Identification |
HMDB Protein ID
| CDBP03265 |
Secondary Accession Numbers
| Not Available |
Name
| Tescalcin |
Description
| Not Available |
Synonyms
|
- CHP3
- Calcineurin B homologous protein 3
- TSC
|
Gene Name
| TESC |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in calcium ion binding |
Specific Function
| Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation |
GO Classification
|
Function |
ion binding |
cation binding |
metal ion binding |
binding |
calcium ion binding |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12q24.22 |
SNPs
| TESC |
Gene Sequence
|
>645 bp
ATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTC
TCATCGGATCAGATCGAGCAGCTCCATCGGAGATTTAAGCAGCTGAGTGGAGATCAGCCT
ACCATTCGCAAGGAGAACTTCAACAATGTCCCGGACCTGGAGCTCAACCCCATCCGATCC
AAAATTGTTCGTGCCTTCTTCGACAACAGGAACCTGCGCAAGGGACCCAGTGGCCTGGCT
GATGAGATCAATTTCGAGGACTTCCTGACCATCATGTCCTACTTCCGGCCCATCGACACC
ACCATGGACGAGGAACAGGTGGAGCTGTCCCGGAAGGAGAAGCTGAGATTTCTGTTCCAC
ATGTACGACTCGGACAGCGACGGCCGCATCACTCTGGAAGAATATCGAAATGTGGTCGAG
GAGCTGCTGTCGGGAAACCCTCACATCGAGAAGGAGTCCGCTCGCTCCATCGCCGACGGG
GCCATGATGGAGGCGGCCAGCGTGTGCATGGGGCAGATGGAGCCTGATCAGGTGTACGAG
GGGATCACCTTCGAGGACTTCCTGAAGATCTGGCAGGGGATCGACATTGAGACCAAGATG
CACGTCCGCTTCCTTAACATGGAAACCATGGCCCTCTGCCACTGA
|
Protein Properties |
Number of Residues
| 214 |
Molecular Weight
| 24749.7 |
Theoretical pI
| 4.57 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Tescalcin
MGAAHSASEEVRELEGKTGFSSDQIEQLHRRFKQLSGDQPTIRKENFNNVPDLELNPIRS
KIVRAFFDNRNLRKGPSGLADEINFEDFLTIMSYFRPIDTTMDEEQVELSRKEKLRFLFH
MYDSDSDGRITLEEYRNVVEELLSGNPHIEKESARSIADGAMMEAASVCMGQMEPDQVYE
GITFEDFLKIWQGIDIETKMHVRFLNMETMALCH
|
External Links |
GenBank ID Protein
| 269996002 |
UniProtKB/Swiss-Prot ID
| Q96BS2 |
UniProtKB/Swiss-Prot Entry Name
| TESC_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_017899.3 |
GeneCard ID
| TESC |
GenAtlas ID
| TESC |
HGNC ID
| HGNC:26065 |
References |
General References
| Not Available |