| Identification |
|---|
| HMDB Protein ID
| CDBP03280 |
| Secondary Accession Numbers
| Not Available |
| Name
| Prosalusin |
| Description
| Not Available |
| Synonyms
|
- Salusin-alpha
- Salusin-beta
- Torsin family 2 member A
- Torsin-2A
|
| Gene Name
| TOR2A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Salusins -alpha and -beta may be endocrine and/or paracrine factors able to increase intracellular calcium concentrations and induce cell mitogenesis. Salusins may also be potent hypotensive peptides |
| GO Classification
|
| Component |
| endoplasmic reticulum |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| Function |
| adenyl ribonucleotide binding |
| atp binding |
| binding |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| Process |
| metabolic process |
| macromolecule metabolic process |
| 'de novo' protein folding |
| 'de novo' posttranslational protein folding |
| chaperone mediated protein folding requiring cofactor |
| cellular protein metabolic process |
| protein folding |
| protein metabolic process |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q34.11 |
| SNPs
| TOR2A |
| Gene Sequence
|
>729 bp
ATGGCGGCTGCGACGCGCGGCTGCCGGCCCTGGGGCTCGCTCCTCGGGCTGCTCGGGCTG
GTCTCGGCCGCGGCCGCCGCCTGGGACCTGGCTTCCCTGCGCTGCACCTTGGGCGCCTTT
TGCGAATGCGACTTCCGGCCCGACTTGCCGGGTCTGGAGTGTGACCTGGCTCAGCACCTG
GCCGGCCAGCATCTGGCCAAGGCGCTGGTGGTGAAGGCGCTGAAGGCCTTTGTGCGGGAC
CCAGCCCCCACCAAGCCGCTGGTCCTCTCCCTGCACGGCTGGACCGGCACCGGCAAATCC
TATGTCAGCTCCCTGCTGGCGCACTACCTCTTCCAGGGCGGCCTCCGCAGCCCCCGCGTG
CACCACTTTTCTCCCGTCCTCCACTTCCCCCACCCCAGCCACATCGAGCGCTACAAGAAG
GATCTGAAGAGCTGGGTCCAAGGGAACCTCACTGCCTGTGGCCGCTCCCTCTTCCTCTTC
GATGAGATGGACAAGATGCCCCCAGGCCTGATGGAAGTCCTGCGGCCTTTCCTGGGCTCC
TCCTGGGTGGTATACGGGACCAATTACCGCAAAGCCATCTTCATCTTCATCAGATGGCTT
CTCAAACTCGGGCATCATGGAAGAGCGCCTCCTAGACGCAGTGGTGCCCTTCCTCCCGCT
CCAGCGGCACCACGTCCGGCACTGCGTGCTCAACGAGCTGGCCCAGCTGGGCCTGGAGCC
AAGGGATGA
|
| Protein Properties |
|---|
| Number of Residues
| 242 |
| Molecular Weight
| 26261.5 |
| Theoretical pI
| 10.75 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Prosalusin
MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHL
AGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRV
HHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGS
SWVVYGTNYRKAIFIFIRWLLKLGHHGRAPPRRSGALPPAPAAPRPALRAQRAGPAGPGA
KG
|
| External Links |
|---|
| GenBank ID Protein
| 22761716 |
| UniProtKB/Swiss-Prot ID
| Q8N2E6 |
| UniProtKB/Swiss-Prot Entry Name
| TOR2X_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK075520 |
| GeneCard ID
| TOR2A |
| GenAtlas ID
| TOR2A |
| HGNC ID
| HGNC:11996 |
| References |
|---|
| General References
| Not Available |