGATGACAAG
ATTGTTGGGGGCTACACCTGTGAGGAGAATTCTCTCCCCTACCAGGTGTCCCTGAATTCT
GGCTCCCACTTCTGCGGTGGCTCCCTCATCAGCGAACAGTGGGTGGTATCAGCAGCTCAC
TGCTACAAGACCCGCATCCAGGTGAGACTGGGAGAGCACAACATCAAAGTCCTGGAGGGG
AATGAGCAGTTCATCAATGCGGCCAAGATCATCCGCCACCCTAAATACAACAGGGACACT
CTGGACAATGACATCATGCTGATCAAACTCTCCTCACCTGCCGTCATCAATGCCCGCGTG
TCCACCATCTCTCTGCCCACCACCCCTCCAGCTGCTGGCACTGAGTGCCTCATCTCCGGC
TGGGGCAACACTCTGAGCTTTGGTGCTGACTACCCAGACGAGCTGAAGTGCCTGGATGCT
CCGGTGCTGACCCAGGCTGAGTGTAAAGCCTCCTACCCTGGAAAGATTACCAACAGCATG
TTCTGTGTGGGCTTCCTTGAGGGAGGCAAGGATTCCTGCCAGCGTGACTCTGGTGGCCCT
GTGGTCTGCAACGGACAGCTCCAAGGAGTTGTCTCCTGGGGCCATGGCTGTGCCTGGAAG
AACAGGCCTGGAGTCTACACCAAGGTCTACAACTATGTGGACTGGATTAAGGACACCATC
GCTGCCAACAGCTAA
Protein Properties
Number of Residues 304
Molecular Weight 32528.6
Theoretical pI 7.54
Pfam Domain Function
Signals
  • ["1-"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Trypsin-3
MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAAR
DADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAH
CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV
STISLPTTPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM
FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI
AANS
GenBank ID Protein 57162227
UniProtKB/Swiss-Prot ID P35030
UniProtKB/Swiss-Prot Entry Name TRY3_HUMAN
PDB IDs
GenBank Gene ID AL139113
GeneCard ID PRSS3
GenAtlas ID PRSS3
HGNC ID HGNC:9486
References
General References Not Available