Identification |
HMDB Protein ID
| CDBP03301 |
Secondary Accession Numbers
| Not Available |
Name
| Trypsin-2 |
Description
| Not Available |
Synonyms
|
- Anionic trypsinogen
- Serine protease 2
- Trypsin II
|
Gene Name
| PRSS2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in serine-type endopeptidase activity |
Specific Function
| Preferential cleavage:Arg-|-Xaa, Lys-|-Xaa |
GO Classification
|
Function |
endopeptidase activity |
serine-type endopeptidase activity |
catalytic activity |
hydrolase activity |
peptidase activity |
peptidase activity, acting on l-amino acid peptides |
Process |
metabolic process |
macromolecule metabolic process |
protein metabolic process |
proteolysis |
|
Cellular Location
|
- Secreted
- extracellular space
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:7 |
Locus
| 7q34 |
SNPs
| PRSS2 |
Gene Sequence
|
>744 bp
ATGAATCTACTCCTGATCCTTACCTTTGTTGCAGCTGCTGTTGCTGCCCCCTTTGATGAT
GATGACAAGATCGTTGGGGGCTACATCTGTGAGGAGAATTCTGTCCCCTACCAGGTGTCC
TTGAATTCTGGCTACCACTTCTGCGGTGGCTCCCTCATCAGCGAACAGTGGGTGGTGTCA
GCAGGTCACTGCTACAAGTCCCGCATCCAGGTGAGACTGGGAGAGCACAACATCGAAGTC
CTGGAGGGGAATGAACAGTTCATCAATGCGGCCAAGATCATCCGCCACCCCAAATACAAC
AGCCGGACTCTGGACAATGACATCCTGCTGATCAAGCTCTCCTCACCTGCCGTCATCAAT
TCCCGCGTGTCCGCCATCTCTCTGCCCACTGCCCCTCCAGCTGCTGGCACCGAGTCCCTC
ATCTCCGGCTGGGGCAACACTCTGAGTTCTGGTGCCGACTACCCAGACGAGCTGCAGTGC
CTGGATGCTCCTGTGCTGAGCCAGGCTGAGTGTGAAGCCTCCTACCCTGGAAAGATTACC
AACAACATGTTCTGTGTGGGCTTCCTCGAGGGAGGCAAGGATTCCTGCCAGGGTGATTCT
GGTGGCCCTGTGGTCTCCAATGGAGAGCTCCAAGGAATTGTCTCCTGGGGCTATGGCTGT
GCCCAGAAGAACAGGCCTGGAGTCTACACCAAGGTCTACAACTATGTGGACTGGATTAAG
GACACCATAGCTGCCAACAGCTAA
|
Protein Properties |
Number of Residues
| 247 |
Molecular Weight
| 26487.6 |
Theoretical pI
| 4.54 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Trypsin-2
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
DTIAANS
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| P07478 |
UniProtKB/Swiss-Prot Entry Name
| TRY2_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| M27602 |
GeneCard ID
| PRSS2 |
GenAtlas ID
| PRSS2 |
HGNC ID
| HGNC:9483 |
References |
General References
| Not Available |