| Identification |
|---|
| HMDB Protein ID
| CDBP03257 |
| Secondary Accession Numbers
| Not Available |
| Name
| Taste receptor type 2 member 7 |
| Description
| Not Available |
| Synonyms
|
- T2R7
- TRB4
- Taste receptor family B member 4
|
| Gene Name
| TAS2R7 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor activity |
| Specific Function
| Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 |
| GO Classification
|
| Component |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| cell part |
| Function |
| receptor activity |
| transmembrane receptor activity |
| molecular transducer activity |
| signal transducer activity |
| g-protein coupled receptor activity |
| Process |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
| multicellular organismal process |
| system process |
| neurological system process |
| sensory perception |
| sensory perception of chemical stimulus |
| sensory perception of taste |
| signaling |
| signaling pathway |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12p13 |
| SNPs
| TAS2R7 |
| Gene Sequence
|
>957 bp
ATGGCAGATAAAGTGCAGACTACTTTATTGTTCTTAGCAGTTGGAGAGTTTTCAGTGGGG
ATCTTAGGGAATGCATTCATTGGATTGGTAAACTGCATGGACTGGGTCAAGAAGAGGAAA
ATTGCCTCCATTGATTTAATCCTCACAAGTCTGGCCATATCCAGAATTTGTCTATTGTGC
GTAATACTATTAGATTGTTTTATATTGGTGCTATATCCAGATGTCTATGCCACTGGTAAA
GAAATGAGAATCATTGACTTCTTCTGGACACTAACCAATCATTTAAGTATCTGGTTTGCA
ACCTGCCTCAGCATTTACTATTTCTTCAAGATAGGTAATTTCTTTCACCCACTTTTCCTC
TGGATGAAGTGGAGAATTGACAGGGTGATTTCCTGGATTCTACTGGGGTGCGTGGTTCTC
TCTGTGTTTATTAGCCTTCCAGCCACTGAGAATTTGAACGCTGATTTCAGGTTTTGTGTG
AAGGCAAAGAGGAAAACAAACTTAACTTGGAGTTGCAGAGTAAATAAAACTCAACATGCT
TCTACCAAGTTATTTCTCAACCTGGCAACGCTGCTCCCCTTTTGTGTGTGCCTAATGTCC
TTTTTCCTCTTGATCCTCTCCCTGCGGAGACATATCAGGCGAATGCAGCTCAGTGCCACA
GGGTGCAGAGACCCCAGCACAGAAGCCCATGTGAGAGCCCTGAAAGCTGTCATTTCCTTC
CTTCTCCTCTTTATTGCCTACTATTTGTCCTTTCTCATTGCCACCTCCAGCTACTTTATG
CCAGAGACGGAATTAGCTGTGATTTTTGGTGAGTCCATAGCTCTAATCTACCCCTCAAGT
CATTCATTTATCCTAATACTGGGGAACAATAAATTAAGACATGCATCTCTAAAGGTGATT
TGGAAAGTAATGTCTATTCTAAAAGGAAGAAAATTCCAACAACATAAACAAATCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 318 |
| Molecular Weight
| 36549.5 |
| Theoretical pI
| 10.11 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["10-30", "56-76", "95-115", "129-149", "188-208", "236-256", "267-287"]
|
| Protein Sequence
|
>Taste receptor type 2 member 7
MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWVKKRKIASIDLILTSLAISRICLLC
VILLDCFILVLYPDVYATGKEMRIIDFFWTLTNHLSIWFATCLSIYYFFKIGNFFHPLFL
WMKWRIDRVISWILLGCVVLSVFISLPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHA
STKLFLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISF
LLLFIAYYLSFLIATSSYFMPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVI
WKVMSILKGRKFQQHKQI
|
| External Links |
|---|
| GenBank ID Protein
| 7262613 |
| UniProtKB/Swiss-Prot ID
| Q9NYW3 |
| UniProtKB/Swiss-Prot Entry Name
| TA2R7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF227133 |
| GeneCard ID
| TAS2R7 |
| GenAtlas ID
| TAS2R7 |
| HGNC ID
| HGNC:14913 |
| References |
|---|
| General References
| Not Available |