Identification
HMDB Protein ID CDBP03301
Secondary Accession Numbers Not Available
Name Trypsin-2
Description Not Available
Synonyms
  1. Anionic trypsinogen
  2. Serine protease 2
  3. Trypsin II
Gene Name PRSS2
Protein Type Enzyme
Biological Properties
General Function Involved in serine-type endopeptidase activity
Specific Function Preferential cleavage:Arg-|-Xaa, Lys-|-Xaa
GO Classification
Function
endopeptidase activity
serine-type endopeptidase activity
catalytic activity
hydrolase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis
Cellular Location
  1. Secreted
  2. extracellular space
Pathways
Gene Properties
Chromosome Location Chromosome:7
Locus 7q34
SNPs PRSS2
Gene Sequence
>744 bp
ATGAATCTACTCCTGATCCTTACCTTTGTTGCAGCTGCTGTTGCTGCCCCCTTTGATGAT
GATGACAAGATCGTTGGGGGCTACATCTGTGAGGAGAATTCTGTCCCCTACCAGGTGTCC
TTGAATTCTGGCTACCACTTCTGCGGTGGCTCCCTCATCAGCGAACAGTGGGTGGTGTCA
GCAGGTCACTGCTACAAGTCCCGCATCCAGGTGAGACTGGGAGAGCACAACATCGAAGTC
CTGGAGGGGAATGAACAGTTCATCAATGCGGCCAAGATCATCCGCCACCCCAAATACAAC
AGCCGGACTCTGGACAATGACATCCTGCTGATCAAGCTCTCCTCACCTGCCGTCATCAAT
TCCCGCGTGTCCGCCATCTCTCTGCCCACTGCCCCTCCAGCTGCTGGCACCGAGTCCCTC
ATCTCCGGCTGGGGCAACACTCTGAGTTCTGGTGCCGACTACCCAGACGAGCTGCAGTGC
CTGGATGCTCCTGTGCTGAGCCAGGCTGAGTGTGAAGCCTCCTACCCTGGAAAGATTACC
AACAACATGTTCTGTGTGGGCTTCCTCGAGGGAGGCAAGGATTCCTGCCAGGGTGATTCT
GGTGGCCCTGTGGTCTCCAATGGAGAGCTCCAAGGAATTGTCTCCTGGGGCTATGGCTGT
GCCCAGAAGAACAGGCCTGGAGTCTACACCAAGGTCTACAACTATGTGGACTGGATTAAG
GACACCATAGCTGCCAACAGCTAA
Protein Properties
Number of Residues 247
Molecular Weight 26487.6
Theoretical pI 4.54
Pfam Domain Function
Signals
  • ["1-15"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Trypsin-2
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
DTIAANS
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P07478
UniProtKB/Swiss-Prot Entry Name TRY2_HUMAN
PDB IDs
GenBank Gene ID M27602
GeneCard ID PRSS2
GenAtlas ID PRSS2
HGNC ID HGNC:9483
References
General References Not Available